Theories of population variation in genes and genomes / / Freddy Bugge Christiansen

• Autore: Christiansen Freddy B. <1946->
• Pubblicazione: Princeton : , : Princeton University Press, , [2008]; ©2008
• Descrizione fisica: 1 online resource (496 p.)
• Disciplina: 576.5/8
• Soggetto topico: Population genetics
• Soggetto genere / forma: Electronic books.
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front matter -- Contents -- Preface and Acknowledgments -- Introduction -- Part I. Genetic Variation -- 1. Genetics -- 2. Conservation of Variation -- 3. Diploid Populations -- 4. Mutation and Variation -- 5. Migration -- 6. Linkage -- 7. Phenotypic Variation -- Part II. Variation and Selection -- 8. Effects of Selection -- 9. Genomic Effects of Selection -- 10. Population Structure -- A. Probability Theory and Statistics -- B. Solutions to Exercises -- Bibliography -- Index
• Sommario/riassunto: This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics
• Titolo autorizzato: Theories of population variation in genes and genomes
• ISBN: 0-691-16589-0; 1-4008-6665-0
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910463615203321
• Lo trovi qui: Univ. Federico II
• Serie: Princeton series in theoretical and computational biology.