Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke [[electronic resource] /] / edited by Jun Chen, John H. Zhang, Xiaoming Hu
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| Titolo: |
Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke [[electronic resource] /] / edited by Jun Chen, John H. Zhang, Xiaoming Hu
|
| Pubblicazione: | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Edizione: | 1st ed. 2016. |
| Descrizione fisica: | 1 online resource (XIII, 408 p. 49 illus., 44 illus. in color.) |
| Disciplina: | 616.81 |
| Soggetto topico: | Neurosciences |
| Neurology | |
| Neurology | |
| Persona (resp. second.): | ChenJun |
| ZhangJohn H | |
| HuXiaoming | |
| Nota di bibliografia: | Includes bibliographical references at the end of each chapters. |
| Nota di contenuto: | Part 1. Microvascular integrity in stroke -- 1. Structural alterations to the endothelial tight junction complex during stroke -- 2. Role of pericytes in neurovascular unite and stroke -- 3. Glial support of blood-brain barrier integrity: Molecular targets for novel therapeutic strategies in stroke -- 4. Barrier mechanism in neonatal stroke -- 5. Angiogenesis: a realistic therapy for ischemic stroke -- Part 2. Glial cells in stroke -- 6. Astrocytes as a target for ischemic stroke -- 7. Microglia: a double-sided sword in stroke -- 8. Crosstalk between cerebral endothelium and oligodendrocyte after stroke -- Part 3. Peripheral immune cells in stroke -- 9. The peripheral immune response to stroke -- 10. The Role of spleen-derived immune cells in ischemic brain injury -- 11. Regulatory T cells in ischemic brain injury -- 12. B cells in stroke and preconditioning-induced protection against stroke -- 13. Mast cell as an early responder in ischemic brain injury -- 14. Roles of neutrophils in stroke -- 15. The function of cytokines in ischemic stroke -- Part 4. White matter injury and repair in stroke -- 16. Ischemic injury to white matter: an age-dependent process -- 17. Neurovascular repair after stroke -- 18. The role of non-neuronal Nrf2 pathway in ischemic stroke: damage control and potential tissue repair -- 19. Stem cell therapy for ischemic stroke. |
| Sommario/riassunto: | This book provides a comprehensive overview of the latest research in the role of non-neuronal cells - astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials. |
| Titolo autorizzato: | Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke |
| ISBN: | 3-319-32337-7 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910254528703321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Springer Series in Translational Stroke Research, . 2363-958X