LEADER 05294nam 2200649 a 450 001 9910825352003321 005 20200520144314.0 010 $a1-78268-947-8 010 $a1-283-39629-7 010 $a9786613396297 010 $a0-444-53783-X 035 $a(CKB)2670000000140789 035 $a(EBL)858656 035 $a(OCoLC)779141309 035 $a(SSID)ssj0000629763 035 $a(PQKBManifestationID)12239351 035 $a(PQKBTitleCode)TC0000629763 035 $a(PQKBWorkID)10732712 035 $a(PQKB)11575709 035 $a(Au-PeEL)EBL858656 035 $a(CaPaEBR)ebr10539300 035 $a(CaONFJC)MIL339629 035 $a(PPN)182571459 035 $a(FR-PaCSA)88812063 035 $a(MiAaPQ)EBC858656 035 $a(EXLCZ)992670000000140789 100 $a20120405d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiological inorganic chemistry $ea new introduction to molecular structure and function /$fRobert R. Crichton 205 $a2nd ed. 210 $aAmsterdam ;$aBoston $cElsevier$d2012 215 $a1 online resource (473 p.) 300 $aDescription based upon print version of record. 311 $a0-444-53782-1 320 $aIncludes bibliographical references and index. 327 $aFront Cover; Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function; Copyright; Contents; Preface to the 2nd Edition; Chapter 1 - An Overview of Metals and Selected Nonmetals in Biology; INTRODUCTION; WHY DO WE NEED ANYTHING OTHER THAN C, H, N, AND O (TOGETHER WITH SOME P AND S)?; WHAT ARE THE ESSENTIAL ELEMENTS AND THE ESSENTIAL METAL IONS?; AN IDIOSYNCRATIC VIEW OF THE PERIODIC TABLE; REFERENCES; Chapter 2 - Basic Coordination Chemistry for Biologists; INTRODUCTION; TYPES OF CHEMICAL BONDS; HARD AND SOFT LIGANDS; COORDINATION GEOMETRY; REDOX CHEMISTRY 327 $aREFERENCESChapter 3 - Structural and Molecular Biology for Chemists; INTRODUCTION; THE STRUCTURAL BUILDING BLOCKS OF PROTEINS; PRIMARY, SECONDARY, TERTIARY, AND QUATERNARY STRUCTURE OF PROTEINS; SECONDARY AND TERTIARY STRUCTURES OF NUCLEIC ACIDS; REFERENCES; Chapter 4 - Biological Ligands for Metal Ions; INTRODUCTION; INSERTION OF METAL IONS INTO METALLOPROTEINS; CHELATASE - THE TERMINAL STEP IN TETRAPYRROLE METALLATION; IRON-SULFUR CLUSTER FORMATION; MORE COMPLEX COFACTORS - MOCO, FEMOCO, P-CLUSTERS, H-CLUSTERS, AND CUZ; SIDEROPHORES; REFERENCES 327 $aChapter 5 - An Overview of Intermediary Metabolism and BioenergeticsINTRODUCTION; REDOX REACTIONS IN METABOLISM; THE CENTRAL ROLE OF ATP IN METABOLISM; THE TYPES OF REACTION CATALYSED BY ENZYMES OF INTERMEDIARY METABOLISM; AN OVERVIEW OF CATABOLISM; SELECTED CASE STUDIES - GLYCOLYSIS AND THE TRICARBOXYLIC ACID CYCLE; AN OVERVIEW OF ANABOLISM; SELECTED CASE STUDIES: GLUCONEOGENESIS AND FATTY ACID BIOSYNTHESIS; BIOENERGETICS - GENERATION OF PHOSPHORYL TRANSFER POTENTIAL AT THE EXPENSE OF PROTON GRADIENTS; REFERENCES; Chapter 6 - Methods to Study Metals in Biological Systems; INTRODUCTION 327 $aMAGNETIC PROPERTIESELECTRON PARAMAGNETIC RESONANCE (EPR) SPECTROSCOPY; MO?SSBAUER SPECTROSCOPY; NMR SPECTROSCOPY; ELECTRONIC AND VIBRATIONAL SPECTROSCOPIES; CIRCULAR DICHROISM AND MAGNETIC CIRCULAR DICHROISM; RESONANCE RAMAN SPECTROSCOPY; EXTENDED X-RAY ABSORPTION FINE STRUCTURE (EXAFS); X-RAY DIFFRACTION; REFERENCES; Chapter 7 - Metal Assimilation Pathways; INTRODUCTION; INORGANIC BIOGEOCHEMISTRY; METAL ASSIMILATION IN BACTERIA; METAL ASSIMILATION IN FUNGI AND PLANTS; METAL ASSIMILATION IN MAMMALS; REFERENCES; Chapter 8 - Transport, Storage, and Homeostasis of Metal Ions; INTRODUCTION 327 $aMETAL STORAGE AND HOMEOSTASIS IN BACTERIAMETAL TRANSPORT, STORAGE, AND HOMEOSTASIS IN PLANTS AND FUNGI; METAL TRANSPORT, STORAGE, AND HOMEOSTASIS IN MAMMALS; REFERENCES; Chapter 9 - Sodium and Potassium - Channels and Pumps; INTRODUCTION - TRANSPORT ACROSS MEMBRANES; SODIUM VERSUS POTASSIUM; POTASSIUM CHANNELS; SODIUM CHANNELS; THE SODIUM-POTASSIUM ATPASE; ACTIVE TRANSPORT DRIVEN BY NA+ GRADIENTS; SODIUM/PROTON EXCHANGERS; OTHER ROLES OF INTRACELLULAR K+; REFERENCES; Chapter 10 - Magnesium-Phosphate Metabolism and Photoreceptors; INTRODUCTION; MAGNESIUM-DEPENDENT ENZYMES 327 $aPHOSPHORYL GROUP TRANSFER KINASES 330 $aThe revised and expanded second edition of Biological Inorganic Chemistry, winner of a 2013 Texty Award from the Text and Academic Authors Association, presents an introduction to this exciting and dynamic field. An increasing understanding of the importance of metals in biology, the environment and medicine, and the multiple roles of metal ions in biological systems, has given rise to biological inorganic chemistry as a field of study. The book begins with an overview of the concepts, both chemical and biological, required for the detailed analysis which follows. Pathways of 606 $aBioinorganic chemistry 615 0$aBioinorganic chemistry. 676 $a572.51 700 $aCrichton$b Robert R$0520760 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910825352003321 996 $aBiological inorganic chemistry$92094024 997 $aUNINA