04211nam 2200733 a 450 991081903680332120240516065033.09786613694348978047072066004707206629781280783951128078395897804707183530470718358(CKB)1000000000688137(EBL)703905(OCoLC)797918478(SSID)ssj0000715480(PQKBManifestationID)11404029(PQKBTitleCode)TC0000715480(PQKBWorkID)10700968(PQKB)10611063(MiAaPQ)EBC703905(Au-PeEL)EBL703905(CaPaEBR)ebr10575468(CaONFJC)MIL369434(Perlego)2764568(EXLCZ)99100000000068813719810925d1981 uy 0engur|n|---|||||txtccrMicroenvironments in haemopoietic and lymphoid differentiation /[Ruth Porter and Julie Whelan, editors]1st ed.London Pitman ;Summit, N.J. Distributed in North America by CIBA Pharmaceutical Co.19811 online resource (362 p.)Ciba Foundation symposium ;84 (new ser.)Description based upon print version of record.9780470663943 0470663944 9780272796368 0272796360 Includes bibliographical references and indexes.Microenvironments in haemopoietic and lymphoid differentiation; Contents; Introduction: signals, receptors and repertoire in haemopoietic differentiation; Haemopoiesis in mammalian bone marrow; Discussion; Self-renewing haemopoietic progenitor cells and the factors controlling proliferation and differentiation; Discussion; Haemopoietic microenvironments in vitro: ultrastructural aspects; Discussion; Regulation and localization of lymphocyte production in the bone marrow; Discussion; Environmental factors in haemopoietic failure in humans; DiscussionMapping cell surface antigen expression on haemopoietic progenitor cells using monoclonal antibodiesDiscussion; Lymphoid differentiation in vitro; Discussion; Microanatomy of the thymus: its relationship to T cell differentiation; Discussion; Expression and function of major histocompatibility complex antigens in the developing thymus: studies on normal and nude mice; Discussion; The human thymic microenvironment; Discussion; Cellular and molecular signals in T cell differentiation; Discussion; General discussion: tolerance and diversification of the T cell repertoireHistophysiology of follicular structures and germinal centres in relation to B cell differentiationDiscussion; The role of germinal centres in the generation of immunological memory; Discussion; Antigen-presenting cells, including Langerhans cells, veiled cells and interdigitating cells; Discussion; Differentiation of function among antigen-presenting cells; Discussion; Final general discussion T cell subsets and T cell function; Decision-making in development; Chairman's summing-up; Index of contributors; Subject indexThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. Ciba Foundation symposium ;new ser. 84.Blood cellsCongressesCell differentiationCongressesBlood cellsCell differentiation596/.01/13Porter Ruth64811Whelan Julie322651MiAaPQMiAaPQMiAaPQBOOK9910819036803321Microenvironments in haemopoietic and lymphoid differentiation1938556UNINA