Development of new MDR-tuberculosis drugs / / Jarmila Vinšová and Martin Krátký

• Autore: Vinšová Jarmila
• Pubblicazione: New York, : Nova Science Publishers/Nova Biomedical, c2010
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (112 p.)
• Disciplina: 615.5/8
• Soggetto topico: Antitubercular agents; Multidrug-resistant tuberculosis - Chemotherapy
• Altri autori: KrátkýMartin <1960->
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Resistance to commonly used drugs, mechanism of the action -- Research of novel MDR potential drugs.
• Sommario/riassunto: The emergence of resistance to anti-tuberculosis drugs, particularly of MDR-TB and newly XDR-TB, has become a major public health problem. The current treatment regiment has several disadvantages, i.e. long treatment period (DOTS takes minimum 6 months) during which tubercle bacilli mutant become resistant to one or more drugs; side effects of the used drugs; co-infection of HIV/AIDS. The emergence of MDR-TB has made many currently available anti-TB drugs ineffective. Sleeping latent forms of mutant bacilli resistant against common anti-TB drugs pose the risk of epidemic for the new generation. This book outlines the recent advances in the development of new multi-drug-resistant tuberculosis (MDR-TB) drugs.
• Titolo autorizzato: Development of new MDR-tuberculosis drugs
• ISBN: 1-61668-478-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910967797203321
• Lo trovi qui: Univ. Federico II
• Serie: Pharmacology-research, safety testing, and regulation series.