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Bipolar disorder : from neuroscience to treatment / / Allan H. Young, Mario F. Juruena, editors
| Bipolar disorder : from neuroscience to treatment / / Allan H. Young, Mario F. Juruena, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (viii, 325 pages) |
| Disciplina | 616.89506 |
| Collana | Current Topics in Behavioral Neurosciences |
| Soggetto topico |
Bipolar disorder - Treatment
Trastorn bipolar Terapèutica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-72143-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- The Neurobiology of Bipolar Disorder -- 1 Introduction -- 2 Neurotransmitters -- 2.1 Serotoninergic System -- 2.2 Dopaminergic System -- 2.3 Norepinephrinergic System -- 2.4 GABAergic System -- 2.5 Glutamatergic System -- 3 Intracellular Signalling -- 4 Adenylate Cyclase Signalling Pathway -- 5 Neurotrophins and Neurogenesis -- 6 Neuroendocrine -- 7 Conclusion -- References -- The Role of Stress in Bipolar Disorder -- 1 Introduction -- 1.1 Activation of Hormonal Systems After Stress -- 1.2 Stress Hormone Receptors -- 2 Stress Hormone Actions on the Brain in Healthy Individuals -- 2.1 Cellular Effects of Stress Hormones on Brain Circuits -- 2.2 Neuronal Circuits and Cognitive Function -- 3 Changes in Stress Responsiveness in Bipolar Disorder -- 3.1 Imbalance in the Stress System: Importance of Genetic and (Early) Life History -- 3.2 Changes in the HPA Axis in Bipolar Disorder Patients -- 4 Changes in Cognitive Function in Bipolar Disorder Related to Stress -- 4.1 Time-Dependent Changes in Cognitive Processing Following Stress in BD Patients -- 4.2 Network Function in BP Patients and Individuals at Risk for Psychopathology -- 5 Concluding Remarks -- References -- The Role of Genetics in Bipolar Disorder -- 1 Introduction: Why Genetics Matters in the Susceptibility to Bipolar Disorder? -- 2 Bipolar Disorder Is Heritable: Twin, Adoption, and Family Studies -- 3 How Many Genes Modulate the Risk of Bipolar Disorder? Linkage Studies, Candidate Gene Studies, and Genome-Wide Association S... -- 4 Genetic Overlap Between Bipolar Disorder and Other Brain Disorders: Disorder-Specific or General Genetic Influences? -- 5 The Role of Rare Genetic Variants -- 6 Gene x Environment Studies -- 7 Nongenetic Mechanisms Contributing to the Regulation of Gene Expression: Epigenetics -- 8 Current and Future Lines of Research.
9 Conclusion -- References -- Targeting Mitochondrial Dysfunction for Bipolar Disorder -- 1 The Mitochondria -- 1.1 Mitochondria as an Energy Source -- 1.2 Other Functions of Mitochondria -- 2 Reactive Oxygen Species and Oxidative Stress -- 3 Mitochondria in Bipolar Disorder -- 3.1 Possible Mechanisms of Mitochondrial Dysfunction in Bipolar Disorder -- 3.1.1 A Shift from OXPHOS to Glycolysis -- 3.1.2 Creatine Kinase -- 3.1.3 Calcium -- 3.1.4 Increased Oxidative Stress -- 3.1.5 Neurotransmitters -- 3.1.6 Brain-Derived Neurotrophic Factor (BDNF) -- 3.1.7 NAA -- 3.1.8 Bcl-2 -- 3.2 Mitochondrial Genes -- 4 How Conventional Drugs for Bipolar Disorder Relate to Mitochondrial Functioning -- 5 Mitochondrial Potential Treatments -- 5.1 Likely Beneficial -- 5.1.1 PPAR Agonists -- 5.1.2 Minocycline -- 5.1.3 N-Acetyl-Cysteine (NAC) -- 5.1.4 Co-enzyme Q10 -- 5.1.5 Melatonin -- 5.2 Theoretically Beneficial, but No Studies Have Been Published -- 5.2.1 Ebselen -- 5.2.2 Mangosteen -- 5.2.3 Ketogenic Diet -- 5.2.4 Resveratrol -- 5.2.5 Taurine -- 5.3 Unlikely to Be Beneficial -- 5.3.1 Alpha-Lipoic Acid (ALA) -- 5.3.2 Pyrimidines -- 5.4 Potential Risk of a Manic Switch -- 5.4.1 ALC (Acetyl-L-Carnitine) -- 5.4.2 Creatine Monohydrate (CM) -- 5.4.3 SAMe (S-Adenosyl-Methionine) -- 5.5 Vitamins -- 5.5.1 Vitamin A -- 5.5.2 Vitamin C -- 5.5.3 Vitamin D -- 5.5.4 Vitamin E -- 5.5.5 Vitamins B -- 6 Summary -- References -- Intracellular Signaling Cascades in Bipolar Disorder -- 1 Introduction -- 2 Mitochondrial Dysfunction -- 3 Calcium Channel Modulators -- 4 Intracellular Signaling and Inflammation -- 5 Glycogen Synthase Kinase 3-Beta (GSK3β) -- 6 Protein Kinase C (PKC) and Diacylglycerol (DAG) -- 7 Neurotrophins -- 8 Glutamatergic System -- 9 Dopaminergic System -- 10 Neurohormonal System -- 11 Purinergic System and Mania -- 12 Conclusion -- References. Sleep and Circadian Rhythm Disorder in Bipolar Affective Disorder -- 1 Bipolar Affective Disorder -- 2 Circadian Rhythm -- 3 Circadian Rhythm and Bipolar Affective Disorder -- 4 Circadian Rhythm Sleep-Wake Disorders -- 4.1 Delayed Sleep Phase Disorder -- 5 Genetics -- 6 Chronotype -- 7 Melatonin and Cortisol -- 8 Social Zeitgeber Theory -- 9 Circadian Rhythm and Bipolar Disorder -- 10 Conclusion -- References -- Neuroendocrine Stress System in Bipolar Disorder -- 1 Introduction -- 2 Endocrine Axis -- 2.1 Regulation of the Hypothalamic-Pituitary-Adrenal Axis -- 2.2 The Glucocorticoid Receptor (GR) -- 2.3 Mineralocorticoid Receptors (MRs) -- 2.4 Molecular Mechanisms for Resistance of Glucocorticoid Receptors -- 3 Abnormalities of the HPA Axis in Depression -- 3.1 Impact of Stress on Bipolar Disorders -- 3.2 Impact of Mediating Factors on the HPA Axis -- 4 Factors Associated with an Endophenotype Increasing Vulnerability -- 5 Conclusion -- References -- Neuroanatomic and Functional Neuroimaging Findings -- 1 Introduction -- 2 Structural Neuroimaging and Diffusion Tensor Imaging Studies -- 2.1 Structural Magnetic Resonance Imaging MRI (sMRI) Findings in BD -- 2.2 Diffusion Tensor Imaging (DTI) Findings in BD -- 2.3 Longitudinal sMRI and DTI Findings -- 3 Functional Neuroimaging -- 3.1 Positron Emission Tomography (PET) -- 3.2 Resting-State Functional MRI (rsfMRI) -- 4 Summary of Main Findings -- 5 Diagnostic Specificity of Neuroimaging Findings -- 5.1 Structural Neuroimaging and DTI Findings -- 5.2 Functional Neuroimaging Findings (PET, rs-fMRI) -- 5.3 Neuroimaging and Pattern Classification Methods and the Diagnosis of BD -- 6 Perspectives on the Role of Neuroimaging in the Management of BD Patients -- 6.1 Neuroimaging Studies and Bipolar Disorders Mood States -- 6.2 Neuroimaging Studies, Bipolar Disorders, and Pharmacological Treatment. 6.3 Neuroimaging to Predict Pharmacological Treatment Response -- 6.4 Neuroimaging and Psychotherapy in Bipolar Disorders -- 7 Conclusions -- References -- Structural and Functional Brain Correlates of Neuroprogression in Bipolar Disorder -- 1 Introduction -- 2 Structural Aspects of Neuroprogression in Neuroimaging -- 2.1 Evidence from Cross-Sectional Studies -- 2.1.1 Brain Volume and General Findings -- 2.1.2 Prefrontal Cerebral Cortex -- 2.1.3 Cingulate Cortex -- 2.1.4 Temporal-Limbic Structures -- 2.1.5 Other Brain Structures -- 2.2 Evidence from Longitudinal Studies -- 2.2.1 Brain Volume and General Findings -- 2.2.2 Prefrontal Cerebral Cortex -- 2.2.3 Cingulate Cortex -- 2.2.4 Temporal-Limbic Structures -- 3 Functional Aspects of Neuroprogression in Neuroimaging -- 4 Challenges (Limitations) and Perspectives -- References -- Inflammation as a Mechanism of Bipolar Disorder Neuroprogression -- 1 Introduction -- 2 Evidence of Inflammatory and Infectious Diseases in BD Neuroprogression -- 2.1 Maternal Immune Activation as a Risk Factor for BD Development and Neuroprogression -- 2.2 Role of Infectious Disease as a Trigger to Develop BD Neuroprogression -- 2.3 Autoimmune Disorders and Their Association with BD Neuroprogression -- 2.4 Role of the Gut-Brain Axis on BD Neuroprogression -- 3 Inflammatory and Oxidative Mechanisms in BD Neuroprogression -- 3.1 Mechanisms of Inflammation and Their Contribution to BD Neuroprogression -- 3.2 Oxidative Stress and Mitochondrial Dysfunction Associated with BD Neuroprogression -- 3.3 Peripheral Inflammatory Mediators as a Trigger or Accelerator of BD Neuroprogression -- 3.4 Cerebrospinal Fluid (CSF) System Inflammatory Markers in BD Neuroprogression -- 3.5 Postmortem Inflammatory Markers in BD Neuroprogression -- 4 Conclusions and Future Directions -- References -- Neuropsychology of Bipolar Disorder. 1 Pattern and Magnitude of Impairment -- 2 What Are the Factors that Affect Cognition? -- 2.1 Diagnostic Features -- 2.2 Sleep -- 2.3 Physical Health -- 2.4 Medication -- 3 Summary -- 4 Methods of Assessment -- 4.1 Longitudinal Changes -- 4.2 Identifying Neuropsychological Phenotypic Clusters -- 4.3 Hierarchical Organization of Cognition -- 4.4 Experimental Analysis Methods -- 5 Conclusions -- References -- The Kindling/Sensitization Model and Early Life Stress -- 1 Introduction -- 2 Stress Sensitization -- 3 Stimulant-Induced Behavioral Sensitization -- 4 Episode-Induced Sensitization -- 5 Cross-Sensitization: Neurochemical Commonalities and Inflammatory Mechanisms -- 6 An Epigenetic Basis for Sensitization -- 7 One Genetic and Two Epigenetic Bases for Illness Vulnerability -- 8 More Stress, Episodes, and Substance Abuse in the USA Than Europe Driving Sensitization -- 9 Implications for Treatment -- 10 High Risk Children Deserve Special Attention and Treatment -- 11 Measures Considered for Primary and Secondary Prevention -- 12 Conclusions -- References -- Childhood Maltreatment in Bipolar Disorders -- 1 Introduction -- 2 Childhood Maltreatment and (More Severe) Bipolar Disorders -- 2.1 Childhood Maltreatment as a Risk Factor for Developing Bipolar Disorders -- 2.2 Childhood Maltreatment and the Severity of the Clinical Expression of Bipolar Disorders -- 2.3 Childhood Maltreatment, Psychiatric, and Medical Comorbidities in Bipolar Disorders -- 2.4 Issues About Childhood Maltreatment Subtypes, the Timing of Exposure, and Gender -- 3 Moving to Dimensions of Psychopathology in Association with Childhood Maltreatment -- 3.1 Childhood Maltreatment and Dimensions of Psychopathology in Bipolar Disorders -- 3.2 Childhood Maltreatment and Cognition in Bipolar Disorders -- 4 Childhood Maltreatment as Part of a Multiple Hit Model of Susceptibility. 4.1 Interactions Between Childhood Maltreatment and the Genetic Susceptibility to Bipolar Disorders. |
| Record Nr. | UNINA-9910485147503321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bipolar disorder / / edited by Mario Maj, [and three others]
| Bipolar disorder / / edited by Mario Maj, [and three others] |
| Pubbl/distr/stampa | Chichester, West Sussex, England : , : John Wiley & Sons, Ltd., , 2002 |
| Descrizione fisica | 1 online resource (545 p.) |
| Disciplina | 616.895 |
| Collana | WPA Series Evidence and Experience in Psychiatry |
| Soggetto topico |
Bipolar disorder
Depression, Mental |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-10127-X
9786610101276 0-470-36054-2 0-470-85176-7 0-470-84650-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
VOLUME 5 Bipolar Disorder; Contents; List of Review Contributors; Preface; CHAPTER 1 CLASSIFICATION, DIAGNOSIS AND BOUNDARIES OF BIPOLAR DISORDERS; Classification, Diagnosis and Boundaries of Bipolar Disorders: A Review; COMMENTARIES; 1.1 Terminology, History and Definition of Bipolar Spectrum; 1.2 Toward an Expansion of Bipolar Disorders in DSM-V; 1.3 Narrowing and Broadening Diagnostic Criteria for Bipolar Disorder: Competing Demands of Research and Clinical Practice; 1.4 Is Phenomenological Dissection for Bipolar Disorders Spectrum Possible?
1.5 In Search for a Definition for Bipolar Disorder1.6 What is Disordered in Bipolar Disorders?; 1.7 How Prevalent is the Bipolar Spectrum?; 1.8 Broadening the Definition of Bipolar Disorder; 1.9 Beyond Behavioural Boundaries: Redefining Mood and its Disorder Phenotype; 1.10 Towards a Unitary Framework for Mood Spectrum Beyond the Bipolar-Unipolar Dichotomy; 1.11 The Diagnosis of Bipolar Disorder: Some Open Issues; 1.12 The Bipolar Spectrum: Focus on Core Personality Characteristics 1.13 Rate of Detection and Care Utilization by People with Bipolar Disorder. Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS)1.14 Bipolar II is Bipolar, Too; 1.15 The Clinical Spectrum of Mania; 1.16 The Relevance of a Clinical Approach Towards an Earlier Diagnosis of the Bipolar Spectrum; 1.17 Syndromes, Symptoms and Spectra; 1.18 Atypical Psychosis: The Other Boundary of Bipolar Disorder; CHAPTER 2 PROGNOSIS OF BIPOLAR DISORDER; Prognosis of Bipolar Disorder: A Review; COMMENTARIES 2.1 Studies of Course and Outcome in Bipolar Disorder: What is the Real-World Clinical Significance?2.2 Understanding Outcome Differences in Bipolar Disorder; 2.3 The Effect of Affective Episodes in Bipolar Disorder; 2.4 Bipolar Disorder: A Longitudinal Perspective; 2.5 Issues in the Assessment of Course of Illness in Bipolar Disorder; 2.6 The Sustained Prospective Study: Is it Worth the Effort?; 2.7 Prognosis-When and For Whom?; 2.8 Prognosis and Manic-Depressive Cycle; 2.9 The Importance of Natural Course and Depression in Bipolar I Disorder 2.10 Analysing Course of Illness in Bipolar Disorder2.11 Outcome in Bipolar Disorder: How Much Have We Learned?; 2.12 Heterogeneity of Course and Outcome in Bipolar Disorder: Can Genetics Help?; 2.13 Chronicity, Milder Forms and Cognitive Impairment in Bipolar Disorder; 2.14 Poor Clinical Course and Suicide Risk for Bipolar Disorders; 2.15 The Role of Seasonal Changes in the Course of Bipolar Disorder; CHAPTER 3 PHARMACOLOGICAL TREATMENT OF BIPOLAR DISORDER; Pharmacological Treatment of Bipolar Disorder: A Review; COMMENTARIES 3.1 Pursuit of the Ideal Mood Stabilizer: Time to Give Up and Move to Combination Trials |
| Record Nr. | UNINA-9910142491203321 |
| Chichester, West Sussex, England : , : John Wiley & Sons, Ltd., , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bipolar disorder / / edited by Mario Maj, [and three others]
| Bipolar disorder / / edited by Mario Maj, [and three others] |
| Pubbl/distr/stampa | Chichester, West Sussex, England : , : John Wiley & Sons, Ltd., , 2002 |
| Descrizione fisica | 1 online resource (545 p.) |
| Disciplina | 616.895 |
| Collana | WPA Series Evidence and Experience in Psychiatry |
| Soggetto topico |
Bipolar disorder
Depression, Mental |
| ISBN |
1-280-10127-X
9786610101276 0-470-36054-2 0-470-85176-7 0-470-84650-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
VOLUME 5 Bipolar Disorder; Contents; List of Review Contributors; Preface; CHAPTER 1 CLASSIFICATION, DIAGNOSIS AND BOUNDARIES OF BIPOLAR DISORDERS; Classification, Diagnosis and Boundaries of Bipolar Disorders: A Review; COMMENTARIES; 1.1 Terminology, History and Definition of Bipolar Spectrum; 1.2 Toward an Expansion of Bipolar Disorders in DSM-V; 1.3 Narrowing and Broadening Diagnostic Criteria for Bipolar Disorder: Competing Demands of Research and Clinical Practice; 1.4 Is Phenomenological Dissection for Bipolar Disorders Spectrum Possible?
1.5 In Search for a Definition for Bipolar Disorder1.6 What is Disordered in Bipolar Disorders?; 1.7 How Prevalent is the Bipolar Spectrum?; 1.8 Broadening the Definition of Bipolar Disorder; 1.9 Beyond Behavioural Boundaries: Redefining Mood and its Disorder Phenotype; 1.10 Towards a Unitary Framework for Mood Spectrum Beyond the Bipolar-Unipolar Dichotomy; 1.11 The Diagnosis of Bipolar Disorder: Some Open Issues; 1.12 The Bipolar Spectrum: Focus on Core Personality Characteristics 1.13 Rate of Detection and Care Utilization by People with Bipolar Disorder. Results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS)1.14 Bipolar II is Bipolar, Too; 1.15 The Clinical Spectrum of Mania; 1.16 The Relevance of a Clinical Approach Towards an Earlier Diagnosis of the Bipolar Spectrum; 1.17 Syndromes, Symptoms and Spectra; 1.18 Atypical Psychosis: The Other Boundary of Bipolar Disorder; CHAPTER 2 PROGNOSIS OF BIPOLAR DISORDER; Prognosis of Bipolar Disorder: A Review; COMMENTARIES 2.1 Studies of Course and Outcome in Bipolar Disorder: What is the Real-World Clinical Significance?2.2 Understanding Outcome Differences in Bipolar Disorder; 2.3 The Effect of Affective Episodes in Bipolar Disorder; 2.4 Bipolar Disorder: A Longitudinal Perspective; 2.5 Issues in the Assessment of Course of Illness in Bipolar Disorder; 2.6 The Sustained Prospective Study: Is it Worth the Effort?; 2.7 Prognosis-When and For Whom?; 2.8 Prognosis and Manic-Depressive Cycle; 2.9 The Importance of Natural Course and Depression in Bipolar I Disorder 2.10 Analysing Course of Illness in Bipolar Disorder2.11 Outcome in Bipolar Disorder: How Much Have We Learned?; 2.12 Heterogeneity of Course and Outcome in Bipolar Disorder: Can Genetics Help?; 2.13 Chronicity, Milder Forms and Cognitive Impairment in Bipolar Disorder; 2.14 Poor Clinical Course and Suicide Risk for Bipolar Disorders; 2.15 The Role of Seasonal Changes in the Course of Bipolar Disorder; CHAPTER 3 PHARMACOLOGICAL TREATMENT OF BIPOLAR DISORDER; Pharmacological Treatment of Bipolar Disorder: A Review; COMMENTARIES 3.1 Pursuit of the Ideal Mood Stabilizer: Time to Give Up and Move to Combination Trials |
| Record Nr. | UNINA-9910830012403321 |
| Chichester, West Sussex, England : , : John Wiley & Sons, Ltd., , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bipolar Disorder: From Neuroscience to Treatment / Allan H. Young, Mario F. Juruena editors
| Bipolar Disorder: From Neuroscience to Treatment / Allan H. Young, Mario F. Juruena editors |
| Pubbl/distr/stampa | Cham, : Springer, 2021 |
| Descrizione fisica | VIII, 325 p. : ill. ; 24 cm |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNICAMPANIA-VAN00289046 |
| Cham, : Springer, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
| ||
Il disturbo bipolare : un approccio terapeutico cognitivo / Cory F. Newman [et al.]
| Il disturbo bipolare : un approccio terapeutico cognitivo / Cory F. Newman [et al.] |
| Edizione | [Edizione italiana a cura di A. Nisi] |
| Pubbl/distr/stampa | Roma : Fioriti editore, 2012 |
| Descrizione fisica | XII, 240p. ; 24 cm |
| Disciplina | 616.895 |
| Collana | Scienze |
| Soggetto non controllato | Disturbi bipolari |
| ISBN | 978-88-95930-58-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNINA-990009750030403321 |
| Roma : Fioriti editore, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||