Microenvironments in haemopoietic and lymphoid differentiation / / [Ruth Porter and Julie Whelan, editors]

• Pubblicazione: London, : Pitman; Summit, N.J., : Distributed in North America by CIBA Pharmaceutical Co., 1981
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (362 p.)
• Disciplina: 596/.01/13
• Soggetto topico: Blood cells; Cell differentiation
• Altri autori: PorterRuth WhelanJulie
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Microenvironments in haemopoietic and lymphoid differentiation; Contents; Introduction: signals, receptors and repertoire in haemopoietic differentiation; Haemopoiesis in mammalian bone marrow; Discussion; Self-renewing haemopoietic progenitor cells and the factors controlling proliferation and differentiation; Discussion; Haemopoietic microenvironments in vitro: ultrastructural aspects; Discussion; Regulation and localization of lymphocyte production in the bone marrow; Discussion; Environmental factors in haemopoietic failure in humans; Discussion ; Mapping cell surface antigen expression on haemopoietic progenitor cells using monoclonal antibodiesDiscussion; Lymphoid differentiation in vitro; Discussion; Microanatomy of the thymus: its relationship to T cell differentiation; Discussion; Expression and function of major histocompatibility complex antigens in the developing thymus: studies on normal and nude mice; Discussion; The human thymic microenvironment; Discussion; Cellular and molecular signals in T cell differentiation; Discussion; General discussion: tolerance and diversification of the T cell repertoire ; Histophysiology of follicular structures and germinal centres in relation to B cell differentiationDiscussion; The role of germinal centres in the generation of immunological memory; Discussion; Antigen-presenting cells, including Langerhans cells, veiled cells and interdigitating cells; Discussion; Differentiation of function among antigen-presenting cells; Discussion; Final general discussion T cell subsets and T cell function; Decision-making in development; Chairman's summing-up; Index of contributors; Subject index
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
• Titolo autorizzato: Microenvironments in haemopoietic and lymphoid differentiation
• ISBN: 9786613694348; 9780470720660; 0470720662; 9781280783951; 1280783958; 9780470718353; 0470718358
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910819036803321
• Lo trovi qui: Univ. Federico II
• Serie: Ciba Foundation symposium ; ; new ser. 84.