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Antitumoral Properties of Natural Products



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Autore: Fabiani Roberto Visualizza persona
Titolo: Antitumoral Properties of Natural Products Visualizza cluster
Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020
Descrizione fisica: 1 electronic resource (344 p.)
Soggetto topico: Research & information: general
Biology, life sciences
Soggetto non controllato: cytotoxic activity
NCI-60 cancer cell line
pristimerin
Salacia crassifolia
Celastraceae
Brazilian Cerrado biome
Salacia elliptica
Cheiloclinium cognatum
Plenckia populnea
Aspergillus fumigatus
Cordyceps sinensis
isochromanes
chiral resolution
ECD calculation
cytotoxicity
coronarin D
JNK
osteosarcoma
Zeylenone
gastric cancer
invasion
migration
apoptosis
anti-cancer agents
anthraquinones
glycosyltransferase
Dendrobium officinale
structure elucidation
anti-tumor activity
plantation mode
AR
Ganoderma tsugae
lipogenesis
prostate cancer
SREBP-1
ursolic acid
betulinic acid
triterpenoids
necrotic
quercetin
quercetagetin
patuletin
lichen
secondary metabolites
tumidulin
stemness potential
colorectal cancer cells
oncogene
transcriptional regulation
neferine
FAK/S6K1
autophagy
human neuroblastoma cells
natural yellow Monascus pigments
water-soluble
antioxidation
MCF-7 cells
phloretin
cell proliferation
inflammation
glucose uptake
Catalpa speciosa
Taxus cuspidata
Magnolia acuminata
phenols
antioxidants
anticancer
Colocasia esculenta
food bioactive
tarin
stable nanocapsules
entrapment efficiency
no-toxicity
preclinical tests
antitumoral activity
chemotherapeutic adjuvant
grape leaves
ASE
TP
Antioxidant activities
Antiproliferative
pro-apoptotic effects
Gene expression
Nutraceuticals
Cucurbitacin B
gefitinib-resistant NSCLC
EGFR
lysosomal degradation
CIP2A
zerumbone
cancer
NF-κB
IL-6/JAK2/STAT3
Akt
FOXO1
multiple myeloma
quality control
naringenin
flavonoids
traditional preparation
cancer stem cells
phytochemicals
plant-derived foods
fruit
vegetable
cell signaling
Artemisia absinthium
endoplasmic reticulum stress
mitochondrial-dependent pathway
melanoma
bee venom
melittin
temozolomide
AKT
MAPK
antrodin C
mTOR
metabolic stability
capsazepine
inflammatory diseases
ROS
TRPV1
PI3K/AKT/mTOR
CLE-10
LC3
MDA-MB-231
lactoferrin hydrolysate
copper
manganese
gastric cancer cells
anti-cancer activity
molecular mechanism
natural product alkaloids
cephalotaxine
protein synthesis inhibition
antiproliferation agents
folk medicine
DLD-1 cells
doxorubicin
chemotherapy
drug resistance
CrataBL
glioblastoma
mesenchymal stem cells
microenvironment
plant lectin
protease inhibitor
cryptolepine
neocryptolepine
isocryptolepine
antiproliferative activity
structure activity relationships
Licochalcone A
ATM-Chk2
13-ethylberberine
mitochondrial ROS
RT-R breast cancer cells
diallyl disulfide
PI3K/Akt/mTOR pathway
Pulsatilla saponin D
SB365
glioblastoma multiforme
autophagic flux inhibition
lysosomal membrane permeabilization
mitochondrial membrane potential
CLEFMA
p38
proanthocyanins
TNF-α
lung adenocarcinoma
natural compounds
cervical cancer
cell cycle arrest
dicentrine
metastasis
glioma
semi-synthetic derivative
ingenol
Euphorbia tirucalli
protein kinase C
seaweed
porphyran
carrageenan
anti-cancer
natural products
Persona (resp. second.): FabianiRoberto
Sommario/riassunto: Cancer is one of the major causes of death worldwide. It is a multifactorial heterogeneous disease characterized by the transformation of normal cells into malignant cells, which acquire an uncontrolled growth, immortality, invasiveness, and ability to form distant metastasis. Natural bioactive molecules may interfere with these processes and inhibit the carcinogenesis process. In this book, new molecules and extracts, mainly derived from plants, have been described as being able to alter tumor cell behavior and target several abnormal molecular pathways in cancer cells. Among different cancer cells, the more studied include those derived from glioblastoma, osteosarcoma, lung, breast and gastric cancer. These natural products could be an attractive source for the development of new preventative and therapeutic agents against cancer. They may be more selective and have weaker adverse effects compared to conventional chemotherapy drugs that are actually used for cancer treatment. Clinical trials are necessary to demonstrate whether the in vitro and in vivo animal data are reproduced in humans before the application of natural products in cancer prevention and treatment.
Titolo autorizzato: Antitumoral Properties of Natural Products  Visualizza cluster
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910557419703321
Lo trovi qui: Univ. Federico II
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