Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials

• Autore: Afonin Kirill
• Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute, 2019
• Descrizione fisica: 1 electronic resource (186 p.)
• Soggetto non controllato: cotranscriptional folding; RNA; conditionally activated; i-motif DNA; spinal cord tumor; fluorescence; dynamic; stability; functional RNA; ribozyme; biological media; RNA aptamers; gene therapy; biosensors; viral vector; ganciclovir; RNA self-assembly; RNA nanoparticle; gene delivery; riboswitch; non-viral gene delivery; NANPs; silver nanoclusters; small-angle neutron scattering; contrast variation; aptamers; RNA logic; fluorogenic RNA; glioblastoma multiforme; RNA interference; nucleic acid nanoparticles; immunostimulation; aggregation; small-angle X-ray scattering; non-viral vector; light-up aptamer; nucleic acid therapeutic; live-cell imaging; DNA nanotechnology; nucleic acid computing; nanopores; structural characterization; siRNA; suicide gene therapy; nucleic acid nanoparticle; cytosine rich sequences; RNA nanotechnology; logic gates; serum; conditional activation
• Sommario/riassunto: Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.
• Titolo autorizzato: Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials
• ISBN: 3-03921-260-5
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910367569503321
• Lo trovi qui: Univ. Federico II