04057nam 22010213a 450 991036756950332120250203235431.09783039212606303921260510.3390/books978-3-03921-260-6(CKB)4100000010106051(oapen)https://directory.doabooks.org/handle/20.500.12854/54903(ScCtBLL)7f02ab9e-237b-48b3-87ad-13eaa3682971(OCoLC)1163822591(oapen)doab54903(EXLCZ)99410000001010605120250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierNucleic Acid Architectures for Therapeutics, Diagnostics, Devices and MaterialsKirill AfoninMDPI - Multidisciplinary Digital Publishing Institute2019Basel, Switzerland :MDPI,2019.1 electronic resource (186 p.)9783039212590 3039212591 Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.Biology, life sciencesbicssccotranscriptional foldingRNAconditionally activatedi-motif DNAspinal cord tumorfluorescencedynamicstabilityfunctional RNAribozymebiological mediaRNA aptamersgene therapybiosensorsviral vectorganciclovirRNA self-assemblyRNA nanoparticlegene deliveryriboswitchnon-viral gene deliveryNANPssilver nanoclusterssmall-angle neutron scatteringcontrast variationaptamersRNA logicfluorogenic RNAglioblastoma multiformeRNA interferencenucleic acid nanoparticlesimmunostimulationaggregationsmall-angle X-ray scatteringnon-viral vectorlight-up aptamernucleic acid therapeuticlive-cell imagingDNA nanotechnologynucleic acid computingnanoporesstructural characterizationsiRNAsuicide gene therapynucleic acid nanoparticlecytosine rich sequencesRNA nanotechnologylogic gatesserumconditional activationBiology, life sciencesAfonin Kirill1305966ScCtBLLScCtBLLBOOK9910367569503321Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials3028074UNINA