Biological inorganic chemistry : a new introduction to molecular structure and function / / Robert R. Crichton

• Autore: Crichton Robert R
• Pubblicazione: Amsterdam ; ; Boston, : Elsevier, 2012
• Edizione: 2nd ed.
• Descrizione fisica: 1 online resource (473 p.)
• Disciplina: 572.51
• Soggetto topico: Bioinorganic chemistry
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front Cover; Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function; Copyright; Contents; Preface to the 2nd Edition; Chapter 1 - An Overview of Metals and Selected Nonmetals in Biology; INTRODUCTION; WHY DO WE NEED ANYTHING OTHER THAN C, H, N, AND O (TOGETHER WITH SOME P AND S)?; WHAT ARE THE ESSENTIAL ELEMENTS AND THE ESSENTIAL METAL IONS?; AN IDIOSYNCRATIC VIEW OF THE PERIODIC TABLE; REFERENCES; Chapter 2 - Basic Coordination Chemistry for Biologists; INTRODUCTION; TYPES OF CHEMICAL BONDS; HARD AND SOFT LIGANDS; COORDINATION GEOMETRY; REDOX CHEMISTRY ; REFERENCESChapter 3 - Structural and Molecular Biology for Chemists; INTRODUCTION; THE STRUCTURAL BUILDING BLOCKS OF PROTEINS; PRIMARY, SECONDARY, TERTIARY, AND QUATERNARY STRUCTURE OF PROTEINS; SECONDARY AND TERTIARY STRUCTURES OF NUCLEIC ACIDS; REFERENCES; Chapter 4 - Biological Ligands for Metal Ions; INTRODUCTION; INSERTION OF METAL IONS INTO METALLOPROTEINS; CHELATASE - THE TERMINAL STEP IN TETRAPYRROLE METALLATION; IRON-SULFUR CLUSTER FORMATION; MORE COMPLEX COFACTORS - MOCO, FEMOCO, P-CLUSTERS, H-CLUSTERS, AND CUZ; SIDEROPHORES; REFERENCES ; Chapter 5 - An Overview of Intermediary Metabolism and BioenergeticsINTRODUCTION; REDOX REACTIONS IN METABOLISM; THE CENTRAL ROLE OF ATP IN METABOLISM; THE TYPES OF REACTION CATALYSED BY ENZYMES OF INTERMEDIARY METABOLISM; AN OVERVIEW OF CATABOLISM; SELECTED CASE STUDIES - GLYCOLYSIS AND THE TRICARBOXYLIC ACID CYCLE; AN OVERVIEW OF ANABOLISM; SELECTED CASE STUDIES: GLUCONEOGENESIS AND FATTY ACID BIOSYNTHESIS; BIOENERGETICS - GENERATION OF PHOSPHORYL TRANSFER POTENTIAL AT THE EXPENSE OF PROTON GRADIENTS; REFERENCES; Chapter 6 - Methods to Study Metals in Biological Systems; INTRODUCTION ; MAGNETIC PROPERTIESELECTRON PARAMAGNETIC RESONANCE (EPR) SPECTROSCOPY; MÖSSBAUER SPECTROSCOPY; NMR SPECTROSCOPY; ELECTRONIC AND VIBRATIONAL SPECTROSCOPIES; CIRCULAR DICHROISM AND MAGNETIC CIRCULAR DICHROISM; RESONANCE RAMAN SPECTROSCOPY; EXTENDED X-RAY ABSORPTION FINE STRUCTURE (EXAFS); X-RAY DIFFRACTION; REFERENCES; Chapter 7 - Metal Assimilation Pathways; INTRODUCTION; INORGANIC BIOGEOCHEMISTRY; METAL ASSIMILATION IN BACTERIA; METAL ASSIMILATION IN FUNGI AND PLANTS; METAL ASSIMILATION IN MAMMALS; REFERENCES; Chapter 8 - Transport, Storage, and Homeostasis of Metal Ions; INTRODUCTION ; METAL STORAGE AND HOMEOSTASIS IN BACTERIAMETAL TRANSPORT, STORAGE, AND HOMEOSTASIS IN PLANTS AND FUNGI; METAL TRANSPORT, STORAGE, AND HOMEOSTASIS IN MAMMALS; REFERENCES; Chapter 9 - Sodium and Potassium - Channels and Pumps; INTRODUCTION - TRANSPORT ACROSS MEMBRANES; SODIUM VERSUS POTASSIUM; POTASSIUM CHANNELS; SODIUM CHANNELS; THE SODIUM-POTASSIUM ATPASE; ACTIVE TRANSPORT DRIVEN BY NA+ GRADIENTS; SODIUM/PROTON EXCHANGERS; OTHER ROLES OF INTRACELLULAR K+; REFERENCES; Chapter 10 - Magnesium-Phosphate Metabolism and Photoreceptors; INTRODUCTION; MAGNESIUM-DEPENDENT ENZYMES ; PHOSPHORYL GROUP TRANSFER KINASES
• Sommario/riassunto: The revised and expanded second edition of Biological Inorganic Chemistry, winner of a 2013 Texty Award from the Text and Academic Authors Association, presents an introduction to this exciting and dynamic field. An increasing understanding of the importance of metals in biology, the environment and medicine, and the multiple roles of metal ions in biological systems, has given rise to biological inorganic chemistry as a field of study. The book begins with an overview of the concepts, both chemical and biological, required for the detailed analysis which follows. Pathways of
• Titolo autorizzato: Biological inorganic chemistry
• ISBN: 1-78268-947-8; 1-283-39629-7; 9786613396297; 0-444-53783-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910825352003321
• Lo trovi qui: Univ. Federico II