LEADER 02885nam 2200469z- 450 001 9910346747303321 005 20210212 035 $a(CKB)4920000000094241 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/57916 035 $a(oapen)doab57916 035 $a(EXLCZ)994920000000094241 100 $a20202102d2019 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aRedox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease 210 $cFrontiers Media SA$d2019 215 $a1 online resource (258 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-726-5 330 $aThe role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-contraction coupling and force development has been broadly investigated and in part clarified. On the other hand, many efforts have been focused in clarifying the redox mechanisms involved in cardiovascular diseases like ischemia/reperfusion injury, diabetes-associated cardiovascular dysfunctions, atherosclerosis or hypertension, just to mention the major ones. However, in most cases the two levels of investigation remain separate and not interlaced, failing in the attempt to provide a unified vision of the pathophysiologic mechanisms of cardiovascular diseases. The major aim of the Research Topic has been to collect original papers and review articles dealing with the issue from basic to translation research point of views. The topic includes contributions that highlight different interesting aspects of cardiovascular biology with an integrated approach useful for the development of new ideas and advancements in the field of redox signaling in the control of normal cardiovascular functions and their disruption in diseases. 517 $aRedox and Nitrosative Signaling in Cardiovascular System 606 $aPhysiology$2bicssc 610 $aAntioxidants 610 $acardiac preconditioning and postconditioning 610 $aEndothelium 610 $aExercise 610 $aischemia/reperfusion injury 610 $aMetabolomics 610 $amitochondria and chaperones 610 $aPulmonary hypertention 610 $areactive oxygen and nitrogen species 610 $aStroke 615 7$aPhysiology 700 $aPasquale Pagliaro$4auth$01318740 702 $aMariarosaria Santillo$4auth 906 $aBOOK 912 $a9910346747303321 996 $aRedox and Nitrosative Signaling in Cardiovascular System: From Physiological Response to Disease$93033506 997 $aUNINA