Progress in the Chemistry of Organic Natural Products 101 / / edited by A. D. Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi

• Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
• Edizione: 1st ed. 2016.
• Descrizione fisica: 1 online resource (236 p.)
• Disciplina: 540
• Soggetto topico: Chemistry, Organic; Medicinal chemistry; Clinical biochemistry; Organic Chemistry; Medicinal Chemistry; Medical Biochemistry
• Persona (resp. second.): KinghornA. D; FalkHeinz; GibbonsSimon; KobayashiJun'ichi
• Note generali: "2192-4309"--Title page verso.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters.
• Nota di contenuto: Contents; Dimeric Sesquiterpenoids; 1 Introduction; 2 Classification and Distribution; 2.1 Disesquiterpenoid DSs; 2.1.1 Bisabolane Disesquiterpenoids; 2.1.2 Germacrane Disesquiterpenoids; 2.1.3 Guaiane, Pseudoguaiane, and Xanthane Disesquiterpenoids; 2.1.4 Eremophilane Disesquiterpenoids; 2.1.5 Cadinane Disesquiterpenoids; 2.1.6 Eudesmane Disesquiterpenoids; 2.1.7 Lindenane Disesquiterpenoids; 2.1.8 Cuparane, Cyclolaurane, and Herbertane Disesquiterpenoids; 2.1.9 Miscellaneous Disesquiterpenoids; 2.1.10 Compound Disesquiterpenoids; 2.2 Pseudo-disesquiterpenoids ; 2.2.1 Dimeric Aza-sesquiterpenoids2.2.2 Miscellaneous Pseudo-disesquiterpenoids; 3 Structural Elucidation; 3.1 General; 3.2 Mass Spectrometry; 3.3 Nuclear Magnetic Resonance Spectroscopy; 3.4 Single-Crystal X-Ray Diffraction; 3.5 CD and ECD Calculations; 3.6 Chemical Methods; 3.7 Structural Elucidation of Serratustone A; 4 Biological Activity; 4.1 Cytotoxic and Antitumor Activity; 4.2 Anti-inflammatory Activity; 4.3 Immunosuppressive Activity; 4.4 Potassium Channel Blocking and Cardiovascular Activity; 4.5 Antimalarial, Antiprotozoal, Antibacterial, Antifungal, and Antiviral Activity ; 4.6 Neurotrophic Activity4.7 Miscellaneous Activities; 5 Synthesis; 5.1 Biogenesis; 5.1.1 [4+2] Diels-Alder Reactions; 5.1.2 [2+2] Cycloaddition and [6+6] Cycloaddition; 5.1.3 Radical Reactions; 5.1.4 Aldol Reactions; 5.1.5 Esterification, Etherification, and Acetal-Formation Reactions; 5.1.6 Dimerization Through a Linker; 5.1.7 Michael-Type Reactions; 5.2 Chemical Synthesis; 5.2.1 Diels-Alder Cycloaddition; 5.2.2 Oxidative Coupling; 5.2.3 Dimerization with Linkers; 5.2.4 Miscellaneous Dimerization Methods; 6 Conclusions; References; Acetogenins from Annonaceae; 1 Introduction ; 2 Annonaceous Acetogenins in the Plant Kingdom3 Classification of Annonaceous Acetogenins (Since 1997 Until the End of 2014); 3.1 Linear and Epoxy Annonaceous Acetogenins; 3.2 Mono-THF Annonaceous Acetogenins, Including Derivatives with a Mono-THF Ring; 3.3 Bis-THF Annonaceous Acetogenins, Including Derivatives with Adjacent or Non-adjacent Bis-THF Rings; 3.4 Miscellaneous; 4 Chemotaxonomy of the Annonaceae Family; 5 Synthesis of Annonaceous Acetogenins; 5.1 Linear Annonaceous Acetogenins; 5.1.1 Montecristin; 5.1.2 (-)-Muricatacin; 5.1.3 Tonkinelin; 5.2 Mono-THF Annonaceous Acetogenins ; 5.3 Adjacent Bis-THF Annonaceous Acetogenins5.4 Non-adjacent Bis-THF Annonaceous Acetogenins; 5.5 Other AGEs; 5.5.1 Adjacent Type THF-THP AGEs; 5.5.2 Non-adjacent THF-THP Type; 5.5.3 THP Type; 5.5.4 Tri-THF Type; 5.5.5 Bis-lactone Type; 6 Biological Activity and Mechanism of Action of Annonaceous Acetogenins; 6.1 Pesticidal Activities; 6.2 Cytotoxic, Cancer-Related, and Ionophore Activities (Anticancer Activity); 6.3 Neurotoxic Activities; 6.4 Other Activities; 6.4.1 Anti-inflammatory Effects; 6.4.2 Promotion of Biofilm Formation in Microbes; 6.4.3 Interaction of AGEs with Membranes ; 6.4.4 AGEs as Cation Ionophores
• Sommario/riassunto: The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, Laszlo Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The series has featured contributions by seven Nobel laureates: D.H.R. Barton, D. Crowfoot Hodgkin, L. Pauling, K. Alder, O. Diels, P. Karrer, and H. von Euler-Chelpin. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in the field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.
• Titolo autorizzato: Progress in the Chemistry of Organic Natural Products 101
• ISBN: 3-319-22692-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910733716403321
• Lo trovi qui: Univ. Federico II
• Serie: Progress in the Chemistry of Organic Natural Products, . 2192-4309 ; ; 101