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Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease



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Autore: Pasquale Pagliaro Visualizza persona
Titolo: Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease Visualizza cluster
Pubblicazione: Frontiers Media SA, 2019
Descrizione fisica: 1 electronic resource (258 p.)
Soggetto non controllato: Antioxidants
Metabolomics
Stroke
Exercise
ischemia/reperfusion injury
mitochondria and chaperones
Pulmonary hypertention
reactive oxygen and nitrogen species
cardiac preconditioning and postconditioning
Endothelium
Persona (resp. second.): Mariarosaria Santillo
Sommario/riassunto: The role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-contraction coupling and force development has been broadly investigated and in part clarified. On the other hand, many efforts have been focused in clarifying the redox mechanisms involved in cardiovascular diseases like ischemia/reperfusion injury, diabetes-associated cardiovascular dysfunctions, atherosclerosis or hypertension, just to mention the major ones. However, in most cases the two levels of investigation remain separate and not interlaced, failing in the attempt to provide a unified vision of the pathophysiologic mechanisms of cardiovascular diseases. The major aim of the Research Topic has been to collect original papers and review articles dealing with the issue from basic to translation research point of views. The topic includes contributions that highlight different interesting aspects of cardiovascular biology with an integrated approach useful for the development of new ideas and advancements in the field of redox signaling in the control of normal cardiovascular functions and their disruption in diseases.
Altri titoli varianti: Redox and Nitrosative Signaling in Cardiovascular System
Titolo autorizzato: Redox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease  Visualizza cluster
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910346747303321
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