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2004 2nd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, VA, 15-18 April 2004
2004 2nd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, VA, 15-18 April 2004
Pubbl/distr/stampa [Place of publication not identified], : IEEE, 2004
Disciplina 616.07/54
Soggetto topico Imaging systems in medicine
Diagnostic imaging
Image processing
Image Processing, Computer-Assisted
Methods
Diagnostic Imaging
Diagnostic Techniques and Procedures
Investigative Techniques
Computing Methodologies
Diagnosis
Information Science
Radiology, MRI, Ultrasonography & Medical Physics
Medicine
Health & Biological Sciences
Soggetto genere / forma Congress
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISA-996202124103316
[Place of publication not identified], : IEEE, 2004
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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2004 2nd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, VA, 15-18 April 2004
2004 2nd IEEE International Symposium on Biomedical Imaging--Macro to Nano : Arlington, VA, 15-18 April 2004
Pubbl/distr/stampa [Place of publication not identified], : IEEE, 2004
Disciplina 616.07/54
Soggetto topico Imaging systems in medicine
Diagnostic imaging
Image processing
Image Processing, Computer-Assisted
Methods
Diagnostic Imaging
Diagnostic Techniques and Procedures
Investigative Techniques
Computing Methodologies
Diagnosis
Information Science
Radiology, MRI, Ultrasonography & Medical Physics
Medicine
Health & Biological Sciences
Soggetto genere / forma Congress
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910872446203321
[Place of publication not identified], : IEEE, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
ADMET for Medicinal Chemists [[electronic resource] ] : A Practical Guide
ADMET for Medicinal Chemists [[electronic resource] ] : A Practical Guide
Autore Tsaioun Katya
Pubbl/distr/stampa Hoboken, : Wiley, 2012
Descrizione fisica 1 online resource (524 p.)
Disciplina 615.19
615/.19
Altri autori (Persone) KatesSteven A
Soggetto topico Drug Design
Drug Toxicity
Drugs - Testing
Drugs --Testing --Juvenile literature
Pharmaceutical Preparations - chemistry
Pharmacokinetics
Metabolic Phenomena
Drug Discovery
Pharmacological Phenomena
Natural Science Disciplines
Kinetics
Chemicals and Drugs
Poisoning
Biochemical Phenomena
Chemistry, Pharmaceutical
Substance-Related Disorders
Disciplines and Occupations
Investigative Techniques
Physiological Phenomena
Phenomena and Processes
Chemical Phenomena
Diseases
Pharmacology
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Biological Science Disciplines
Chemistry
Pharmaceutical Preparations
Health & Biological Sciences
Pharmacy, Therapeutics, & Pharmacology
ISBN 1-280-59122-6
9786613621054
0-470-91509-9
0-470-91511-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADMET for Medicinal Chemists: A Practical Guide; CONTENTS; Preface; Contributors; 1 Introduction; 1.1 Introduction; 1.2 Voyage Through The Digestive System; 1.2.1 The Mouth; 1.2.2 The Stomach; 1.2.3 The Small Intestine: Duodenum; 1.2.4 The Small and Large Intestine: Jejunum, Ileum, Colon; 1.2.5 Hepatic-Portal Vein; 1.3 The Liver Metabolism; 1.3.1 CYP450 (CYPs); 1.4 The Kidneys; 1.4.1 Active Tubular Secretion; 1.4.2 Passive Tubular Reabsorption; 1.5 Conclusions; References; 2 In Silico ADME/Tox Predictions; 2.1 Introduction; 2.2 Key Computer Methods for ADME/Tox Predictions
2.2.1 Drug Discovery2.2.2 Applying or Not ADME/Tox Predictions, Divided Opinions; 2.2.3 In Silico ADME/Tox Methods and Modeling Approaches; 2.2.4 Physicochemistry, Pharmacokinetics, Drug-Like and Lead-Like Concepts; 2.2.5 Lipophilicity; 2.2.6 pKa; 2.2.7 Transport Proteins; 2.2.8 Plasma Protein Binding; 2.2.9 Metabolism; 2.2.10 Elimination; 2.2.11 Toxicity; 2.3 Preparation of Compound Collections and Computer Programs, Challenging ADME/Tox Predictions and Statistical Methods; 2.3.1 Preparation of Compound Collections and Computer Programs
2.3.2 Preparing a Compound Collection: Materials and Methods2.3.3 Cleaning and Designing the Compound Collection; 2.3.4 Searching for Similarity; 2.3.5 Generating 3D Structures; 2.4 ADME/Tox Predictions within Pharmaceutics Companies; 2.4.1 Actelion Pharmaceuticals Ltd.; 2.4.2 Bayer; 2.4.3 Bristol-Myers Squibb; 2.4.4 Hoffmann-La Roche Ltd.; 2.4.5 Neurogen Corporation; 2.4.6 Novartis; 2.4.7 Schering AG; 2.4.8 Vertex Pharmaceuticals; 2.5 Challenging ADME/Tox Predictions; 2.5.1 Tolcapone; 2.5.2 Factor V Inhibitors; 2.5.3 CRF-1 Receptor Antagonists; 2.6 Statistical Methods
2.6.1 Principal Component Analysis2.6.2 Partial Least Square; 2.6.3 Support Vector Machine; 2.6.4 Decision Trees; 2.6.5 Neural Networks; 2.7 Conclusions; References; 3 Absorption and Physicochemical Properties of the NCE; 3.1. Introduction; 3.2. Physicochemical Properties; 3.3. Stability; 3.4. Dissolution and Solubility; 3.4.1. Dissolution Rate, Particle Size, and Solubility; 3.4.2. pH and Salts; 3.4.3. In Vivo Solubilization; 3.5. Solid State; References; 4 ADME; 4.1 Introduction; 4.2 Absorption; 4.2.1 Route of Administration; 4.2.2 Factors Determining Oral Bioavailability; 4.3 Distribution
4.3.1 Drug Distribution4.3.2 Volume of Distribution; 4.3.3 Free Drug Concentration; 4.3.4 CNS Penetration; 4.4 Elimination; 4.4.1 Elimination Versus Clearance; 4.4.2 Metabolism Versus Excretion; 4.4.3 Drug-Free Fraction and Clearance; 4.4.4 Lipophilicity and Clearance; 4.4.5 Transporters and Clearance; 4.4.6 Metabolism; 4.4.7 Excretion; 4.5 Drug Interactions; 4.5.1 Absorption-Driven DDI; 4.5.2 Distribution-Driven DDI; 4.5.3 Excretion-Driven DDI; 4.5.4 Metabolism-Driven DDI; 4.5.5 Tools for Studying Drug Metabolism; 4.5.6 Applications of Drug Metabolism Tools
4.5.7 Tools for Studying Drug Excretion
Record Nr. UNINA-9910133588303321
Tsaioun Katya  
Hoboken, : Wiley, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
ADMET for Medicinal Chemists [[electronic resource] ] : A Practical Guide
ADMET for Medicinal Chemists [[electronic resource] ] : A Practical Guide
Autore Tsaioun Katya
Pubbl/distr/stampa Hoboken, : Wiley, 2012
Descrizione fisica 1 online resource (524 p.)
Disciplina 615.19
615/.19
Altri autori (Persone) KatesSteven A
Soggetto topico Drug Design
Drug Toxicity
Drugs - Testing
Drugs --Testing --Juvenile literature
Pharmaceutical Preparations - chemistry
Pharmacokinetics
Metabolic Phenomena
Drug Discovery
Pharmacological Phenomena
Natural Science Disciplines
Kinetics
Chemicals and Drugs
Poisoning
Biochemical Phenomena
Chemistry, Pharmaceutical
Substance-Related Disorders
Disciplines and Occupations
Investigative Techniques
Physiological Phenomena
Phenomena and Processes
Chemical Phenomena
Diseases
Pharmacology
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Biological Science Disciplines
Chemistry
Pharmaceutical Preparations
Health & Biological Sciences
Pharmacy, Therapeutics, & Pharmacology
ISBN 1-280-59122-6
9786613621054
0-470-91509-9
0-470-91511-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADMET for Medicinal Chemists: A Practical Guide; CONTENTS; Preface; Contributors; 1 Introduction; 1.1 Introduction; 1.2 Voyage Through The Digestive System; 1.2.1 The Mouth; 1.2.2 The Stomach; 1.2.3 The Small Intestine: Duodenum; 1.2.4 The Small and Large Intestine: Jejunum, Ileum, Colon; 1.2.5 Hepatic-Portal Vein; 1.3 The Liver Metabolism; 1.3.1 CYP450 (CYPs); 1.4 The Kidneys; 1.4.1 Active Tubular Secretion; 1.4.2 Passive Tubular Reabsorption; 1.5 Conclusions; References; 2 In Silico ADME/Tox Predictions; 2.1 Introduction; 2.2 Key Computer Methods for ADME/Tox Predictions
2.2.1 Drug Discovery2.2.2 Applying or Not ADME/Tox Predictions, Divided Opinions; 2.2.3 In Silico ADME/Tox Methods and Modeling Approaches; 2.2.4 Physicochemistry, Pharmacokinetics, Drug-Like and Lead-Like Concepts; 2.2.5 Lipophilicity; 2.2.6 pKa; 2.2.7 Transport Proteins; 2.2.8 Plasma Protein Binding; 2.2.9 Metabolism; 2.2.10 Elimination; 2.2.11 Toxicity; 2.3 Preparation of Compound Collections and Computer Programs, Challenging ADME/Tox Predictions and Statistical Methods; 2.3.1 Preparation of Compound Collections and Computer Programs
2.3.2 Preparing a Compound Collection: Materials and Methods2.3.3 Cleaning and Designing the Compound Collection; 2.3.4 Searching for Similarity; 2.3.5 Generating 3D Structures; 2.4 ADME/Tox Predictions within Pharmaceutics Companies; 2.4.1 Actelion Pharmaceuticals Ltd.; 2.4.2 Bayer; 2.4.3 Bristol-Myers Squibb; 2.4.4 Hoffmann-La Roche Ltd.; 2.4.5 Neurogen Corporation; 2.4.6 Novartis; 2.4.7 Schering AG; 2.4.8 Vertex Pharmaceuticals; 2.5 Challenging ADME/Tox Predictions; 2.5.1 Tolcapone; 2.5.2 Factor V Inhibitors; 2.5.3 CRF-1 Receptor Antagonists; 2.6 Statistical Methods
2.6.1 Principal Component Analysis2.6.2 Partial Least Square; 2.6.3 Support Vector Machine; 2.6.4 Decision Trees; 2.6.5 Neural Networks; 2.7 Conclusions; References; 3 Absorption and Physicochemical Properties of the NCE; 3.1. Introduction; 3.2. Physicochemical Properties; 3.3. Stability; 3.4. Dissolution and Solubility; 3.4.1. Dissolution Rate, Particle Size, and Solubility; 3.4.2. pH and Salts; 3.4.3. In Vivo Solubilization; 3.5. Solid State; References; 4 ADME; 4.1 Introduction; 4.2 Absorption; 4.2.1 Route of Administration; 4.2.2 Factors Determining Oral Bioavailability; 4.3 Distribution
4.3.1 Drug Distribution4.3.2 Volume of Distribution; 4.3.3 Free Drug Concentration; 4.3.4 CNS Penetration; 4.4 Elimination; 4.4.1 Elimination Versus Clearance; 4.4.2 Metabolism Versus Excretion; 4.4.3 Drug-Free Fraction and Clearance; 4.4.4 Lipophilicity and Clearance; 4.4.5 Transporters and Clearance; 4.4.6 Metabolism; 4.4.7 Excretion; 4.5 Drug Interactions; 4.5.1 Absorption-Driven DDI; 4.5.2 Distribution-Driven DDI; 4.5.3 Excretion-Driven DDI; 4.5.4 Metabolism-Driven DDI; 4.5.5 Tools for Studying Drug Metabolism; 4.5.6 Applications of Drug Metabolism Tools
4.5.7 Tools for Studying Drug Excretion
Record Nr. UNINA-9910830164603321
Tsaioun Katya  
Hoboken, : Wiley, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in luminescence spectroscopy : a symposium
Advances in luminescence spectroscopy : a symposium
Pubbl/distr/stampa [Place of publication not identified], : ASTM, 1985
Disciplina 543/.0858
Altri autori (Persone) Cline LoveL. J
EastwoodD
Soggetto topico Photometry
Chemistry Techniques, Analytical
Investigative Techniques
Diagnostic Techniques and Procedures
Luminescent Measurements
Spectrum Analysis
ISBN 0-8031-4928-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910164709703321
[Place of publication not identified], : ASTM, 1985
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Advances in small animal total joint replacement / / edited by Jeffrey N. Peck, Denis J. Marcellin-Little
Advances in small animal total joint replacement / / edited by Jeffrey N. Peck, Denis J. Marcellin-Little
Pubbl/distr/stampa Chichester, : Wiley-Blackwell, 2013
Descrizione fisica 1 online resource (xix, 251 pages) : some col. ill
Disciplina 636.089705
Altri autori (Persone) PeckJeffrey N
Marcellin-LittleDenis J <1964-> (Denis Jacques)
Collana AVS Advances in Veterinary Surgery
Soggetto topico Arthroplasty
Pets - Health
Veterinary surgery
Prosthesis Implantation
Investigative Techniques
Animals, Domestic
Veterinary Medicine
Health Occupations
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Orthopedic Procedures
Animal Population Groups
Surgical Procedures, Operative
ISBN 1-118-70477-0
1-283-64426-6
1-118-46271-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910141378903321
Chichester, : Wiley-Blackwell, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in small animal total joint replacement / / edited by Jeffrey N. Peck, Denis J. Marcellin-Little
Advances in small animal total joint replacement / / edited by Jeffrey N. Peck, Denis J. Marcellin-Little
Pubbl/distr/stampa Chichester, : Wiley-Blackwell, 2013
Descrizione fisica 1 online resource (xix, 251 pages) : some col. ill
Disciplina 636.089705
Altri autori (Persone) PeckJeffrey N
Marcellin-LittleDenis J <1964-> (Denis Jacques)
Collana AVS Advances in Veterinary Surgery
Soggetto topico Arthroplasty
Pets - Health
Veterinary surgery
Prosthesis Implantation
Investigative Techniques
Animals, Domestic
Veterinary Medicine
Health Occupations
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Orthopedic Procedures
Animal Population Groups
Surgical Procedures, Operative
ISBN 1-118-70477-0
1-283-64426-6
1-118-46271-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910830143503321
Chichester, : Wiley-Blackwell, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
AIDS [[electronic resource]]
AIDS [[electronic resource]]
Autore Aggleton Peter
Pubbl/distr/stampa Hoboken, : Taylor and Francis, 1995
Descrizione fisica 1 online resource (237 p.)
Disciplina 362.1/969792
Altri autori (Persone) DaviesPeter (Peter M.)
HartGraham <1957->
Collana Social Aspects of AIDS
Soggetto topico AIDS (Disease)
AIDS (Disease) - Social aspects
HIV Infections
Sociology
Slow Virus Diseases
Probability
Acquired Immunodeficiency Syndrome
Risk
Social Environment
Virus Diseases
Statistics as Topic
Lentivirus Infections
Sexually Transmitted Diseases, Viral
Mathematical Concepts
Social Sciences
Immunologic Deficiency Syndromes
Phenomena and Processes
Sexually Transmitted Diseases
Anthropology, Education, Sociology and Social Phenomena
Diseases
Health Care Evaluation Mechanisms
Retroviridae Infections
Immune System Diseases
Epidemiologic Methods
Quality of Health Care
Investigative Techniques
Public Health
RNA Virus Infections
Environment and Public Health
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Health Care Quality, Access, and Evaluation
Health Care
Communicable Diseases
Health & Biological Sciences
Soggetto genere / forma Electronic books.
ISBN 9982-19-047-4
0-203-36253-5
1-135-74692-3
1-280-02179-9
9786610021796
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Book Cover; Title; Contents; Preface; Reputedly Effective Risk Reduction Strategies and Gay Men; HIV-Related Discrimination in Medical Teaching Texts; Travel, Sexual Behaviour and Gay Men; Sexual Behaviour in Gay Men: Towards a Sociology of Risk; Framing Difference: Sexuality, AIDS and Organization; Towards Effective Inter vention: Evaluating HIV Prevention and Sexual Health Education Interventions; Communities, Governments and AIDS: Making Partnerships Work; Socially Apart Youth: Priorities for HIV Prevention
Theorizing and Researching 'Risk': Notes on the Social Relations of Risk in Heroin Users' LifestylesSex, Love and Seropositivity: Balancing the Risks; One of Us, One of Them, or One of Those? The Construction of Identity and Sexuality in Relation to HIV/AIDS; Sexuality, Identity and Community; Reflections on the MESMAC Project; Discourses of Power and Empowerment in the Fight Against HIV/AIDS in Africa; Notes on Contributors; Index
Record Nr. UNISA-996207278803316
Aggleton Peter  
Hoboken, : Taylor and Francis, 1995
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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AIDS : the making of a chronic disease
AIDS : the making of a chronic disease
Pubbl/distr/stampa [Place of publication not identified], : University of California Press, 1992
Disciplina 614.5/993
Soggetto topico AIDS (Disease) - History
Financial Support
Health Personnel
Homosexuality
Mass Media
Social Control, Formal
State Government
Substance-Related Disorders
Blood Donors
Confidentiality
Delivery of Health Care
Government
Acquired Immunodeficiency Syndrome
Blood Transfusion
Education
History
Legislation
Local Government
Health Policy
Hemophilia A
Human Experimentation
Jurisprudence
Public Health
Minority Groups
Federal Government
Government Regulation
HIV Seropositivity
Public Policy
International Cooperation
Developing Countries
Chronic Disease
Women
Politics
AIDS Serodiagnosis
Ethics, Medical
Internationality
Pharmaceutical Preparations
Employment
Poverty
Prejudice
Epidemiology
Publication Formats
Patient Care Management
Tissue Donors
Environment and Public Health
Economics
Health Care Facilities, Manpower, and Services
Medicine
Patient Rights
Forensic Psychiatry
Diseases
Health
Sociology
Disease Attributes
Persons
HIV Infections
Blood Coagulation Disorders, Inherited
Social Control Policies
Health Care Quality, Access, and Evaluation
Investigative Techniques
Biological Therapy
Serologic Tests
Organizations
Social Sciences
Sexuality
Coagulation Protein Disorders
Anthropology, Education, Sociology and Social Phenomena
Humanities
Psychology, Social
Social Problems
Hemorrhagic Disorders
Socioeconomic Factors
Health Care Economics and Organizations
Chemicals and Drugs
Ethics, Clinical
Research
Slow Virus Diseases
Occupational Groups
Biomedical Research
Communications Media
Mental Disorders
Health Care
Genetic Diseases, Inborn
Policy
Behavior and Behavior Mechanisms
Immunologic Deficiency Syndromes
Human Rights
Immunologic Tests
Science
Sexually Transmitted Diseases, Viral
Population Characteristics
Therapeutics
Virus Diseases
Psychiatry and Psychology
Publication Characteristics
Sexual Behavior
Psychiatry
Reproductive Physiological Phenomena
Health Services Administration
Named Groups
Information Science
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Ethics, Professional
Blood Coagulation Disorders
Pathologic Processes
Lentivirus Infections
Hematologic Diseases
Health Occupations
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Ethics
Immunologic Techniques
Sexually Transmitted Diseases
Immune System Diseases
Laboratory Techniques and Procedures
Behavior
Pathological Conditions, Signs and Symptoms
Retroviridae Infections
Hemic and Lymphatic Diseases
Reproductive and Urinary Physiological Phenomena
Natural Science Disciplines
Disciplines and Occupations
Behavioral Sciences
RNA Virus Infections
Diagnosis
Phenomena and Processes
Behavioral Disciplines and Activities
Communicable Diseases
Health & Biological Sciences
ISBN 0-520-07569-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti AIDS
Record Nr. UNINA-9910495891403321
[Place of publication not identified], : University of California Press, 1992
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Alcohol consumption and cancer risk : understanding possible causal mechanisms for breast and colorectal cancers
Alcohol consumption and cancer risk : understanding possible causal mechanisms for breast and colorectal cancers
Pubbl/distr/stampa [Place of publication not identified], : Agency for Healthcare Research and Quality, 2010
Descrizione fisica 1 online resource (ix, 81 p.)
Collana AHRQ Publication
Evidence Report/Technology Assessment
Soggetto topico Risk
Breast Diseases
Drinking Behavior
Colonic Diseases
Intestinal Neoplasms
Causality
Neoplasms by Site
Rectal Diseases
Gastrointestinal Neoplasms
Neoplasms
Probability
Intestinal Diseases
Behavior
Epidemiologic Factors
Skin Diseases
Diseases
Behavior and Behavior Mechanisms
Gastrointestinal Diseases
Statistics as Topic
Skin and Connective Tissue Diseases
Digestive System Neoplasms
Quality of Health Care
Public Health
Digestive System Diseases
Environment and Public Health
Epidemiologic Methods
Health Care Quality, Access, and Evaluation
Health Care Evaluation Mechanisms
Health Care
Investigative Techniques
Diagnostic Techniques and Procedures
Breast Neoplasms
Risk Factors
Colorectal Neoplasms
Alcohol Drinking
Medicine
Health & Biological Sciences
Oncology
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910703239203321
[Place of publication not identified], : Agency for Healthcare Research and Quality, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui

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