Good Research Practice in Non-Clinical Pharmacology and Biomedicine / / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler
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| Autore: |
Bespalov Anton
|
| Titolo: |
Good Research Practice in Non-Clinical Pharmacology and Biomedicine / / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler
|
| Pubblicazione: | Springer Nature, 2020 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | |
| Edizione: | 1st ed. 2020. |
| Descrizione fisica: | 1 online resource (X, 423 p. 34 illus., 21 illus. in color.) |
| Disciplina: | 615 |
| 615.1072 | |
| Soggetto topico: | Pharmacology |
| Neurosciences | |
| Cardiology | |
| Oncology | |
| Pharmacology/Toxicology | |
| Oncology | |
| Soggetto non controllato: | Pharmacology/Toxicology |
| Neurosciences | |
| Cardiology | |
| Oncology | |
| Pharmacology | |
| Neuroscience | |
| Internal Medicine | |
| reproducibility | |
| study design | |
| data analysis | |
| data reporting | |
| data integrity | |
| quality management | |
| open access | |
| Cardiovascular medicine | |
| Persona (resp. second.): | BespalovAnton |
| MichelMartin C | |
| StecklerThomas | |
| Nota di contenuto: | 1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers’ responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice. |
| Sommario/riassunto: | This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine. |
| Titolo autorizzato: | Good Research Practice in Non-Clinical Pharmacology and Biomedicine |
| ISBN: | 3-030-33656-5 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910380750203321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Handbook of Experimental Pharmacology ; ; 257