Clinical applications of TGF-[beta]
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| Titolo: |
Clinical applications of TGF-[beta]
|
| Pubblicazione: | Chichester ; ; New York, : Wiley, 1991 |
| Descrizione fisica: | 1 online resource (266 p.) |
| Disciplina: | 615/.7 |
| Soggetto topico: | Transforming growth factors-beta - Therapeutic use |
| Altri autori: |
BockGregory
MarshJoan
|
| Note generali: | Based on the Symposium on Clinical Applications of TGF-[beta], held at the Ciba Foundation, London, June 12-14, 1990. |
| Editors: Gregory R. Bock and Joan Marsh. | |
| "A Wiley-Interscience publication." | |
| Nota di bibliografia: | Includes bibliographical references and indexes. |
| Nota di contenuto: | CLINICAL APPLICATIONS OF TGF-B; Contents; Introduction; Multiple forms of TGF-B: distinct promoters and differential expression; TGF-B receptors; Mechanisms in TGF-B action; Regulation of epithelial proliferation by TGF-B; Latent forms of TGF-B: molecular structure and mechanisms of action; General discussion I : The role of TGF-B in the nervous system; TGF-B: a possible autocrine immune regulator; TGF-B and wound healing; General discussion II : A stimulatory effect of transforming growth factors on skin tumour devdopmcnt in vivo; The effects of TGF-B on bone |
| TGF-B1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cellsEffects of TGF-Bs in the liver : cell proliferation and fibrogenesis; Role of TGF-B1 in experimental glomerulonephritis; The role of TGF-B in pulmonary fibrosis; In vivo and in vitro effects of TGF-B1 on normal and neoplastic haemopoiesis; Expression of TGF-B2 in human glioblastoma : a role in resistance to immune rejection?; Index of contributors; Subject index | |
| Sommario/riassunto: | TGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in others. Features the latest information on the TGF-beta family and its receptors. Describes correlations between TGF-beta and certain cancers, including glioblastomas. Also contains reports of preliminary investigations of clinical applications for TGF-beta in many diseases, including leukemia and its use to accelerate wound hea |
| Titolo autorizzato: | Clinical applications of TGF- |
| ISBN: | 1-282-34770-5 |
| 9786612347702 | |
| 0-470-51406-X | |
| 0-470-51407-8 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910876900903321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Ciba Foundation symposium ; ; 157.