Protein targeting with small molecules [[electronic resource] ] : chemical biology techniques and applications / / edited by Hiroyuki Osada

• Pubblicazione: Hoboken, N.J., : John Wiley & Sons, c2009
• Descrizione fisica: 1 online resource (310 p.)
• Disciplina: 572.633
• Soggetto topico: Protein binding; Molecular probes
• Altri autori: OsadaH <1954-> (Hiroyuki)
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: PROTEIN TARGETING WITH SMALL MOLECULES; CONTENTS; Contributors; Preface; 1 Chemical Biology Based on Small Molecule-Protein Interaction; 2 Target Profiling of Small Molecules; 3 Novel Applications of Affinity Beads; 4 Recent Developments and Advances in Chemical Arrays; 5 Use of the Phage Display Technique to Identify the Target Protein; 6 Development of Fluorescent Probes for Small Molecules; 7 Development of Small-Molecule Ligands and Inhibitors; 8 Interaction of a Biological Response Modifier with Proteins; 9 Chemical Biology of Cell Motility Inhibitors ; 10 Chemical Biology of Cell Surface Oligosaccharides11 Chemical Genomics Based on Yeast Genetics; 12 Data on Small Molecules and Their Target Proteins; Index
• Sommario/riassunto: Discover the link between the latest chemical biology approaches and novel drug therapies! Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. This indispensable bench companion features up-to-date coverage of advances in chemistry and assesses their impact on developing new therapeutics, making it ideal for chemical biologists and medicinal chemists who a
• Titolo autorizzato: Protein targeting with small molecules
• ISBN: 1-282-27906-8; 9786612279065; 0-470-49501-4; 0-470-49500-6
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910139762403321
• Lo trovi qui: Univ. Federico II