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Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives
| Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy : Future Perspectives |
| Autore | Vermehren Charlotte |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (224 p.) |
| Soggetto topico |
Manufacturing industries
Medicine and Nursing |
| Soggetto non controllato |
2019 Beers criteria
5'nuclease assay 80 and over abacavir acute kidney injury adverse drug reaction adverse drug reactions aged allopurinol antidepressants antiepileptic drugs antipsychotics appropriateness bleeding children chronic clinical pharmacist clozapine CNV copy number variation cost-effectiveness CYP1A2 CYP2D6 CYP2D7P CYP2D8P cytochrome P450 cytochromes deprescribing deprescriptions determinants digital decision-support digital health DOACs drug hypersensitivity drug information service drug interaction checkers drug metabolization drug-drug interactions drug-gene interactions early biomarker electronic medical record electronic prescribing emergency department Ethiopia exosomes extracellular vesicles flucloxacillin general practice genotyping health outcomes health services research high resolution melting HLA hospital pharmacy service HRM loxapine medication adherence medication optimization medication reconciliation medication review medication-based risk score microvesicles multimorbidity nursing homes olanzapine older adults older patients outpatient personalized medicine persons with diabetes pharmacogene expression pharmacogenetics pharmacogenomics phenprocoumon plasma neutrophil gelatinase-associated lipocalin polypharmacy population-based potentially inappropriate medication use prevalence process evaluation quality of life shared medication record SLCO1B1 soluble urokinase plasminogen activator receptor thromboembolism utility youth |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical Utility of Applying PGx and Deprescribing-Based Decision Support in Polypharmacy |
| Record Nr. | UNINA-9910595072903321 |
Vermehren Charlotte
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetic Conditions Affecting the Skeleton : Congenital, Idiopathic Scoliosis and Arthrogryposis
| Genetic Conditions Affecting the Skeleton : Congenital, Idiopathic Scoliosis and Arthrogryposis |
| Autore | Giampietro Philip |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Genetics (non-medical) |
| Soggetto non controllato |
spinal curvatures
scoliosis idiopathic DNA methylation pyrosequencing estrogen receptor 1 ESR1 scoliosis progression adolescent idiopathic scoliosis idiopathic scoliosis exome sequencing spine polygenic variants musculoskeletal disease cytoskeleton extracellular matrix contracture arthrogryposis congenital POC5 cilia genetics spine deformity genetic predisposition complex trait model animal genome wide association study genetic linkage study Amyoplasia DECIPHER (DatabasE of genomiC variation and Phenotype in Humans using Ensemble Resources) CNV (copy number variant) DA (distal arthrogryposis) IPA (ingenuity pathway analysis) HPO (human phenotype ontology) akinesia MYOD IGF2 FGFR1 (Fibroblast growth factor receptor 1) genetic variations congenital scoliosis monozygotic twin epigenome-wide association study bone discordant curve severity differentially methylated region congenital vertebral malformation copy number variant CNV CHRNG distal arthrogryposis type 8 Escobar multiple pterygium syndrome MYH3 protein tyrosine kinase 7 (PTK7) whole exome sequencing |
| ISBN | 3-0365-5976-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Genetic Conditions Affecting the Skeleton |
| Record Nr. | UNINA-9910639995403321 |
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Giampietro Philip
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2020
| Identification and Characterization of Genetic Components in Autism Spectrum Disorders 2020 |
| Autore | Butler Merlin G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (204 p.) |
| Soggetto topico |
Biology, life sciences
Genetics (non-medical) Research & information: general |
| Soggetto non controllato |
15q11.2 BP1-BP2 deletion
22q13.3 duplication ASD assessment ASSR auditory event-related potential auditory steady-state response autism autism spectrum disorder autism spectrum disorders autism spectrum disorders (ASDs) bioinformatics biomarker Broader Autism Phenotype Burnside-Butler syndrome CACNA1C causes CaV1.2 clinical decision support systems (CDSSs) clinical findings CNV cognition dental enamel defect disease biomarkers DNA methylation environmental factors epigenetic factors ERP exome sequencing gene fusion genetic genetic factors genetics genomic characterization heterogeneity human genetics intellectual disabilities interactomics medications metabolomics multiplex family neuropsychiatric behavior development pervasive developmental disorder pharmacogenomics phenotypic subgroups stratified by ASD severity post-synaptic density protein-protein interaction proteomics SHANK3 short QT syndrome simplex families SNP subgroup-associated genes and biological functions syndromes treatment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566463603321 |
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Butler Merlin G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multi-Omics for the Understanding of Brain Diseases
| Multi-Omics for the Understanding of Brain Diseases |
| Autore | Yoon Jong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (204 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
3D culture
abnormal behavior gene set ageing Alzheimer's disease biomarker brain ceramides chloride adducts chromosome 22q11.21 CNV copy number variant CSF de novo mutation DGCR8 differentially expressed genes epigenetics epigenome flow infusion analysis genetic polymorphism glycerophosphocholines human brain hydrogen peroxide lab-on-chip microfluidics miRNAs morphine n/a NAD+ neurological diseases neuroprotective neurotransmitter newborn infant nicotinamide OpenArray organ-on-chip Orthosiphon stamineus plant-derived proteins plasma PPI proteomics region schizophrenia SH-SY5Y cell model SIDS spatiotemporal network sphingolipids synaptic plasticity withdrawal zinc finger domain zinc finger motif zinc finger proteins zinc metalloproteins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349303321 |
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Yoon Jong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peptides for Health Benefits 2019 : Volume 1
| Peptides for Health Benefits 2019 : Volume 1 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (340 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ACE-inhibitory activity
acrylamide airway inflammation alcalase hydrolysate Alzheimer's disease AMD AMP identification and design amyloid amyloid fibrils and endothelial regeneration angiogenic precursor cells angiotensin I converting enzyme anti-biofilm peptides anti-inflammatory antibiotic resistance antifungal activity antigen-specific antihypertensive peptides antimicrobial peptide antimicrobial peptides antimicrobial peptides (AMPs) antimicrobial resistance antioxidant activity antioxidant peptide antiproliferative assay antisepsis, peptide antibiotics apolipoprotein E arthritis asthma Aβ peptide bioactive peptide bioactive peptides biomarkers BIOPEP-UWM database biosynthesis bone erosion cancer antigen cancer stem cells cartilage destruction cathelicidins Cec-analogs Cecropins central nervous system diseases chemoprevention Chlorella sorokiniana chronic diseases Clostridioides difficile CNV collagen collagen peptide colorectal cancer combinatorial library confocal microscopy conjugation copper Crassostrea angulata cryptides CXCR3 cystic fibrosis cytoprotective effect database defensins diseases docetaxel doxorubicin dry-cured pork ham dyslipidemia endothelial dysfunction endothelial progenitor cells energy expenditure enteric nervous system enzyme extra domain B fermentation fetal bovine serum (FBS) fibroblasts fibronectin Fmoc/tBu food intake regulation food-derived foods formyl peptide receptors FPYLRH fresh tissue functional food galanin gender differences glioma GPR10 Histatin-5 host defense peptides Hs02 human antimicrobial peptides human keratinocytes humanized mouse hybrid peptide hydrolysis hydroxyprolyl-glycine (Hyp-Gly) hyperglycemia hypertension immune checkpoint inhibitor immune response immune suppression immunomodulant in silico In situ tetramer staining inflammation inflammatory bowel disease insects intragenic antimicrobial peptide Lactoferricin B (Lfcin B) library design ligands lunasin MDA MDR infectious diseases membrane activity MHC tetramer migration miiuy croaker (Miichthys miiuy) mode of action molecular blind docking molecular docking molecular weight monocyte MRSA multimeric peptides mutagenesis n/a nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) neuroprotection neurotensin NF-κB non-atopic asthma nutraceuticals nutrition obesity oral delivery osteostatin oxidative stress pegylated glucagon-like peptide 1 peptide peptide vaccine peptide-drug conjugate physico-chemical properties PI3K/Akt pathway pidotimod pig piscidins platelets polymicrobial biofilms pro-inflammatory pro-inflammatory cytokines prolactin-releasing peptide prolyl-hydroxyproline (Pro-Hyp) prostate cancer protection ability proteolysis proteome microarray proteomics pseudin-2 Pseudomonas aeruginosa pulmonary emphysema RF-amide peptides rheumatic diseases screening sheepskin signaling Sjögren's syndrome SMILES code solid-phase synthesis sPLA2 Staphylococcus aureus stomach swim bladder synergistic effects synergy T cell T cells targeting temporin therapeutic potential type 1 diabetes vasoactive intestinal peptide VEGFR1 velvet antler VPAC1 receptor VPAC2 receptor whey peptides Αβ oligomer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557631703321 |
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Hernández-Ledesma Blanca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peptides for Health Benefits 2019 : Volume 2
| Peptides for Health Benefits 2019 : Volume 2 |
| Autore | Hernández-Ledesma Blanca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (342 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ACE-inhibitory activity
acrylamide airway inflammation alcalase hydrolysate Alzheimer's disease AMD AMP identification and design amyloid amyloid fibrils and endothelial regeneration angiogenic precursor cells angiotensin I converting enzyme anti-biofilm peptides anti-inflammatory antibiotic resistance antifungal activity antigen-specific antihypertensive peptides antimicrobial peptide antimicrobial peptides antimicrobial peptides (AMPs) antimicrobial resistance antioxidant activity antioxidant peptide antiproliferative assay antisepsis, peptide antibiotics apolipoprotein E arthritis asthma Aβ peptide bioactive peptide bioactive peptides biomarkers BIOPEP-UWM database biosynthesis bone erosion cancer antigen cancer stem cells cartilage destruction cathelicidins Cec-analogs Cecropins central nervous system diseases chemoprevention Chlorella sorokiniana chronic diseases Clostridioides difficile CNV collagen collagen peptide colorectal cancer combinatorial library confocal microscopy conjugation copper Crassostrea angulata cryptides CXCR3 cystic fibrosis cytoprotective effect database defensins diseases docetaxel doxorubicin dry-cured pork ham dyslipidemia endothelial dysfunction endothelial progenitor cells energy expenditure enteric nervous system enzyme extra domain B fermentation fetal bovine serum (FBS) fibroblasts fibronectin Fmoc/tBu food intake regulation food-derived foods formyl peptide receptors FPYLRH fresh tissue functional food galanin gender differences glioma GPR10 Histatin-5 host defense peptides Hs02 human antimicrobial peptides human keratinocytes humanized mouse hybrid peptide hydrolysis hydroxyprolyl-glycine (Hyp-Gly) hyperglycemia hypertension immune checkpoint inhibitor immune response immune suppression immunomodulant in silico In situ tetramer staining inflammation inflammatory bowel disease insects intragenic antimicrobial peptide Lactoferricin B (Lfcin B) library design ligands lunasin MDA MDR infectious diseases membrane activity MHC tetramer migration miiuy croaker (Miichthys miiuy) mode of action molecular blind docking molecular docking molecular weight monocyte MRSA multimeric peptides mutagenesis n/a nano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS) neuroprotection neurotensin NF-κB non-atopic asthma nutraceuticals nutrition obesity oral delivery osteostatin oxidative stress pegylated glucagon-like peptide 1 peptide peptide vaccine peptide-drug conjugate physico-chemical properties PI3K/Akt pathway pidotimod pig piscidins platelets polymicrobial biofilms pro-inflammatory pro-inflammatory cytokines prolactin-releasing peptide prolyl-hydroxyproline (Pro-Hyp) prostate cancer protection ability proteolysis proteome microarray proteomics pseudin-2 Pseudomonas aeruginosa pulmonary emphysema RF-amide peptides rheumatic diseases screening sheepskin signaling Sjögren's syndrome SMILES code solid-phase synthesis sPLA2 Staphylococcus aureus stomach swim bladder synergistic effects synergy T cell T cells targeting temporin therapeutic potential type 1 diabetes vasoactive intestinal peptide VEGFR1 velvet antler VPAC1 receptor VPAC2 receptor whey peptides Αβ oligomer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Peptides for Health Benefits 2019 |
| Record Nr. | UNINA-9910557492903321 |
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Hernández-Ledesma Blanca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Cancer Systems Biology
| Recent Developments in Cancer Systems Biology |
| Autore | Sinha Raghu |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (272 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myeloid leukemia
bioinformatics biomarker Boolean model brain-tumor-initiating cell (BTIC) breast cancer cancer genomics cancer progression cancer stem cells cancer systems biology circulating miR-1246 clinical trials CNV computational methods diagnostic biomarker differential expression docking drug repurposing drug resistance Elk-1 Ets ETS Ets-1 experimental model systems genomics glioma glycomics glycosaminoglycan binding knockdown lung adenocarcinoma lung adenocarcinoma (LUAD) lung cancer lung squamous cell carcinoma (LUSC) metabolomics metagenomics microarray n/a network next-generation sequencing non-small-cell lung cancer omics optical genome mapping ovarian pancreatic cancer patient survival patient-derived organoids patient-derived xenografts PEA3 personalized medicine PI3K-Akt signaling pathways prognosis prognostic biomarker protein interactome proteomics renal cancers risk group Sestrin2 signature single-cell sequencing SNV solid tumors stem cell survival systems biology TargetScan TCGA transcriptomics triple-negative breast cancer UBE2C virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557768503321 |
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Sinha Raghu
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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