LEADER 03921nam 2200661 450 001 9910463615203321 005 20210429202514.0 010 $a0-691-16589-0 010 $a1-4008-6665-0 024 7 $a10.1515/9781400866656 035 $a(CKB)2670000000577646 035 $a(EBL)1864034 035 $a(OCoLC)897069884 035 $a(SSID)ssj0001383766 035 $a(PQKBManifestationID)11764135 035 $a(PQKBTitleCode)TC0001383766 035 $a(PQKBWorkID)11320872 035 $a(PQKB)10891088 035 $a(MiAaPQ)EBC1864034 035 $a(OCoLC)896826724 035 $a(MdBmJHUP)muse49029 035 $a(DE-B1597)459778 035 $a(OCoLC)979905475 035 $a(DE-B1597)9781400866656 035 $a(Au-PeEL)EBL1864034 035 $a(CaPaEBR)ebr10989149 035 $a(CaONFJC)MIL664394 035 $a(EXLCZ)992670000000577646 100 $a20071015h20082008 uy| 0 101 0 $aeng 135 $aur|nu---|u||u 181 $ctxt 182 $cc 183 $acr 200 10$aTheories of population variation in genes and genomes /$fFreddy Bugge Christiansen 210 1$aPrinceton :$cPrinceton University Press,$d[2008] 210 4$dİ2008 215 $a1 online resource (496 p.) 225 1 $aPrinceton series in theoretical and computational biology 300 $aDescription based upon print version of record. 311 0 $a1-322-33112-X 311 0 $a0-691-13367-0 320 $aIncludes bibliographical references and index. 327 $tFront matter --$tContents --$tPreface and Acknowledgments --$tIntroduction --$tPart I. Genetic Variation --$t1. Genetics --$t2. Conservation of Variation --$t3. Diploid Populations --$t4. Mutation and Variation --$t5. Migration --$t6. Linkage --$t7. Phenotypic Variation --$tPart II. Variation and Selection --$t8. Effects of Selection --$t9. Genomic Effects of Selection --$t10. Population Structure --$tA. Probability Theory and Statistics --$tB. Solutions to Exercises --$tBibliography --$tIndex 330 $aThis textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics 410 0$aPrinceton series in theoretical and computational biology. 606 $aPopulation genetics$vTextbooks 608 $aElectronic books. 615 0$aPopulation genetics 676 $a576.5/8 700 $aChristiansen$b Freddy B.$f1946-$01027660 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910463615203321 996 $aTheories of population variation in genes and genomes$92443236 997 $aUNINA