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Autore: | Emanuela Marcenaro |
Titolo: | NK Cell Subsets in Health and Disease: New Developments |
Pubblicazione: | Frontiers Media SA, 2017 |
Descrizione fisica: | 1 electronic resource (243 p.) |
Soggetto non controllato: | ILCs |
inflammation | |
NK cell subsets | |
immunotherapy | |
anti-viral responses | |
anti-tumor responses | |
immune checkpoints | |
Persona (resp. second.): | Luigi D. Notarangelo |
Jordan S. Orange | |
Eric Vivier | |
Sommario/riassunto: | Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology. |
Altri titoli varianti: | NK Cell Subsets in Health and Disease |
Titolo autorizzato: | NK Cell Subsets in Health and Disease: New Developments |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910261136003321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |