LEADER 04077oam 2200901zu 450 001 9910965892703321 005 20251116233336.0 035 $a(CKB)2560000000103601 035 $a(SSID)ssj0000915756 035 $a(PQKBManifestationID)11471051 035 $a(PQKBTitleCode)TC0000915756 035 $a(PQKBWorkID)10869653 035 $a(PQKB)10581468 035 $a(MiAaPQ)EBC3022432 035 $a(BIP)13309118 035 $a(EXLCZ)992560000000103601 100 $a20160829d2006 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aGlia and inflammation in neurodegenerative disease 205 $a1st ed. 210 31$a[Place of publication not identified]$cNova Science$d2006 215 $a1 online resource (283 pages) 225 0 $aNova biomedical Glia and inflammation in neurodegenerative disease 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a1-59454-984-2 327 $aRole of microglia in CNS inflammation / Wolfgang J. Streit ... [et al.] -- Astrocytes as inflammatory cells in acute and chronic neurodegeneration / Valerie Chock and Rona Giffard -- Cell death pathways and the immune response / Jennifer M. Pocock ... [et al.] -- Glial-neuronal cross-talk in neurodegeneration / Michael P. Flavin -- Inflammation in stroke / Xian Nan Tang and Midori A. Yenari -- Inflammatory processes in Alzheimer's disease / Michael T. Heneka -- Neuroinflammation and Parkinson's disease / R. Lee Mosley ... [et al.,] -- Inflammation and ischemia in the developing brain / Zinaida S. Vexler. 330 $aThe brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brain's resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level. 606 $aNervous system$xDegeneration 606 $aInflammation 606 $aNervous System Diseases 606 $aCells 606 $aPathologic Processes 606 $aNervous System 606 $aMedicine 606 $aPathological Conditions, Signs and Symptoms 606 $aAnatomy 606 $aHealth Occupations 606 $aDisease 606 $aOccupations 606 $aNeuroglia 606 $aInflammation 606 $aNeurodegenerative Diseases 606 $aPathology 606 $aHuman Anatomy & Physiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 606 $aNeuroscience$2HILCC 615 0$aNervous system$xDegeneration. 615 0$aInflammation. 615 2$aNervous System Diseases. 615 2$aCells. 615 2$aPathologic Processes. 615 2$aNervous System. 615 2$aMedicine. 615 2$aPathological Conditions, Signs and Symptoms. 615 2$aAnatomy. 615 2$aHealth Occupations. 615 2$aDisease. 615 2$aOccupations. 615 2$aNeuroglia. 615 2$aInflammation. 615 2$aNeurodegenerative Diseases. 615 2$aPathology. 615 7$aHuman Anatomy & Physiology 615 7$aHealth & Biological Sciences 615 7$aNeuroscience 676 $a616.8/0479 700 $aYenari$b M. A$01854338 702 $aGiffard$b Rona Greenberg 702 $aYenari$b M. A. 801 0$bPQKB 906 $aBOOK 912 $a9910965892703321 996 $aGlia and inflammation in neurodegenerative disease$94451480 997 $aUNINA