Growth factors in biology and medicine / / [editors, David Evered, Jonathan Nugent, and Julie Whelan.]

• Pubblicazione: London, : Pitman Pub., 1985
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (296 p.)
• Disciplina: 612/.6
• Soggetto topico: Growth factors - Physiological effect; Cell proliferation; Cells - Growth - Regulation
• Altri autori: EveredDavid NugentJonathan WhelanJulie
• Note generali: "Symposium on Growth Factors in Biology and Medicine, held at the Ciba Foundation, London, 22-24 January, 1985"--Contents page.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Growth factors in biology and medicine; Contents; Introduction; Growth factors in mammalian embryogen-esis; Discussion; The EGF receptor kinase: evidence for allos- teric activation and intramolecular self-phosphorylation; Discussion; Role of growth factors in oncogenesis: growth factor-proto-oncogene pathways of mitogenesis; Discussion; Signalling mitogene- sis in 3T3 cells: role of Ca*+-sensitive, phospholipid-dependent protein kinase; Discussion; The PDGF-inducible 'compe- tence genes': intracellular mediators of the mitogenic response; Discussion ; Platelet-derived growth factor: its potential roles in wound-healing, atherosclerosis, neoplasia, and growth and developmentDiscussion; Nerve growth factor; Discussion; The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells; Discussion; Haemopoietic growth factors: structure and receptor interac- tions; Discussion; In vivo effects of the insulin-like growth factors (IGFs) in the hypophysectomized rat: comparison with human growth hormone and the possible role of the specific IGF carrier proteins; Discussion ; Protein phosphorylation and growth controlDiscussion; Receptors for the phorbol ester tumour promoters; Discussion; Ectopic peptides released by a human mela- noma cell line that modulate the transformed phenotype; Discussion; A growth regula- tory factor that can both inhibit and stimulate growth; Discussion; Final general discussion Receptor modulation and signalling systems; Biological functions of growth factors; Medical aspects of growth factors; Index of contributors; Subject index
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
• Titolo autorizzato: Growth factors in biology and medicine
• ISBN: 9786613694577; 9781280784187; 1280784180; 9780470720974; 0470720972; 9780470718674; 0470718676
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910806168203321
• Lo trovi qui: Univ. Federico II
• Serie: Ciba Foundation symposium ; ; 116.