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1. |
Record Nr. |
UNINA990008674830403321 |
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Autore |
Faulks, Keith |
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Titolo |
Citizenship / Keith Faulks |
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Pubbl/distr/stampa |
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London ; New York, : Routledge, c2000 |
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ISBN |
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0-415-19633-7 |
0-415-19634-5 |
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Descrizione fisica |
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Collana |
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Locazione |
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Collocazione |
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2651 sez. Andriello |
LEPORE 748 |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNINA9910298412803321 |
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Titolo |
Delta Opioid Receptor Pharmacology and Therapeutic Applications / / edited by Emily M. Jutkiewicz |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
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ISBN |
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Edizione |
[1st ed. 2018.] |
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Descrizione fisica |
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1 online resource (338 pages) |
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Collana |
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Handbook of Experimental Pharmacology, , 0171-2004 ; ; 247 |
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Disciplina |
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Soggetti |
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Pharmacology |
Neurosciences |
Human physiology |
Pharmacology/Toxicology |
Human Physiology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Part 1. DOPR Ligands -- 1. Delta Opioid Receptor (DOR) Ligands and Pharmacology: Development of Indolo- and Quinolinomorphinan Derivatives Based on the Message-Address Concept -- 2. Multifunctional Opioid Ligands -- 3. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins -- Part 2. DOPR Signaling -- 4. Ligand-Directed Signaling at the Delta Opioid Receptor -- 5. Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons -- 6. Evidence and Function Relevance of Native DOR–MOR Heteromers -- Part 3. DOPR and Disease -- 8. The Delta Opioid Receptor in Pain Control -- 9. Delta Opioid Receptors and Modulation of Mood and Emotion -- 10. Delta Opioid Pharmacology in Relation to Alcohol Behaviors -- 11. Delta Opioid Receptors: Learning and Motivation -- 12. Delta Opioid Pharmacology in Parkinson’s Disease -- 13. Delta Opioid Receptor and Peptide: A Dynamic Therapy for Stroke and Other Neurological Disorders -- 14. Delta Opioid Receptors and Cardioprotection -- 15. The Roles of Opioid Receptors in Cutaneous Wound Healing. . |
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Sommario/riassunto |
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This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed. |
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