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Titolo: | Immunological tolerance [[electronic resource] /] / [editors, Gregory R. Bock (organizer) and Jamie A. Goode] |
Pubblicazione: | Chichester ; ; New York, : J. Wiley & Sons, 1998 |
Descrizione fisica: | 1 online resource (250 p.) |
Disciplina: | 571.96 |
616.079 | |
Soggetto topico: | Immunological tolerance |
Autoimmunity | |
Altri autori: | BockGregory GoodeJamie |
Note generali: | "Symposium on Immunological Tolerance, held at the Novartis Foundation, London, 8-10 July 1997"--P. v. |
Nota di bibliografia: | Includes bibliographical references and indexes. |
Nota di contenuto: | IMMUNOLOGICAL TOLERANCE; Contents; Participants; Introduction; Mechanisms of peripheral T cell tolerance; B cell antigen receptor signalling in the balance of tolerance and immunity; General discussion I; The study of self-tolerance using murine haemoglobin as a model self antigen; Tolerance and determinant hierarchy; Molecular genetic studies in lymphocyte apoptosis and human autoimmunity; General discussion II; A role for CTLA-4-mediated inhibitorv J signals in peripheral T cell tolerance? |
Antigen-specific CD4+ T cells that survive after the induction of peripheral tolerance possess an intrinsic lymphokine production defectAntigen-specific tolerance induction and the immunotherapy of experimental autoimmune disease; Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes; Tolerance induction with CD4 monoclonal antibodies; A two-step model for the induction of organ-specific autoimmunity; Cross-presentation of self antigens to CDW T cells: the balance between tolerance and autoimmunity; General discussion III | |
Tolerance induction in mature T lymphocytesT lymphocyte-mediated control of autoimmunity; Final general discussion; Index of contributors; Subject index | |
Sommario/riassunto: | This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self tolerance, partial T cell activation, and the role of apoptosis in tolerance. Careful consideration is also given to the clinical applications of our understanding of immunological tolerance, with specific chapters dealing with T cell activation during tumour therapy, antiantigen specific immune suppression, tolerance in infectious diseases, tolerance during |
Titolo autorizzato: | Immunological tolerance |
ISBN: | 1-282-12249-5 |
9786612122491 | |
0-470-51552-X | |
0-470-51553-8 | |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910829925903321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |