Delta Opioid Receptor Pharmacology and Therapeutic Applications / / edited by Emily M. Jutkiewicz
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| Titolo: |
Delta Opioid Receptor Pharmacology and Therapeutic Applications / / edited by Emily M. Jutkiewicz
|
| Pubblicazione: | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Edizione: | 1st ed. 2018. |
| Descrizione fisica: | 1 online resource (338 pages) |
| Disciplina: | 615.7822 |
| Soggetto topico: | Pharmacology |
| Neurosciences | |
| Human physiology | |
| Pharmacology/Toxicology | |
| Human Physiology | |
| Persona (resp. second.): | JutkiewiczEmily M |
| Nota di contenuto: | Part 1. DOPR Ligands -- 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept -- 2. Multifunctional Opioid Ligands -- 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins -- Part 2. DOPR Signaling -- 4. Ligand-Directed Signaling at the Delta Opioid Receptor -- 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons -- 6. Evidence and Function Relevance of Native DOR–MOR Heteromers -- Part 3. DOPR and Disease -- 8. The Delta Opioid Receptor in Pain Control -- 9. Delta Opioid Receptors and Modulation of Mood and Emotion -- 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors -- 11. Delta Opioid Receptors: Learning and Motivation -- 12. Delta Opioid Pharmacology in Parkinson’s Disease -- 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders -- 14. Delta Opioid Receptors and Cardioprotection -- 15. The Roles of Opioid Receptors in Cutaneous Wound Healing. . |
| Sommario/riassunto: | This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed. |
| Titolo autorizzato: | Delta opioid receptor pharmacology and therapeutic applications |
| ISBN: | 3-319-95133-5 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910298412803321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Handbook of Experimental Pharmacology, . 0171-2004 ; ; 247