| Autore: |
Wagner Nicole
|
| Titolo: |
The Role of PPARs in Disease
|
| Pubblicazione: |
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica: |
1 electronic resource (274 p.) |
| Soggetto topico: |
Medicine |
| |
Physiology |
| Soggetto non controllato: |
peroxisome-proliferator activated receptors |
| |
tumor angiogenesis |
| |
tumor progression |
| |
metastasis formation |
| |
endothelial cells |
| |
RNA sequencing |
| |
PPARs |
| |
toxicology |
| |
pharmacology |
| |
ligand |
| |
vascular |
| |
coronary artery |
| |
lipidomics |
| |
eicosanoids |
| |
inflammation |
| |
CYP450 |
| |
peroxisome proliferator-activated receptor |
| |
angiogenesis |
| |
proliferation |
| |
metastasis |
| |
immortality |
| |
resistance to cell death |
| |
growth suppressors |
| |
immune system |
| |
cellular metabolism |
| |
PPAR |
| |
nuclear receptors |
| |
addiction |
| |
alcohol |
| |
nicotine |
| |
opioids |
| |
psychostimulants |
| |
animal models |
| |
human studies |
| |
Alzheimer’s |
| |
risk factors |
| |
PPARα |
| |
lipids |
| |
fatty acids |
| |
modulators |
| |
cognition |
| |
sex |
| |
therapy |
| |
hypertrophic adipocytes |
| |
PPARG isoforms |
| |
PPARG splicing |
| |
dominant-negative isoform |
| |
in vitro adipocytes |
| |
adipogenesis |
| |
hypertrophic obesity |
| |
insulin-resistance |
| |
peroxisome proliferator-activated receptors (PPARs) |
| |
synthetic agonists |
| |
non-alcoholic fatty liver disease (NAFLD) |
| |
non-alcoholic steatohepatitis (NASH) |
| |
fibrosis |
| |
Sirtuin1 |
| |
peroxisome proliferator-activated receptor-γ coactivator-1α |
| |
peroxisome proliferator activated receptors |
| |
obesity |
| |
metabolic syndrome |
| |
vitamin B12 |
| |
folate |
| |
fetal programming |
| |
inherited metabolic disorders |
| |
PGC-1α, disease |
| |
kidney |
| |
cancer |
| |
AKI |
| |
CKD |
| |
nephron |
| |
PKD |
| |
cilia |
| |
cystogenesis |
| |
ligands |
| |
Alzheimer’s disease (AD) |
| Persona (resp. second.): |
WagnerKay-Dietrich |
| |
WagnerNicole |
| Sommario/riassunto: |
This reprint combines recent original manuscripts and reviews covering the multiple functions of peroxisome proliferator-activated receptors in physiology and pathophysiology. Potential applications and limitations of PPAR agonists and antagonists are discussed. All original contributions were published in Cells. |
| Titolo autorizzato: |
The Role of PPARs in Disease |
|
| Formato: |
Materiale a stampa  |
| Livello bibliografico |
Monografia |
| Lingua di pubblicazione: |
Inglese |
| Record Nr.: | 9910566482503321 |
|
| Lo trovi qui: | Univ. Federico II |
| Opac: |
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