Peroxiredoxin 6 as a Unique Member of the Peroxiredoxin Family
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| Autore: |
Fisher Aron B
|
| Titolo: |
Peroxiredoxin 6 as a Unique Member of the Peroxiredoxin Family
|
| Pubblicazione: | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica: | 1 electronic resource (152 p.) |
| Soggetto non controllato: | NADPH (nicotinamide adenine dinucleotide phosphate) oxidase |
| sperm capacitation | |
| phospholipid hydroperoxide | |
| cornea | |
| peroxidase | |
| phospholipase A2 | |
| 1-Cys Prdx | |
| knock-in mouse | |
| drug delivery | |
| antioxidant activity | |
| sulfinic acid | |
| radioprotection | |
| spermatozoa | |
| peroxiredoxin 6 | |
| mass spectroscopic analysis | |
| knockout mouse | |
| phospholipase A2 activity | |
| liposomes | |
| mitochondrial membrane potential | |
| lipid peroxidation | |
| PLA2 activity | |
| ionizing radiation | |
| glutathione peroxidase | |
| Peroxiredoxin | |
| Prdx6 structure | |
| membrane repair | |
| substrate binding | |
| inflammation | |
| reactive oxygen species | |
| Prdx6 | |
| sulfonic/sulfinic acid | |
| Fuchs' endothelial corneal dystrophy | |
| endothelium | |
| fertilization | |
| peroxidatic cysteine | |
| thioredoxin fold | |
| redox balance | |
| surfactant protein A | |
| diabetes | |
| oxidative stress | |
| Sommario/riassunto: | The peroxiredoxin family was discovered approximately 30 years ago and is now recognized as one of the most important families of enzymes related to antioxidant defense and cellular signaling. Peroxiredoxin 6 shares the basic enzymatic functions that characterize this family, but also exhibits several unique and crucial activities. These include the ability to reduce phospholipid hydroperoxides, phospholipase A2 activity, and an acyl transferase activity that is important in phospholipid remodeling. This book describes the available models for investigating the unique functions of PRDX6 and its role in normal physiological function, as well its roles in the pathophysiology of diseases including cancer, diseases of the eye, and male fertility. |
| Titolo autorizzato: | Peroxiredoxin 6 as a Unique Member of the Peroxiredoxin Family |
| ISBN: | 3-03897-935-X |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910346679603321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |