LEADER 04273nam 22006975 450 001 9910253866803321 005 20241023003159.0 010 $a3-319-04819-8 024 7 $a10.1007/978-3-319-04819-2 035 $a(CKB)3710000000501273 035 $a(EBL)4088732 035 $a(SSID)ssj0001583760 035 $a(PQKBManifestationID)16264320 035 $a(PQKBTitleCode)TC0001583760 035 $a(PQKBWorkID)14865300 035 $a(PQKB)11787283 035 $a(DE-He213)978-3-319-04819-2 035 $a(MiAaPQ)EBC4088732 035 $a(PPN)190513896 035 $a(EXLCZ)993710000000501273 100 $a20151109d2016 u| 0 101 0 $aeng 135 $aur|n||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAdvances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry /$fedited by Rainer Cramer 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (287 p.) 300 $aDescription based upon print version of record. 311 1 $a3-319-04818-X 320 $aIncludes bibliographical references and index. 327 $aEmploying 'second generation' matrices -- (MA)LDI MS mass spectrometry imaging at high specificity and sensitivity -- Techniques for fingermark analysis using MALDI MS - a practical overview -- Whole/Intact Cell MALDI MS Biotyping in Mammalian Cell Analysis -- MALDI biotyping for microorganism identification in clinical microbiology -- Future applications of MALDI-TOF MS in microbiology -- MALDESI: Fundamentals, direct analysis, and MS imaging -- Microprobe MS Imaging of Live Tissues, Cells, and Bacterial Colonies using LAESI -- Efficient production of multiply charged MALDI ions -- Food Authentication by MALDI MS - MALDI-TOF MS Analysis of Fish Species -- Quantitative MALDI MS using Ionic Liquid Matrices -- Disease profiling by MALDI MS analysis of biofluids -- Ionic Liquids and other liquid matrices for sensitive MALDI MS analysis -- Coupling liquid MALDI MS to liquid chromatography. 330 $aThis book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on  MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization).  This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: ? Showcases new techniques and applications in MALDI MS ? Demonstrates how MALDI is preferable to ESI ? Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and various application areas, such as cancer proteomics. 606 $aProteins  606 $aMass spectrometry 606 $aProteomics 606 $aMicrobiology 606 $aBiotechnology 606 $aProtein Science$3https://scigraph.springernature.com/ontologies/product-market-codes/L14040 606 $aMass Spectrometry$3https://scigraph.springernature.com/ontologies/product-market-codes/C11010 606 $aProteomics$3https://scigraph.springernature.com/ontologies/product-market-codes/L1403X 606 $aApplied Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12010 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 615 0$aProteins . 615 0$aMass spectrometry. 615 0$aProteomics. 615 0$aMicrobiology. 615 0$aBiotechnology. 615 14$aProtein Science. 615 24$aMass Spectrometry. 615 24$aProteomics. 615 24$aApplied Microbiology. 615 24$aBiotechnology. 676 $a570 702 $aCramer$b Rainer$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910253866803321 996 $aAdvances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry$92529378 997 $aUNINA