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010   $a3-7091-1824-7
024 7 $a10.1007/978-3-7091-1824-5
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035   $a(DE-He213)978-3-7091-1824-5
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100   $a20150119d2015      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aTumor Cell Metabolism $ePathways, Regulation and Biology /$fedited by Sybille Mazurek, Maria Shoshan
205   $a1st ed. 2015.
210  1$aVienna :$cSpringer Vienna :$cImprint: Springer,$d2015.
215   $a1 online resource (371 p.)
300   $aDescription based upon print version of record.
311   $a3-7091-1823-9 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aMetabolic Remodeling in Bioenergetic Disorders and Cancer  -- Tumor Cell Complexity and Metabolic Flexibility -- Autophagy and Tumor Cell Metabolism.-Tumour Hypoxia and the Hypoxia-Inducible Transcription -- MYC Regulation of Metabolism and Cancer -- Pyruvate Kinase M2: A Metabolic Tuner -- Role of the Pentose Phosphate Pathway in Tumour Metabolism -- Enzymes of the Tumour Metabolome in Diagnostic Applications -- Contribution of pH Alterations to the Tumor Microenvironment -- Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis? The Relevance of the Mitochondrial H+-ATP Synthase -- Canceromics Studies Unravel Tumor?s Glutamine Addiction -- Essential Role of Mitochondria in Pyrimidine Metabolism -- Metabolic Fluxes in Cancer Metabolism -- Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer.
330   $aThe four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.
606   $aCancer research
606   $aMolecular biology
606   $aOncology  
606   $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001
606   $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
606   $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160
615  0$aCancer research.
615  0$aMolecular biology.
615  0$aOncology  .
615 14$aCancer Research.
615 24$aMolecular Medicine.
615 24$aOncology.
676   $a610
676   $a611.01816
676   $a614.5999
676   $a616994
702   $aMazurek$b Sybille$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aShoshan$b Maria$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910298296403321
996   $aTumor Cell Metabolism$92508864
997   $aUNINA