Imidazole and its derivatives . Part I [[electronic resource] /] / Klaus Hofmann

• Autore: Hofmann Klaus <1911-1995.>
• Pubblicazione: New York, : Interscience, 1953
• Descrizione fisica: 1 online resource (470 p.)
• Disciplina: 547.59; 547/.59/05
• Soggetto topico: Imidazoles; Imidazoles - Derivatives
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: IMIDAZOLE and Its Derivatives; Preface; Contents; Section 1 CHEMISTRY OF CLASSES AND DERIVATIVES; I. General Properties and Structure of the Imidazoles; A. Nomenclature; B. Physical Properties; 1. Introduction; 2. Boiling and Melting Points; 3. Solubility; 4. Molecular Weight and Degree of Association; 5. Viscosity; 6. Dipole Moments; 7. Spectroscopic Properties; (a) Ultraviolet Absorption Spectra; (b) Raman Spectra; (c) Chemiluminescence; 8. Miscellaneous Physical Properties; C. Chemical Properties; 1. Basic Strength; 2. Pseudoacidic Character; 3. Chemical Stability and Aromatic Character ; D. Structural Considerations1. The Classical Imidazole Formula; 2. Current Views; E. Tautomeric Character; II. The Alkyl- and Arylimidazoles; A. Synthetic Procedures; 1. Introduction; 2. The Radziszewski Synthesis; 3. The Weidenhagen Synthesis; 4. Formation from Carbohydrates; 5. Formation from 2(3H)-Imidazolethiones and Dithiohydantoins; 6. Formation from Imidazolecarboxylic Acids; 7. Formation from 2-Imidazolines; 8. Miscellaneous Procedures; B. Properties and Chemical Behavior; 1. General Properties; 2. Acylation; 3. Alkylation ; III. The Oxo- and Hydroxyimidazoles and Their Sulfur AnaloguesA. The Oxoimidazoles; 1. Imidazolecarboxaldehydes; 2. Imidazole Ketones; 3. Imidazolones and Thiones; (a) Nomenclature; (b) Structural Considerations Regarding the 2(3H)-Imidazolones and Thiones; (c) 2(3H)-Imidazolones; (d) 2(3H)-Imidazolethiones; (e) 2(5H)-Imidazolones; (f) 4(5H) (or 5(4H))-Imidazolones; B. The Hydroxyalkylimidazoles; 1. Monohydroxyalkylimidazoles; (a) Hydroxymethylimidazoles; (b) 4(or 5)-(2-Hydroxyethyl)Imidazole; 2. Polyhydroxyalkylimidazoles; (a) 4(or 5)-Polyhydroxyalkylimidazoles ; (b)) l-PolyhydroxyalkylimidazolesIV. The Halogenoimidazoles; A. Bromoimidazoles; 1. Preparative Methods; 2. Properties; B. Chloroimidazoles; C. Chloroalkylimidazoles; D. Iodoimidazoles; 1. Preparative Methods; 2. Properties; V. The Nitro-, Arylazo-, and Aminoimidazoles; A. Nitroimidazoles; 1. Synthetic Methods and Orientation of the Nitro Group; 2. Properties; B. Arylazoimidazoles; 1. Formation and Orientation of the Arylazo Group; 2. Application of the Diazo Test to the Identification and Estimation of Imidazoles; 3. Properties; C. Aminoimidazoles; 1. 2-Aminoimidazoles ; 2. 4(or 5)-AminoimidazolesD. Histamine; 1. Discovery, Distribution in Nature, and Pharmacological Effects; 2. Isolation from Natural Materials; 3. Quantitative Estimation of Histamine; (a) Biological Methods; (b) Colorimetric Methods; 4. Formation by Microorganisms; 5. Preparative Methods; 6. Physical and Chemical Properties; 7. Structural Analogues of Histamine; (a) Position Isomers; (b) Ring-Substitution Products; (c) N-Monoalkyl- and N-Dialkylhistamine Derivatives; (d) Histamine Analogues Possessing Longer or Shorter Aliphatic Side Chains; 8. Pharmacological Specificity ; VI. The Imidazolecarboxylic and Sulfonic Acids
• Sommario/riassunto: Chemistry of Heterocyclic Compounds publishes articles, letters to the Editor, reviews, and minireviews on the synthesis, structure, reactivity, and biological activity of heterocyclic compounds including natural products. The journal covers investigations in heterocyclic chemistry taking place in scientific centers of all over the world, including extensively the scientific institutions in Russia, Ukraine, Latvia, Lithuania and Belarus.
• Titolo autorizzato: Imidazole and its derivatives
• ISBN: 1-282-30139-X; 9786612301391; 0-470-18654-2; 0-470-18804-9
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910144289503321
• Lo trovi qui: Univ. Federico II
• Serie: Chemistry of heterocyclic compounds ; ; v. 6, pt. I.