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Glia and inflammation in neurodegenerative disease



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Autore: Yenari M. A Visualizza persona
Titolo: Glia and inflammation in neurodegenerative disease Visualizza cluster
Pubblicazione: [Place of publication not identified], : Nova Science, 2006
Edizione: 1st ed.
Descrizione fisica: 1 online resource (283 pages)
Disciplina: 616.8/0479
Soggetto topico: Nervous system - Degeneration
Inflammation
Nervous System Diseases
Cells
Pathologic Processes
Nervous System
Medicine
Pathological Conditions, Signs and Symptoms
Anatomy
Health Occupations
Disease
Occupations
Neuroglia
Neurodegenerative Diseases
Pathology
Human Anatomy & Physiology
Health & Biological Sciences
Neuroscience
Persona (resp. second.): GiffardRona Greenberg
YenariM. A.
Note generali: Bibliographic Level Mode of Issuance: Monograph
Nota di contenuto: Role of microglia in CNS inflammation / Wolfgang J. Streit ... [et al.] -- Astrocytes as inflammatory cells in acute and chronic neurodegeneration / Valerie Chock and Rona Giffard -- Cell death pathways and the immune response / Jennifer M. Pocock ... [et al.] -- Glial-neuronal cross-talk in neurodegeneration / Michael P. Flavin -- Inflammation in stroke / Xian Nan Tang and Midori A. Yenari -- Inflammatory processes in Alzheimer's disease / Michael T. Heneka -- Neuroinflammation and Parkinson's disease / R. Lee Mosley ... [et al.,] -- Inflammation and ischemia in the developing brain / Zinaida S. Vexler.
Sommario/riassunto: The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brain's resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.
Titolo autorizzato: Glia and inflammation in neurodegenerative disease  Visualizza cluster
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910965892703321
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