Aging in today's environment [[electronic resource] /] / Committee on Chemical Toxicity and Aging, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council

• Pubblicazione: Washington, D.C., : National Academy Press, 1987
• Descrizione fisica: 1 online resource (234 p.)
• Disciplina: 612.67
• Soggetto topico: Older people - Effect of environment on; Aging; Environmental health; Human beings - Effect of environment on
• Altri autori: ButlerRobert N. <1927-2010.> PfitzerEmil A
• Note generali: Committee chairmen: Robert N. Butler and Emil A. Pfitzer.
• Nota di bibliografia: Includes bibliographical references (p. 171-208).
• Nota di contenuto: AGING In Today's Environment; Copyright; Preface; Contents; Executive Summary; AGING AND NUTRITION; AGING AND SUSCEPTIBILITY TO DISEASE; AGING, DISEASE, PHARMACEUTICAL USE, AND CHEMICAL RESPONSE; AGING AND ENVIRONMENTAL FACTORS; MODEL SYSTEMS FOR RESEARCH; CONCLUSIONS; 1 Aging and Environmental Exposure ; BASIS OF THE SCIENTIFIC PROBLEM; STRUCTURE OF THE REPORT; 2 The Aging Population and the Psychosocial Implications of Aging ; DEMOGRAPHIC CONSIDERATIONS OF AN AGING POPULATION; PSYCHOSOCIAL ENVIRONMENT; 3 Principles of Gerontology ; CONCEPTUAL CONTEXT OF GERONTOLOGY; THEORIES OF AGING ; Deterministic TheoriesDevelopmental Switches in Gene Expression; Neuroendocrine-Cascade Theories; Stochastic Theories; Intrinsic Mutagenesis Theory; Protein-Synthesis Error Catastrophe; Free Radicals; Posttranslational Glycation of Proteins and DNA; Thymic Involution as a Pacemaker of Immunosenescence; BIOMARKERS OF AGE OR AGING; ALTERED SUSCEPTIBILITY OF THE AGED; 4 Principles of Toxicology in the Context of Aging ; CHEMICAL FATE AND EFFECT; Absorption; Distribution; Metabolism and Elimination; MECHANISMS OF TOXICITY AT THE MOLECULAR, CELLULAR, AND TISSUE LEVEL; Molecular Action ; Cellular EffectsEffects at the Tissue Level; PHARMACOGENETICS; BIOLOGIC MARKERS; TOXICITY TESTING; 5 Characteristics of the Environment, Aging, and the Aged ; NUTRITION; Effects of Nutrition on Toxicity; Nutrition and Cancer; Nutrition and Aging; Background and Criteria for Evaluating Aging; Food Restriction; Dietary Protein Intake; Dietary Fat Intake; Dietary Carbohydrate Intake; Dietary Vitamin Intake; Dietary Mineral Intake; Special Dietary Requirements of the Aged; PHARMACEUTICALS; Demographic Considerations; Patterns of Drug Use and Drug Prescribing; Ambulatory Populations ; Hospital PopulationsLong-Term-Care Facilities; Medication Compliance in the Elderly; Adverse Drug Reactions; LIFE-STYLE; Deliberate Chemical Exposure; Learned Helplessness; Atrophy of Disuse; Indoor Pollutants; Temperature; Radon; Formaldehyde; Combustion Products; Asbestos; Environmental Tobacco Smoke; Pesticides; 6 Environmental Effects on Age-Associated Diseases and Changes in Organ Function ; DEMOGRAPHICS OF AGE-ASSOCIATED DISEASES; SKIN; VISION; Cataracts; Glaucoma; Diabetic Retinopathy; Aging-Related Macular Degeneration; HEARING; NERVOUS SYSTEM; Changes Associated with Aging ; Induced Disorders and DiseasesNeurotoxicants; RESPIRATORY SYSTEM; CARDIOVASCULAR SYSTEM; RENAL SYSTEM; IMMUNE SYSTEM; SEXUALITY; ROLE OF ENVIRONMENT IN BONE METABOLISM AND VITAMIN D NUTRITION; 7 Model Systems for the Evaluation of Toxic Agents Affecting Aging or Age-Related Diseases ; CONSIDERATIONS IN CHOOSING AND DESIGNING MODEL SYSTEMS; EXAMPLES OF MODEL SYSTEMS; In Vitro Models; Nonmammalian Animal [Models; Mammalian Models; Epidemiologic Models; LIFE-SPAN MODULATION BY DRUG TREATMENT; 8 Conclusions ; 9 Recommendations ; RESEARCH; EDUCATION; FUNDING AND RESOURCES; References ; Appendix Resources for Studying Aging
• Titolo autorizzato: Aging in today's environment
• ISBN: 1-280-18635-6; 9786610186358; 0-309-56748-3
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910780009003321
• Lo trovi qui: Univ. Federico II