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Good Research Practice in Non-Clinical Pharmacology and Biomedicine / / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler



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Autore: Bespalov Anton Visualizza persona
Titolo: Good Research Practice in Non-Clinical Pharmacology and Biomedicine / / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler Visualizza cluster
Pubblicazione: Springer Nature, 2020
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Edizione: 1st ed. 2020.
Descrizione fisica: 1 online resource (X, 423 p. 34 illus., 21 illus. in color.)
Disciplina: 615
615.1072
Soggetto topico: Pharmacology
Neurosciences
Cardiology
Oncology  
Pharmacology/Toxicology
Oncology
Soggetto non controllato: Pharmacology/Toxicology
Neurosciences
Cardiology
Oncology
Pharmacology
Neuroscience
Internal Medicine
reproducibility
study design
data analysis
data reporting
data integrity
quality management
open access
Cardiovascular medicine
Persona (resp. second.): BespalovAnton
MichelMartin C
StecklerThomas
Nota di contenuto: 1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers’ responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice.
Sommario/riassunto: This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Titolo autorizzato: Good Research Practice in Non-Clinical Pharmacology and Biomedicine  Visualizza cluster
ISBN: 3-030-33656-5
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910380750203321
Lo trovi qui: Univ. Federico II
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Serie: Handbook of Experimental Pharmacology ; ; 257