Foodomics [[electronic resource] ] : advanced mass spectrometry in modern food science and nutrition / / edited by Alejandro Cifuentes

• Pubblicazione: Hoboken, N.J., : John Wiley & Sons, Inc., 2013
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (582 p.)
• Disciplina: 664/.07
• Soggetto topico: Food - Analysis; Mass spectrometry
• Altri autori: CifuentesAlejandro
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: FOODOMICS; CONTENTS; PREFACE; CONTRIBUTORS; 1 FOODOMICS: PRINCIPLES AND APPLICATIONS; 1.1 INTRODUCTION TO FOODOMICS; 1.1.1 Definition of Foodomics; 1.1.2 Foodomics Tools; 1.2 FOODOMICS APPLICATIONS: CHALLENGES, ADVANTAGES, AND DRAWBACKS; 1.2.1 Food Safety, Quality, and Traceability; 1.2.2 Transgenic Foods; 1.2.3 Foodomics in Nutrition and Health Research; 1.3 FOODOMICS, SYSTEMS BIOLOGY, AND FUTURE TRENDS; ACKNOWLEDGMENTS; REFERENCES; 2 NEXT GENERATION INSTRUMENTS AND METHODS FOR PROTEOMICS; 2.1 INTRODUCTION; 2.1.1 History of Mass Spectrometry-Based Proteomics ; 2.1.2 Overview of Classical Proteomics Techniques2.1.3 Sample Preparation Methods; 2.2 EMERGING METHODS IN PROTEOMICS; 2.2.1 Bottom-up and Top-down Proteomics; 2.2.2 Methods for Quantitative Proteomics; 2.2.3 Post-Translational Protein Modifications Identification Methods; 2.3 THE MOVE FROM SHOTGUN TO TARGETED PROTEOMICS APPROACHES; 2.3.1 Shotgun Proteomics; 2.3.2 Targeted Proteomics; 2.3.3 Tandem Mass Spectrometry versus Selected/Multiple Reaction Monitoring; 2.3.4 Tandem Mass Spectrometry with Alternative Acquisition Methods; 2.3.5 Applications of Targeted Approaches in Food Science ; 2.4 NEW INSTRUMENTAL METHODS FOR PROTEOMICS2.4.1 Fragmentation Methods; 2.4.2 High Mass Accuracy and Fast Scanning Instrumentation; 2.4.3 New Hybrid Instruments; 2.5 BIOINFORMATICS TOOLS; 2.5.1 Algorithms for Protein Identification; 2.5.2 Post-Translational Modifications Identification by Computational Methods; 2.5.3 Processing and Analyzing Proteomics Data; 2.5.4 Proteomics Data Repositories; REFERENCES; 3 PROTEOMIC-BASED TECHNIQUES FOR THE CHARACTERIZATION OF FOOD ALLERGENS; 3.1 INTRODUCTION: WHAT IS FOOD ALLERGY?; 3.2 FOOD ALLERGY: FEATURES AND BOUNDARIES OF THE DISEASE ; 3.3 IMMUNOPATHOLOGY OF FOOD ALLERGY AND ROLE OF PROTEOMICS3.4 IDENTIFICATION OF FOOD ALLERGY EPITOPES; 3.4.1 The Epitopes of Food Allergy; 3.4.2 Proteomic Strategies for Allergen Identification, Detection, and Quantification; 3.4.3 Identification of Linear and Conformational Epitopes; 3.5 EXPRESSION PROTEOMICS AND FUNCTIONAL PROTEOMICS IN FOOD ALLERGY; 3.6 IDENTIFICATION OF ALLERGENS IN TRANSFORMED PRODUCTS; 3.7 CONCLUDING REMARKS; REFERENCES; 4 EXAMINATION OF THE EFFICACY OF ANTIOXIDANT FOOD SUPPLEMENTS USING ADVANCED PROTEOMICS METHODS; 4.1 INTRODUCTION ; 4.1.1 Oxidative Stress in Aging and Disease4.1.2 Dietary Antioxidants; 4.2 METHODS FOR STUDYING THE EFFICACY OF ANTIOXIDANTS; 4.2.1 Carbonylation as a Universal Indicator of Oxidative Stress; 4.2.2 Methods for Purifying Carbonylated Proteins from Complex Mixtures, Mechanistic Studies of Diseases, and the Impact of Antioxidants; 4.3 STRATEGIES USED FOR PROTEOMIC ANALYSIS OF CARBONYLATED PROTEINS AND THE IMPACT OF ANTIOXIDANTS; 4.3.1 Isolating Carbonylated Peptides; 4.3.2 Targeting Carbonylated Proteins as a Group; 4.3.3 Multidimensional Separation; 4.4 STUDYING OXIDATION MECHANISMS ; 4.4.1 Direct Oxidation with ROS
• Sommario/riassunto: Provides the latest ""-omics"" tools to advance the study of food and nutrition The rapidly emerging field of foodomics examines food and nutrition by applying advanced ""-omics"" technologies in order to improve people's health, well-being, and knowledge. Using tools from genomics, transcriptomics, epigenomics, proteomics, and metabolomics, foodomics offers researchers new analytical approaches to solve a myriad of current challenges in food and nutrition science. This book presents the fundamentals of foodomics, exploring the use of advanced mass spectrometry techniques
• Titolo autorizzato: Foodomics
• ISBN: 1-118-53728-9; 1-299-24216-2; 1-118-53731-9; 1-118-53735-1
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910809343703321
• Lo trovi qui: Univ. Federico II
• Serie: Wiley-Interscience series on mass spectrometry.