Chemokines : Chemokines and Their Receptors in Drug Discovery / / edited by Nuska Tschammer

• Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
• Edizione: 1st ed. 2015.
• Descrizione fisica: 1 online resource (248 p.)
• Disciplina: 616.079
• Soggetto topico: Medicinal chemistry; Proteins ; Pharmaceutical technology; Medicinal Chemistry; Receptors; Pharmaceutical Sciences/Technology
• Persona (resp. second.): TschammerNuska
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Introduction -- Insights in the chemokine receptor structures and drug design approaches in chemokine receptors -- Therapeutic targeting of CXCR3 chemokine receptor by small molecules -- Allosteric modulation of chemokine receptors -- Chemokines and their receptors in CNS -- Chemokine receptors in allergy and inflammation.
• Sommario/riassunto: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
• Titolo autorizzato: Chemokines
• ISBN: 3-319-14060-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298621503321
• Lo trovi qui: Univ. Federico II
• Serie: Topics in Medicinal Chemistry, . 1862-2461 ; ; 14