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Titolo: |
Applications of RNA-Seq in Biology and Medicine / / Irina Vlasova-St Louis, editor
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Pubblicazione: | London : , : IntechOpen, , 2021 |
Descrizione fisica: | 1 online resource (142 pages) |
Disciplina: | 572.8633 |
Soggetto topico: | Nucleotide sequence |
Cyclic nucleotides | |
Persona (resp. second.): | Vlasova-St LouisIrina |
Sommario/riassunto: | This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation. |
Titolo autorizzato: | Applications of RNA-Seq in Biology and Medicine ![]() |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910688206103321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |