03641nam 2200889z- 450 991036756950332120231214133526.03-03921-260-5(CKB)4100000010106051(oapen)https://directory.doabooks.org/handle/20.500.12854/54903(EXLCZ)99410000001010605120202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNucleic Acid Architectures for Therapeutics, Diagnostics, Devices and MaterialsMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (186 p.)3-03921-259-1 Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.cotranscriptional foldingRNAconditionally activatedi-motif DNAspinal cord tumorfluorescencedynamicstabilityfunctional RNAribozymebiological mediaRNA aptamersgene therapybiosensorsviral vectorganciclovirRNA self-assemblyRNA nanoparticlegene deliveryriboswitchnon-viral gene deliveryNANPssilver nanoclusterssmall-angle neutron scatteringcontrast variationaptamersRNA logicfluorogenic RNAglioblastoma multiformeRNA interferencenucleic acid nanoparticlesimmunostimulationaggregationsmall-angle X-ray scatteringnon-viral vectorlight-up aptamernucleic acid therapeuticlive-cell imagingDNA nanotechnologynucleic acid computingnanoporesstructural characterizationsiRNAsuicide gene therapynucleic acid nanoparticlecytosine rich sequencesRNA nanotechnologylogic gatesserumconditional activationAfonin Kirillauth1305966BOOK9910367569503321Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials3028074UNINA