Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry / / edited by Rainer Cramer

• Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
• Edizione: 1st ed. 2016.
• Descrizione fisica: 1 online resource (287 p.)
• Disciplina: 570
• Soggetto topico: Proteins; Mass spectrometry; Industrial microbiology; Biotechnology; Protein Biochemistry; Mass Spectrometry; Industrial Microbiology
• Persona (resp. second.): CramerRainer
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Employing 'second generation' matrices -- (MA)LDI MS mass spectrometry imaging at high specificity and sensitivity -- Techniques for fingermark analysis using MALDI MS - a practical overview -- Whole/Intact Cell MALDI MS Biotyping in Mammalian Cell Analyis -- MALDI biotyping for microorganism identification in clinical microbiology -- Future applications of MALDI-TOF MS in microbiology -- MALDESI: Fundamentals, direct analysis, and MS imaging -- Microprobe MS Imaging of Live Tissues, Cells, and Bacterial Colonies using LAESI -- Efficient production of multiply charged MALDI ions -- Food Authentication by MALDI MS - MALDI-TOF MS Analysis of Fish Species -- Quantitative MALDI MS using Ionic Liquid Matrices -- Disease profiling by MALDI MS analysis of biofluids -- Ionic Liquids and other liquid matrices for sensitive MALDI MS analysis -- Coupling liquid MALDI MS to liquid chromatography.
• Sommario/riassunto: This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization). This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and various application areas, such as cancer proteomics.
• Titolo autorizzato: Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry
• ISBN: 3-319-04819-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910253866803321
• Lo trovi qui: Univ. Federico II