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Homology, genes, and evolutionary innovation / / Günter P. Wagner



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Autore: Wagner Günter P. Visualizza persona
Titolo: Homology, genes, and evolutionary innovation / / Günter P. Wagner Visualizza cluster
Pubblicazione: Princeton, New Jersey : , : Princeton University Press, , 2014
©2014
Edizione: Course Book
Descrizione fisica: 1 online resource (495 p.)
Disciplina: 571.8/5
Soggetto topico: Developmental genetics
Evolution (Biology)
Genetic regulation
Soggetto non controllato: adaptation
amniotes
angiosperms
autopodium
biological diversity
body parts
body plans
breasts
canalization
cell fate
cell type identity
cell types
cell typogenesis
cells
character identity network
character identity
character origination
character states
characters
cis-regulatory elements
class
common ancestor
common ancestry
cryptic genetic variation
development
developmental biology
developmental evolution
developmental genetics
developmental mechanisms
developmental pathways
developmental types
developmental variation
devo-evo research
digit identity
digit loss
digits
embryonic stem cells
evolution
evolutionary biology
evolutionary developmental biology
evolutionary novelties
feathers
fins
finЬimb transition
flower development
flower organ identity
flower organs
flowers
functional specialization
functionalism
gene duplication
gene expression
gene regulatory networks
genes
genetics
hair
hierarchical homology
homeotic genes
homologous genes
homologs
homology
individuals
innovation
limbs
metaphysics
modularity
molecular genetics
molecular structuralism
morphological characters
morphological variation
natural kinds
natural selection
novel characters
paired fins
pentadactyl limb
perianth
phenotypic diversity
phenotypic evolution
philosophy
population biology
positional information
robustness
scales
science
serial homology
signaling centers
skin appendages
skin derivatives
skin
structuralism
tetrapod hand
tetrapod limbs
transcription factor proteins
transcription factors
transcriptional regulation
transposable elements
typology
variational structuralism
vertebrates
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: Front matter -- Contents -- Preface -- Introduction: What This Book Aims to Do and What It Is Not -- Part I. Concepts and Mechanisms -- Part II. Paradigms and Research Programs -- References -- Index
Sommario/riassunto: Homology-a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird's wing-is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks-that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.
Titolo autorizzato: Homology, genes, and evolutionary innovation  Visualizza cluster
ISBN: 1-4008-5146-7
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910787878003321
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