Liver diseases in the pediatric intensive care unit : a clinical guide / / Philippe Jouvet, Fernando Alvarez, editors

• Pubblicazione: Cham, Switzerland : , : Springer, , [2021]; ©2021
• Descrizione fisica: 1 online resource (174 pages)
• Disciplina: 616.362
• Soggetto topico: Liver - Diseases; Pediatric gastroenterology; Pediatric intensive care; Malalties del fetge; Gastroenterologia pediàtrica; Medicina intensiva
• Soggetto genere / forma: Llibres electrònics
• Persona (resp. second.): JouvetPhilippe; AlvarezFernando
• Nota di contenuto: Intro -- Preface -- Contents -- Contributors -- Liver Injury and Failure in Critically Ill Children -- Epidemiology -- Pathophysiology of Liver Injury in Critically Ill Patients -- Hypoxic Liver Injury -- Sepsis and Inflammation -- Venous Congestion -- Treatment-Associated Liver Injury -- Parenteral Nutrition-Associated Liver Disease (PNLAD) -- Drug-Induced Liver Injury (DILI) -- Transfusions -- Clinical Presentation and Patterns of Acquired Liver Injury and Failure -- Patterns of Liver Injury -- Clinical Presentation and Evolution -- Diagnosis -- Hypoxic Liver Injury -- Cholestatic Liver Dysfunction -- Pitfalls in Diagnosis -- Aminotransferases -- Bilirubin -- Alkaline Phosphatase -- INR -- Albumin -- Novel Markers and Tests -- Serum Bile Acids Levels -- Indocyanine Green Plasma Disappearance Rate (ICG-PDR) -- Liver Stiffness -- An Approach to Abnormal Liver Tests in the ICU -- Treatment -- Treating the Underlying Cause and Preventing Further Injury -- Treating the Complications -- Specific Treatment and Research -- Conclusion -- References -- Acute Liver Failure -- Definition -- Aetiologies of Acute Liver Failure in Newborn and Infants (Tables 1 and 2) -- Metabolic Diseases -- Indeterminate Hepatitis -- Viral Infections -- Haemophagocytic Lymphohistiocytosis (HLH) -- Foetal Alloimmune Hepatitis -- Giant Cell Hepatitis with Autoimmune Haemolytic Anaemia -- Vascular Disorders/Decrease in Liver Perfusion -- Etiologies of Acute Liver Failure in Children (Tables 1 and 2) -- Indeterminate Hepatitis -- Viral Infections -- Drugs -- Paracetamol/Acetaminophen -- Isoniazid -- Volatile Anaesthetic Agents (Halothane, Desflurane, Enflurane, Isoflurane, and Sevoflurane) -- Anticonvulsant Agents: Phenytoin, Carbamazepine, Valproic acid, and Some of the Newer Anticonvulsants -- Other Drugs -- Toxics -- Autoimmune -- Metabolic -- Hematological Disorders. ; Vascular Disorders -- Clinical Presentation -- Laboratory Tests -- Complications -- Treatments -- Non-specific Treatments -- Specific Treatments -- Extracorporeal Therapy as a Bridge to Liver Transplantation -- Prognosis -- Conclusions -- References -- Acute-on-Chronic Liver Failure -- Definitions and Diagnostic Criteria -- Prevalence -- Etiology -- Etiology of Chronic Liver Disease -- Etiology of the Acute Insult -- Pathogenesis -- Natural History and Outcome of ACLF -- Predictive Models and Mortality -- Management -- Conclusions -- References -- Liver Failure and the Brain -- Pathophysiology -- Hyperammonia -- Glutamine -- Blood Brain Barrier (BBB) -- Glutamate -- Cerebral Autoregulation -- Cerebral Edema -- Epidemiology and Clinical Presentation of HE -- Diagnosis, Monitoring, and Prognosis -- Treatment -- Outcome -- Conclusion -- References -- Liver Failure and the Kidneys -- Introduction -- Physiopathology -- Definition and Diagnosis -- Management -- Conclusion -- References -- Liver Failure and Extracorporeal Therapies -- Renal Replacement Therapies -- RRT Method -- Continuous Renal Replacement Therapies -- Intermittent Hemodialysis -- Peritoneal Dialysis -- Extracorporeal Liver Support Therapies -- Artificial Extracorporeal Liver Support Systems (Table 1) -- Albumin Dialysis -- Therapeutic Plasma Exchange (Plasmapheresis) -- Artificial Extracorporeal Liver Support Efficacy -- Biological Extracorporeal Liver Support Systems -- Conclusion -- References -- Liver Failure and the Lungs -- Introduction -- Lung Inflammation -- PARDS Management -- Intra-abdominal Hypertension -- Diagnosis and Management of IAH -- Hepatopulmonary Syndrome -- Diagnosis and Management of HPS -- Porto-Pulmonary Hypertension -- Diagnosis and Management of POPH -- Treatments and Transplant Consideration -- Hepatic Hydrothorax -- Conclusions -- References. ; Liver Failure and the Heart -- Introduction -- The Heart and the Liver: Anatomic Relationships -- Cardiac Complications of Pediatric Liver Diseases -- High-Output Cardiac Failure -- Pathophysiology -- Clinical Presentation -- Treatment -- Cirrhotic Cardiomyopathy -- Pathophysiology -- Clinical Manifestations -- Treatment -- Hepatic Complications of Pediatric Cardiac Disease -- Hepatic Complications of Acute Cardiac Insufficiency: Ischemic Hepatitis -- Fontan-Associated Liver Disease (FALD) -- Pathophysiology -- Clinical Presentation -- Treatment -- Conclusion -- References -- Liver Failure and Haematopoietic Stem Cell Transplantation -- Introduction -- Sinusoidal Obstructive Syndrome -- Physiopathology -- Risk Factors of SOS -- Clinical Presentation and Diagnosis Criteria -- Prevention -- Treatment -- Fluids Management -- Transfusion Support -- Ventilation -- Nutrition -- Infection Treatments -- Liver Dysfunction Treatment -- Delirium Treatment -- Other Causes of Liver Injury in Children Undergoing HSCT -- Infection -- Hepatotropic Virus -- Sepsis -- Graft Versus Host Disease -- Acute Graft Versus Host Disease -- Chronic Graft Versus Host Disease -- Metabolic -- Parenteral Nutrition-Associated Cholestasis -- Iron Overload -- Drug-Related Injury -- Conclusions -- References -- Liver Transplantation in Critically Ill Children -- Main Aspects of Liver Transplantation in Children -- Surgical Approaches -- Donor Selection -- Outcomes and Surgical Complications -- Waiting for a Transplant -- Indications -- Pretransplant Evaluation and Listing -- Pretransplant Management and Complications on the Waiting List -- Post-transplant Management -- Liver Function -- Monitoring Potential Complications -- Immunosuppression and Rejection -- Conclusion -- References -- Index.
• Titolo autorizzato: Liver Diseases in the Pediatric Intensive Care Unit
• ISBN: 3-030-79132-7
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910495214703321
• Lo trovi qui: Univ. Federico II