Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
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| Autore: |
Liebhoff Anna-Maria
|
| Titolo: |
Detection of pathogenic infections in neurological disorders through recycling of gene expression data / / Anna-Maria Liebhoff
|
| Pubblicazione: | Göttingen : , : Cuvillier Verlag, , [2021] |
| ©2021 | |
| Edizione: | 1. Auflage. |
| Descrizione fisica: | 1 online resource (143 pages) |
| Disciplina: | 579.25 |
| Soggetto topico: | RNA viruses - Research - Methodology |
| Nota di bibliografia: | Includes bibliographical references. |
| Nota di contenuto: | Intro -- 1 Introduction -- 2 Biological background -- 2.1 Ribonucleic acid (RNA) -- 2.2 Small RNA -- 2.3 Sequencing -- 2.4 Microbiology -- 2.5 Neurodegenerative diseases -- 2.6 Pathogens in neurological diseases -- 3 Bioinformatics background -- 3.1 Data sources -- 3.2 Metadata and biological ontologies -- 3.3 Read alignment -- 3.4 Comparative analysis -- 3.5 Metagenomic analysis -- 3.6 Integrated analysis pipelines -- 4 Computer science background -- 4.1 Web development -- 4.2 Data science and machine learning -- 5 Small RNA Expression Atlas (SEA) -- 5.1 Background -- 5.2 System architecture -- 5.3 Implementation -- 5.4 System behavior -- 5.5 Results -- 6 Biological discoveries through SEA -- 6.1 Tissue specificity of small RNA -- 6.2 User data and Parkinson's disease -- 6.3 Pathogens in neurodegenerative diseases -- 6.4 Sex specificity of small RNA in human body -- 6.5 Discussion -- 7 Pathogen detection in RNA-seq data -- 7.1 Background -- 7.2 Identification algorithm -- 7.3 Performance measures -- 7.4 Evaluation -- 8 Path(ogen)s to disease -- 8.1 Analysis pipeline -- 8.2 Burkholderia stabilis in frontotemporal dementia -- 8.3 Discussion -- 9 Conclusion -- Bibliography -- A SEA JSON communication objects -- B Pathonoia algorithms -- C Detailed analysis results. |
| Titolo autorizzato: | Detection of pathogenic infections in neurological disorders through recycling of gene expression data |
| ISBN: | 3-7369-6409-9 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910794549303321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |