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Record Nr. |
UNINA9910809343703321 |
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Titolo |
Foodomics : advanced mass spectrometry in modern food science and nutrition / / edited by Alejandro Cifuentes |
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Pubbl/distr/stampa |
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Hoboken, N.J., : John Wiley & Sons, Inc., 2013 |
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ISBN |
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1-118-53728-9 |
1-299-24216-2 |
1-118-53731-9 |
1-118-53735-1 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (582 p.) |
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Collana |
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Wiley series on mass spectrometry |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Food - Analysis |
Mass spectrometry |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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FOODOMICS; CONTENTS; PREFACE; CONTRIBUTORS; 1 FOODOMICS: PRINCIPLES AND APPLICATIONS; 1.1 INTRODUCTION TO FOODOMICS; 1.1.1 Definition of Foodomics; 1.1.2 Foodomics Tools; 1.2 FOODOMICS APPLICATIONS: CHALLENGES, ADVANTAGES, AND DRAWBACKS; 1.2.1 Food Safety, Quality, and Traceability; 1.2.2 Transgenic Foods; 1.2.3 Foodomics in Nutrition and Health Research; 1.3 FOODOMICS, SYSTEMS BIOLOGY, AND FUTURE TRENDS; ACKNOWLEDGMENTS; REFERENCES; 2 NEXT GENERATION INSTRUMENTS AND METHODS FOR PROTEOMICS; 2.1 INTRODUCTION; 2.1.1 History of Mass Spectrometry-Based Proteomics |
2.1.2 Overview of Classical Proteomics Techniques2.1.3 Sample Preparation Methods; 2.2 EMERGING METHODS IN PROTEOMICS; 2.2.1 Bottom-up and Top-down Proteomics; 2.2.2 Methods for Quantitative Proteomics; 2.2.3 Post-Translational Protein Modifications Identification Methods; 2.3 THE MOVE FROM SHOTGUN TO TARGETED PROTEOMICS APPROACHES; 2.3.1 Shotgun Proteomics; 2.3.2 Targeted Proteomics; 2.3.3 Tandem Mass Spectrometry versus Selected/Multiple Reaction Monitoring; 2.3.4 Tandem Mass Spectrometry with Alternative Acquisition Methods; 2.3.5 Applications of Targeted Approaches in |
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Food Science |
2.4 NEW INSTRUMENTAL METHODS FOR PROTEOMICS2.4.1 Fragmentation Methods; 2.4.2 High Mass Accuracy and Fast Scanning Instrumentation; 2.4.3 New Hybrid Instruments; 2.5 BIOINFORMATICS TOOLS; 2.5.1 Algorithms for Protein Identification; 2.5.2 Post-Translational Modifications Identification by Computational Methods; 2.5.3 Processing and Analyzing Proteomics Data; 2.5.4 Proteomics Data Repositories; REFERENCES; 3 PROTEOMIC-BASED TECHNIQUES FOR THE CHARACTERIZATION OF FOOD ALLERGENS; 3.1 INTRODUCTION: WHAT IS FOOD ALLERGY?; 3.2 FOOD ALLERGY: FEATURES AND BOUNDARIES OF THE DISEASE |
3.3 IMMUNOPATHOLOGY OF FOOD ALLERGY AND ROLE OF PROTEOMICS3.4 IDENTIFICATION OF FOOD ALLERGY EPITOPES; 3.4.1 The Epitopes of Food Allergy; 3.4.2 Proteomic Strategies for Allergen Identification, Detection, and Quantification; 3.4.3 Identification of Linear and Conformational Epitopes; 3.5 EXPRESSION PROTEOMICS AND FUNCTIONAL PROTEOMICS IN FOOD ALLERGY; 3.6 IDENTIFICATION OF ALLERGENS IN TRANSFORMED PRODUCTS; 3.7 CONCLUDING REMARKS; REFERENCES; 4 EXAMINATION OF THE EFFICACY OF ANTIOXIDANT FOOD SUPPLEMENTS USING ADVANCED PROTEOMICS METHODS; 4.1 INTRODUCTION |
4.1.1 Oxidative Stress in Aging and Disease4.1.2 Dietary Antioxidants; 4.2 METHODS FOR STUDYING THE EFFICACY OF ANTIOXIDANTS; 4.2.1 Carbonylation as a Universal Indicator of Oxidative Stress; 4.2.2 Methods for Purifying Carbonylated Proteins from Complex Mixtures, Mechanistic Studies of Diseases, and the Impact of Antioxidants; 4.3 STRATEGIES USED FOR PROTEOMIC ANALYSIS OF CARBONYLATED PROTEINS AND THE IMPACT OF ANTIOXIDANTS; 4.3.1 Isolating Carbonylated Peptides; 4.3.2 Targeting Carbonylated Proteins as a Group; 4.3.3 Multidimensional Separation; 4.4 STUDYING OXIDATION MECHANISMS |
4.4.1 Direct Oxidation with ROS |
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Sommario/riassunto |
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Provides the latest ""-omics"" tools to advance the study of food and nutrition The rapidly emerging field of foodomics examines food and nutrition by applying advanced ""-omics"" technologies in order to improve people's health, well-being, and knowledge. Using tools from genomics, transcriptomics, epigenomics, proteomics, and metabolomics, foodomics offers researchers new analytical approaches to solve a myriad of current challenges in food and nutrition science. This book presents the fundamentals of foodomics, exploring the use of advanced mass spectrometry techniques |
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