LEADER 05138nam 2200649Ia 450 001 9910144289503321 005 20170810192851.0 010 $a1-282-30139-X 010 $a9786612301391 010 $a0-470-18654-2 010 $a0-470-18804-9 035 $a(CKB)1000000000376513 035 $a(EBL)469517 035 $a(OCoLC)671802831 035 $a(SSID)ssj0000388224 035 $a(PQKBManifestationID)11278784 035 $a(PQKBTitleCode)TC0000388224 035 $a(PQKBWorkID)10423566 035 $a(PQKB)11729454 035 $a(MiAaPQ)EBC469517 035 $a(PPN)223297038 035 $a(EXLCZ)991000000000376513 100 $a20070725d1953 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aImidazole and its derivatives$hPart I$b[electronic resource] /$fKlaus Hofmann 210 $aNew York $cInterscience$d1953 215 $a1 online resource (470 p.) 225 1 $aChemistry of heterocyclic compounds ;$vv. 6, pt. I 300 $aDescription based upon print version of record. 311 $a0-470-37653-8 320 $aIncludes bibliographical references and index. 327 $aIMIDAZOLE and Its Derivatives; Preface; Contents; Section 1 CHEMISTRY OF CLASSES AND DERIVATIVES; I. General Properties and Structure of the Imidazoles; A. Nomenclature; B. Physical Properties; 1. Introduction; 2. Boiling and Melting Points; 3. Solubility; 4. Molecular Weight and Degree of Association; 5. Viscosity; 6. Dipole Moments; 7. Spectroscopic Properties; (a) Ultraviolet Absorption Spectra; (b) Raman Spectra; (c) Chemiluminescence; 8. Miscellaneous Physical Properties; C. Chemical Properties; 1. Basic Strength; 2. Pseudoacidic Character; 3. Chemical Stability and Aromatic Character 327 $aD. Structural Considerations1. The Classical Imidazole Formula; 2. Current Views; E. Tautomeric Character; II. The Alkyl- and Arylimidazoles; A. Synthetic Procedures; 1. Introduction; 2. The Radziszewski Synthesis; 3. The Weidenhagen Synthesis; 4. Formation from Carbohydrates; 5. Formation from 2(3H)-Imidazolethiones and Dithiohydantoins; 6. Formation from Imidazolecarboxylic Acids; 7. Formation from 2-Imidazolines; 8. Miscellaneous Procedures; B. Properties and Chemical Behavior; 1. General Properties; 2. Acylation; 3. Alkylation 327 $aIII. The Oxo- and Hydroxyimidazoles and Their Sulfur AnaloguesA. The Oxoimidazoles; 1. Imidazolecarboxaldehydes; 2. Imidazole Ketones; 3. Imidazolones and Thiones; (a) Nomenclature; (b) Structural Considerations Regarding the 2(3H)-Imidazolones and Thiones; (c) 2(3H)-Imidazolones; (d) 2(3H)-Imidazolethiones; (e) 2(5H)-Imidazolones; (f) 4(5H) (or 5(4H))-Imidazolones; B. The Hydroxyalkylimidazoles; 1. Monohydroxyalkylimidazoles; (a) Hydroxymethylimidazoles; (b) 4(or 5)-(2-Hydroxyethyl)Imidazole; 2. Polyhydroxyalkylimidazoles; (a) 4(or 5)-Polyhydroxyalkylimidazoles 327 $a(b)) l-PolyhydroxyalkylimidazolesIV. The Halogenoimidazoles; A. Bromoimidazoles; 1. Preparative Methods; 2. Properties; B. Chloroimidazoles; C. Chloroalkylimidazoles; D. Iodoimidazoles; 1. Preparative Methods; 2. Properties; V. The Nitro-, Arylazo-, and Aminoimidazoles; A. Nitroimidazoles; 1. Synthetic Methods and Orientation of the Nitro Group; 2. Properties; B. Arylazoimidazoles; 1. Formation and Orientation of the Arylazo Group; 2. Application of the Diazo Test to the Identification and Estimation of Imidazoles; 3. Properties; C. Aminoimidazoles; 1. 2-Aminoimidazoles 327 $a2. 4(or 5)-AminoimidazolesD. Histamine; 1. Discovery, Distribution in Nature, and Pharmacological Effects; 2. Isolation from Natural Materials; 3. Quantitative Estimation of Histamine; (a) Biological Methods; (b) Colorimetric Methods; 4. Formation by Microorganisms; 5. Preparative Methods; 6. Physical and Chemical Properties; 7. Structural Analogues of Histamine; (a) Position Isomers; (b) Ring-Substitution Products; (c) N-Monoalkyl- and N-Dialkylhistamine Derivatives; (d) Histamine Analogues Possessing Longer or Shorter Aliphatic Side Chains; 8. Pharmacological Specificity 327 $aVI. The Imidazolecarboxylic and Sulfonic Acids 330 $aChemistry of Heterocyclic Compounds publishes articles, letters to the Editor, reviews, and minireviews on the synthesis, structure, reactivity, and biological activity of heterocyclic compounds including natural products. The journal covers investigations in heterocyclic chemistry taking place in scientific centers of all over the world, including extensively the scientific institutions in Russia, Ukraine, Latvia, Lithuania and Belarus. 410 0$aChemistry of heterocyclic compounds ;$vv. 6, pt. I. 606 $aImidazoles 606 $aImidazoles$xDerivatives 615 0$aImidazoles. 615 0$aImidazoles$xDerivatives. 676 $a547.59 676 $a547/.59/05 700 $aHofmann$b Klaus$f1911-1995.$0985036 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910144289503321 996 $aImidazole and its derivatives$92250827 997 $aUNINA