LEADER 04310nam 2200769 a 450 001 9910806168203321 005 20240516065141.0 010 $a9786613694577 010 $a9781280784187 010 $a1280784180 010 $a9780470720974 010 $a0470720972 010 $a9780470718674 010 $a0470718676 035 $a(CKB)1000000000688055 035 $a(EBL)703936 035 $a(OCoLC)797918543 035 $a(SSID)ssj0000715056 035 $a(PQKBManifestationID)11394642 035 $a(PQKBTitleCode)TC0000715056 035 $a(PQKBWorkID)10678041 035 $a(PQKB)11131529 035 $a(MiAaPQ)EBC703936 035 $a(Au-PeEL)EBL703936 035 $a(CaPaEBR)ebr10575528 035 $a(CaONFJC)MIL369457 035 $a(Perlego)2768746 035 $a(EXLCZ)991000000000688055 100 $a19880825d1985 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aGrowth factors in biology and medicine /$f[editors, David Evered, Jonathan Nugent, and Julie Whelan.] 205 $a1st ed. 210 $aLondon $cPitman Pub.$d1985 215 $a1 online resource (296 p.) 225 1 $aCiba Foundation symposium ;$v116 300 $a"Symposium on Growth Factors in Biology and Medicine, held at the Ciba Foundation, London, 22-24 January, 1985"--Contents page. 311 08$a9780470664445 311 08$a0470664444 311 08$a9780272798188 311 08$a0272798185 320 $aIncludes bibliographical references and indexes. 327 $aGrowth factors in biology and medicine; Contents; Introduction; Growth factors in mammalian embryogen-esis; Discussion; The EGF receptor kinase: evidence for allos- teric activation and intramolecular self-phosphorylation; Discussion; Role of growth factors in oncogenesis: growth factor-proto-oncogene pathways of mitogenesis; Discussion; Signalling mitogene- sis in 3T3 cells: role of Ca*+-sensitive, phospholipid-dependent protein kinase; Discussion; The PDGF-inducible 'compe- tence genes': intracellular mediators of the mitogenic response; Discussion 327 $aPlatelet-derived growth factor: its potential roles in wound-healing, atherosclerosis, neoplasia, and growth and developmentDiscussion; Nerve growth factor; Discussion; The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells; Discussion; Haemopoietic growth factors: structure and receptor interac- tions; Discussion; In vivo effects of the insulin-like growth factors (IGFs) in the hypophysectomized rat: comparison with human growth hormone and the possible role of the specific IGF carrier proteins; Discussion 327 $aProtein phosphorylation and growth controlDiscussion; Receptors for the phorbol ester tumour promoters; Discussion; Ectopic peptides released by a human mela- noma cell line that modulate the transformed phenotype; Discussion; A growth regula- tory factor that can both inhibit and stimulate growth; Discussion; Final general discussion Receptor modulation and signalling systems; Biological functions of growth factors; Medical aspects of growth factors; Index of contributors; Subject index 330 8 $aThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. 410 0$aCiba Foundation symposium ;$v116. 606 $aGrowth factors$xPhysiological effect$vCongresses 606 $aCell proliferation$vCongresses 606 $aCells$xGrowth$xRegulation$vCongresses 615 0$aGrowth factors$xPhysiological effect 615 0$aCell proliferation 615 0$aCells$xGrowth$xRegulation 676 $a612/.6 701 $aEvered$b David$0857127 701 $aNugent$b Jonathan$0845868 701 $aWhelan$b Julie$0322651 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910806168203321 996 $aGrowth factors in biology and medicine$92117305 997 $aUNINA