LEADER 03865nam 22006735 450 001 9910298621503321 005 20200630160140.0 010 $a3-319-14060-4 024 7 $a10.1007/978-3-319-14060-5 035 $a(CKB)3710000000371983 035 $a(EBL)1998265 035 $a(OCoLC)904338866 035 $a(SSID)ssj0001465402 035 $a(PQKBManifestationID)11790342 035 $a(PQKBTitleCode)TC0001465402 035 $a(PQKBWorkID)11471683 035 $a(PQKB)10352350 035 $a(DE-He213)978-3-319-14060-5 035 $a(MiAaPQ)EBC1998265 035 $a(PPN)18489588X 035 $a(EXLCZ)993710000000371983 100 $a20150302d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aChemokines $eChemokines and Their Receptors in Drug Discovery /$fedited by Nuska Tschammer 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (248 p.) 225 1 $aTopics in Medicinal Chemistry,$x1862-2461 ;$v14 300 $aDescription based upon print version of record. 311 $a3-319-14059-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction -- Insights in the chemokine receptor structures and drug design approaches in chemokine receptors -- Therapeutic targeting of CXCR3 chemokine receptor by small molecules -- Allosteric modulation of chemokine receptors -- Chemokines and their receptors in CNS -- Chemokine receptors in allergy and inflammation. 330 $aMedicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors. 410 0$aTopics in Medicinal Chemistry,$x1862-2461 ;$v14 606 $aMedicinal chemistry 606 $aProteins  606 $aPharmaceutical technology 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 606 $aReceptors$3https://scigraph.springernature.com/ontologies/product-market-codes/L14110 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 615 0$aMedicinal chemistry. 615 0$aProteins . 615 0$aPharmaceutical technology. 615 14$aMedicinal Chemistry. 615 24$aReceptors. 615 24$aPharmaceutical Sciences/Technology. 676 $a616.079 702 $aTschammer$b Nuska$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298621503321 996 $aChemokines$981982 997 $aUNINA