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The 7 sexes [[electronic resource] ] : biology of sex determination / / Elof Axel Carlson
The 7 sexes [[electronic resource] ] : biology of sex determination / / Elof Axel Carlson
Autore Carlson Elof Axel
Pubbl/distr/stampa Bloomington, : Indiana University Press, c2013
Descrizione fisica 1 online resource (256 p.)
Disciplina 612.6
Soggetto topico Sex determination, Genetic
Gene expression
Soggetto genere / forma Electronic books.
ISBN 1-283-94962-8
0-253-00654-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; List of Tables; List of Figures; Preface; 1 Introduction; 2 Wild Guesses in an Era of Scientific Ignorance; 3 The Ancient World; 4 Monotheistic Religious Interpretations; 5 The Descriptive Embryology of Male and Female Development; 6 The Discovery of the Egg in Higher Eukaryotes; 7 The Discovery of Sperm in Higher Eukaryotes; 8 The Discovery of Sex Hormones; 9 Ploidy Levels and Sex Determination; 10 The Discovery of Sex Chromosomes; 11 The Balance Theory of Sex Determination; 12 The Discovery of Sex in Microorganisms
13 The History and Interpretations of Hermaphrodites and Intersexes14 Dosage Compensation and the Sex Chromosomes; 15 The Discovery of Human Sex Chromosome Conditions; 16 The Seven Sexes of Humans; 17 The Identification and Role of Sex-Determining Genes; 18 The History of Homosexuality; 19 The History of Behavioral Gender Assignment; 20 The Evolution of Sex Determination; 21 What Does It Mean to Have an Assigned Sex?; 22 The Quest for a Unified Theory of Sex, Gender, and Sexuality; Afterword; Appendix: Secondary Literature and the Relation of Biology to Sex and Gender; Glossary; A; B; C; D; E
FG; H; I; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z; Notes; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910462593503321
Carlson Elof Axel  
Bloomington, : Indiana University Press, c2013
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The 7 sexes [[electronic resource] ] : biology of sex determination / / Elof Axel Carlson
The 7 sexes [[electronic resource] ] : biology of sex determination / / Elof Axel Carlson
Autore Carlson Elof Axel
Pubbl/distr/stampa Bloomington, : Indiana University Press, c2013
Descrizione fisica 1 online resource (256 p.)
Disciplina 612.6
Soggetto topico Sex determination, Genetic
Gene expression
Soggetto genere / forma Electronic books.
ISBN 1-283-94962-8
0-253-00654-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; List of Tables; List of Figures; Preface; 1 Introduction; 2 Wild Guesses in an Era of Scientific Ignorance; 3 The Ancient World; 4 Monotheistic Religious Interpretations; 5 The Descriptive Embryology of Male and Female Development; 6 The Discovery of the Egg in Higher Eukaryotes; 7 The Discovery of Sperm in Higher Eukaryotes; 8 The Discovery of Sex Hormones; 9 Ploidy Levels and Sex Determination; 10 The Discovery of Sex Chromosomes; 11 The Balance Theory of Sex Determination; 12 The Discovery of Sex in Microorganisms
13 The History and Interpretations of Hermaphrodites and Intersexes14 Dosage Compensation and the Sex Chromosomes; 15 The Discovery of Human Sex Chromosome Conditions; 16 The Seven Sexes of Humans; 17 The Identification and Role of Sex-Determining Genes; 18 The History of Homosexuality; 19 The History of Behavioral Gender Assignment; 20 The Evolution of Sex Determination; 21 What Does It Mean to Have an Assigned Sex?; 22 The Quest for a Unified Theory of Sex, Gender, and Sexuality; Afterword; Appendix: Secondary Literature and the Relation of Biology to Sex and Gender; Glossary; A; B; C; D; E
FG; H; I; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z; Notes; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910527289403321
Carlson Elof Axel  
Bloomington, : Indiana University Press, c2013
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Advances in Synthetic Biology [[electronic resource] /] / edited by Vijai Singh
Advances in Synthetic Biology [[electronic resource] /] / edited by Vijai Singh
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (XIII, 349 p. 75 illus., 63 illus. in color.)
Disciplina 660.6
Soggetto topico Systems biology
Genetic engineering
Gene expression
Medical genetics
Electronic circuits
Bioenginyeria
Expressió gènica
Enginyeria biomèdica
Systems Biology
Genetic Engineering
Gene Expression
Gene Function
Circuits and Systems
Soggetto genere / forma Llibres electrònics
ISBN 981-15-0081-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. Introduction to Synthetic Biology -- Chapter 2. Current progress in synthetic genetic networks -- Chapter 3. Current Progress and Limitations in the Design, Construction and Characterization of Synthetic Parts -- Chapter 4. Recent progress in DNA parts standardization and characterization -- Chapter 5. Current status and challenges of DNA sequencing -- Chapter 6. Biomimetic approaches in synthetic biology -- Chapter 7. Design principles of synthetic biological oscillators -- Chapter 8. SOFTWARE-AIDED DESIGN OF IDEALISED PROGRAMMABLE NUCLEIC ACID CIRCUITS -- Chapter 9. Digital Circuit Design for Biological and Silicon Computers -- Chapter 10. Engineering of riboregulators for gene regulation as a tool for synthetic biology -- Chapter 11. Recent advances, challenges and opportunities in riboswitches -- Chapter 12. Recent Advances in Gene and Genome Assembly: Challenges and Implications -- Chapter 13. Recent advances, challenges and opportunities in synthetic genomes -- Chapter 14. Expansion of the genetic code -- Chapter 15. Expanding the potential of CRISPR-Cas9 technology for crops improvement -- Chapter 16. Synthetic biology at the hand of cell-free systems -- Chapter 17. Synthetic Biology for the Rapid, Precise and Compliant Detection of Microbes -- Chapter 18. Application and challenges of synthetic biology -- Chapter 19. Development and Application of Microfluidics in Synthetic Biology -- Chapter 20. The Ethics of Synthetic Biology Research and Development: A Principlist Approach. .
Record Nr. UNINA-9910409699303321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020
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Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Analysing gene expression [[electronic resource] ] : a handbook of methods: possibilities and pitfalls / / edited by Stefan Lorkowski and Paul Cullen
Pubbl/distr/stampa Weinheim ; ; New York, : Wiley-VCH, c2003
Descrizione fisica 1 online resource (984 p.)
Disciplina 572.8/65
572.865
Altri autori (Persone) LorkowskiStefan
CullenPaul, Dr.
Soggetto topico Gene expression
Soggetto genere / forma Electronic books.
ISBN 1-280-52042-6
9786610520428
3-527-60533-9
3-527-60149-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Analysing Gene Expression A Handbook of Methods Possibilities and Pitfalls; Foreword; Preface; Contents; List of Contributors; Volume 1; 1 Basic concepts of gene expression; 1.1 Introduction; 1.2 Basics of transcription and translation in the cell; 1.2.1 Introduction; 1.2.2 Transcription; 1.2.3 Translation; 1.2.4 Summary; 1.3 Regulation of transcription; 1.3.1 Introduction; 1.3.2 mRNA expression profiles - the transcriptome; 1.3.3 Protein expression profiles - the proteome; 1.3.4 Interaction between genes and proteins - the interactome; 1.3.5 The transcription machinery and core promoters
1.3.6 Regulatory promoters1.3.7 Enhancers; 1.3.8 Locus control regions; 1.3.9 Matrix attachment regions; 1.3.10 Insulators; 1.3.11 RIDGEs - Regions of increased gene expression; 1.3.12 Enhanceosomes; 1.3.13 Chromatin; 1.3.14 Silencer elements; 1.3.15 Transcription factors, repressors and co-repressors; 1.3.16 Epigenetics; 1.3.17 Summary and conclusions; 1.4 Post-transcriptional regulation; 1.4.1 Introduction; 1.4.2 Regulation of RNA stability and degradation; 1.4.3 Regulation of transcription elongation; 1.4.3.1 Introduction; 1.4.3.2 Regulation of transcription elongation in prokaryotes
1.4.3.3 Regulation of transcription elongation in eukaryotes1.4.3.4 Conclusions; 1.4.4 Differential/alternative pre-mRNA splicing; 1.4.5 Trans-RNA splicing; 1.4.6 Regulation of mRNA transport; 1.4.7 Directed intracellular mRNA localisation; 1.4.8 Regulation of mRNA polyadenylation; 1.4.9 Antisense RNA; 1.4.10 RNA editing; 1.4.11 Summary and conclusions; 1.5 Post-translational modification of proteins; 1.5.1 Introduction; 1.5.2 Proteolytic cleavage of proteins; 1.5.3 Acylation; 1.5.4 Prenylation; 1.5.5 Methylation; 1.5.6 Sulphation; 1.5.7 Phosphorylation; 1.5.8 Ubiquitination
1.5.9 Glycosylation1.5.10 Conclusions; 1.6 Correlation of mRNA and protein expression; 1.6.1 Introduction; 1.6.2 Levels of mRNA and protein expression: correlations and discrepancies; 1.6.3 Conclusions; 1.7 Housekeeping genes, internal and external standards; 1.7.1 What are housekeeping genes?; 1.7.2 Survey of the most important housekeeping genes; 1.7.2.1 Glyceraldehyde-3-phosphate dehydrogenase; 1.7.2.2 β-Actin; 1.7.3 Other commonly used housekeeping genes; 1.7.3.1 Ribosomal RNA (rRNA); 1.7.4 New identified 'maintenance genes'; 1.7.5 Methods of quantification
1.7.5.1 Normalisation (via internal standards)1.7.5.2 Standard curves (via external standards); 1.7.5.3 Alternative methods (via internal standards); 1.7.6 Summary; 1.8 Classification of differential gene expression technologies; 1.8.1 Introduction; 1.8.2 From single genes to transcriptomes; 1.8.3 Methods of classification; 1.8.4 Conclusions; 1.9 Summary; 1.10 References; 2 Sample preparation and supplementary tools; 2.1 Introduction; 2.2 Preparation of cells and tissues; 2.2.1 Immunopurification of cells; 2.2.2 Differential-velocity centrifugation/countercurrent elutriation
2.2.3 Surface affinity chromatography
Record Nr. UNINA-9910146242103321
Weinheim ; ; New York, : Wiley-VCH, c2003
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Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays [[electronic resource] /] / by Mehmet Eren Ahsen, Hitay Özbay, Silviu-Iulian Niculescu
Analysis of Deterministic Cyclic Gene Regulatory Network Models with Delays [[electronic resource] /] / by Mehmet Eren Ahsen, Hitay Özbay, Silviu-Iulian Niculescu
Autore Ahsen Mehmet Eren
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Birkhäuser, , 2015
Descrizione fisica 1 online resource (104 p.)
Disciplina 576.5
Collana SpringerBriefs in Control, Automation and Robotics
Soggetto topico System theory
Biomathematics
Gene expression
Control engineering
Robotics
Mechatronics
Systems Theory, Control
Mathematical and Computational Biology
Gene Expression
Control, Robotics, Mechatronics
ISBN 3-319-15606-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Introduction -- Basic Tools from Systems and Control Theory -- Functions with Negative Schwarzian Derivatives -- Deterministic ODE-Based Model with Time Delay -- Gene Regulatory Networks under Negative Feedback -- Gene Regulatory Networks under Positive Feedback -- Summary and Concluding Remarks -- References.
Record Nr. UNINA-9910299699303321
Ahsen Mehmet Eren  
Cham : , : Springer International Publishing : , : Imprint : Birkhäuser, , 2015
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Arterial Chemoreceptors in Physiology and Pathophysiology [[electronic resource] /] / edited by Chris Peers, Prem Kumar, Christopher Wyatt, Estelle Gauda, Colin A. Nurse, Nanduri Prabhakar
Arterial Chemoreceptors in Physiology and Pathophysiology [[electronic resource] /] / edited by Chris Peers, Prem Kumar, Christopher Wyatt, Estelle Gauda, Colin A. Nurse, Nanduri Prabhakar
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (390 p.)
Disciplina 599.0188
Collana Advances in Experimental Medicine and Biology
Soggetto topico Human physiology
Pharmacology
Laboratory medicine
Gene expression
Molecular biology
Neurosciences
Human Physiology
Pharmacology/Toxicology
Laboratory Medicine
Gene Expression
Molecular Medicine
ISBN 3-319-18440-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- C Peers & P Kumar -- 2 Epigenetic regulation of Carotid Body Oxygen Sensing: Clinical Implications, J. Nanduri, N. R. Prabhakar -- 3 Experimental observations on the biological significance of hydrogen sulfide in carotid body chemoreception, T.Gallego-Martin, T. Agapito, M. Ramirez, E. Olea, S. Yubero, A. Rocher, A. Gomez-Nino, A. Obeso, C. Gonzalez -- 4 The CamKKβ inhibitor STO609 causes artefacts in calcium imaging and selectively inhibits BKCa in mouse carotid body type I cells -- J. G. Jurcsisn, R. L. Pye, J. Ali, B. L. Barr and C. N. Wyatt -- 5 Tissue dynamics of the carotid body under chronic hypoxia: a computational study, A. Porzionato, D. Guidolin, V. Macchi, G. Sarasin, A. Mazzatenta, C. Di Giulio, J. Lopez-Barneo, R. De Caro -- 6 Paracrine Signaling in Glial-like Type II cells of the Rat Carotid Body, S. Murali, M. Zhang, C. A. Nurse -- 7 Selective μ and κ opioid agonists inhibit voltage-gated Ca2+ entry in isolated rat carotid body type I cells, E. M. Ricker, R. L. Pye, B. L. Barr, C. N. Wyatt -- 8 Measurement of ROS levels and membrane potential dynamics in the intact carotid body ex vivo, A. Bernardini, U. Brockmeier, E. Metzen, U. Berchner-Pfannschmidt, E. Harde, A. Acker-Palmer, D. Papkovsky, H. Acker, J. Fandrey -- 9 Acutely administered leptin increases [Ca2+]i and changes membrane conductance via modulation of BKCa channels in rat carotid body type I cells, R.L. Pye, E.J. Dunn, E.M. Ricker, B.L. Barr, C.N. Wyatt -- 10 Functional properties of mitochondria in the type-1 cell and their role in oxygen sensing, K.J. Buckler & P.J. Turner -- 11 Potentiation of hypoxic pulmonary vasoconstriction by hydrogen sulfide precursors 3-mercaptopyruvate and D-cysteine is blocked by the cystathione g lyase inhibitor propargylglycine, J. Prieto-Lloret & P. I. Aaronson -- 12 Modulation of the LKB1-AMPK signalling pathway underpins hypoxic pulmonary vasoconstriction and pulmonary hypertension, A.M. Evans, S.A. Lewis, O.A. Ogunbayo, J. Moral-Sanz -- 13 Organismal Responses to Hypoxemic Challenges, R.S. Fitzgerald, G.A. Dehghani, S. Kiihl -- 14 Effect of lipopolysacchride (LPS) exposure on structure and function of the carotid body in newborn rats, Z.R. Master, K. Kesavan, A. Mason, M. Shirahata, E.B. Gauda -- 15 Hypoxic Ventilatory Reactivity in Experimental Diabetes, M. Pokorski, M. Pozdzik, J. Antosiewicz, A. Dymecka, A. Mazzatenta, C. Di Giulio -- 16 Adenosine receptor blockade by caffeine inhibits carotid sinus nerve chemosensory activity in chronic intermittent hypoxic animals, J.F. Sacramento, C. Gonzalez,  M.C. Gonzalez-Martin and S.V. Conde -- 17 Neurotrophic properties, chemosensory responses and neurogenic niche of the human carotid body, P Ortega-Sáenz, J Villadiego, R Pardal, JJ Toledo-Aral and J López-Barneo -- 18 Is the carotid body a metabolic monitor?, M. Shirahata, W-Y Tang, M.-K. Shin, V. Polotsky -- 19 Lipopolysaccharide-induced ionized hypocalcemia and acute kidney injury in carotid chemo/baro-denervated rats, R. Fernandez, P. Cortes, R. del Rio, C. Acuna-Castillo, E.P. Reyes -- 20 Role of the Carotid Body Chemoreflex in the Pathophysiology of Heart Failure: A Perspective from Animal Studies, H.D. Schultz, N. J. Marcus & R. Del Rio -- 21 A short-term fasting in neonates induces breathing instability and epigenetic modification in the carotid body, W.-Y. Tang, E. Kostuk, M. Shirahata -- 22 Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla, G.K. Kumar, Y-J. Peng, J. Nanduri, N.R. Prabhakar -- 23 The association between antihypertensive medication and blood pressure control in patients with obstructive sleep apnea, L.N. Diogo, P. Pinto, C. Bárbara, A.L. Papoila, E.C. Monteiro -- 24 An overview on the respiratory stimulant effects of caffeine and progesterone on response to hypoxia and apnea frequency in developing rats, A. Bairam, N.P. Uppari, S. Mubayed, V. Joseph -- 25 Hyperbaric oxygen therapy improves glucose homeostasis in type 2 diabetes patients: a likely involvement of the carotid bodies, P. Vera-Cruz, F. Guerreiro,  M.J. Ribeiro, M.P. Guarino, S.V. Conde -- 26 Possible role of TRP channels in rat glomus cells, I. Kim, L. Fite, D. F. Donnelly, J. H. Kim, J. L. Carroll -- 27 Nitric oxide deficit is part of the maladaptive paracrine-autocrine response of the carotid body to intermittent hypoxia in sleep apnea, M.L. Fung -- 28 Respiratory control in the mdx mouse model of Duchenne muscular dystrophy , D. Burns, D. Edge, D. O’Malley, K.D. O’Halloran -- 29 Mild chronic intermittent hypoxia in Wistar rats evokes significant cardiovascular pathophysiology but no overt changes in carotid body-mediated respiratory responses, C. J. Ray, B. Dow, P. Kumar, A.M. Coney -- 30 Crucial role of the carotid body chemoreceptors on the development of high arterial blood pressure during chronic intermittent hypoxia, R. Iturriaga, D.C. Andrade, R. Del Rio -- 31 Relative contribution of nuclear and membrane progesterone receptors in respiratory control, R. Boukari, F. Marcouiller, V. Joseph -- 32 Inhibition of protein kinases AKT and ERK1/2 reduce the carotid body chemoreceptor response to hypoxia in adult rats, J. P. Iturri, V. Joseph, G. Rodrigo, A. Bairam, J. Soliz -- 33  Ecto-5’-nucleotidase, adenosine and transmembrane adenylyl cyclase signalling regulate basal carotid body chemoafferent outflow and establish the sensitivity to hypercapnia, A.P.S. Holmes, A.R. Nunes, M.J. Cann, P.Kumar -- 34 T-type Ca2+ channel regulation by CO: a mechanism for control of cell proliferation, H. Duckles, M.M. Al-Owais, J. Elies, E. Johnson, H.E. Boycott, M.L. Dallas, K.E. Porter, J.P. Boyle, J. L. Scragg, C. Peers -- 35 Glutamatergic Receptor Activation in the Commisural Nucleus Tractus Solitarii (cNTS) Mediates Brain Glucose Retention (BGR) Response to Anoxic Carotid Chemoreceptor (CChr) Stimulation in Rats, R. Cuellar, S. Montero, S. Luquin, J. Garcia-Estrada, O. Dobrovinskaya, V. Melnikov, M. Lemus, E. Roces de Alvarez-Buyll -- 36 Enhanced Serotonin (5HT) secretion in pulmonary neuroepithelial bodies from PHD-1 null mice, S. Livermore, J. Pan, H. Yeger, P. Ratcliffe, T. Bishop, E. Cutz -- 37 Selective expression of galanin in type I cells of the human carotid body, C. Di Giulio, G.D. Marconi, S. Zara, A. Di Tano, A. Porzionato, M. Pokorski, A. Cataldi, V. Macchi , A.Mazzatenta -- 38 Role of BK channels in murine carotid body neural responses in vivo, L.E. Pichard, C.M. Crainiceanu, P. Pashai, E.W. Kostuk, A. Fujioka, M. Shirahata -- 39 Chronic intermittent hypoxia blunts the expression of ventilatory long term facilitation in sleeping rats, D. Edge, KD. O’Halloran -- 40 Heme oxygenase-1 influences apoptosis via CO-mediated inhibition of K+ channels, M.M. Al-Owais, M.L. Dallas, J.P. Boyle, J. L. Scragg , C. Peers -- 41 Inhibition of T-type Ca2+ channels by hydrogen sulphide, J. Elies, JL Scragg, M. Dallas, D. Huang, S. Huang, JP Boyle, N. Gamper, C. Peers -- 42 GAL-021 and GAL-160 are efficacious in rat models of obstructive and central sleep apnea and inhibit BKCa in isolated rat carotid body glomus cells, M. Dallas, C. Peers, F.J. Golder, S. Baby, R. Grube, D.E. MacIntyre -- 43 The human carotid body gene expression and function in signaling of hypoxia and inflammation, J. Kåhlin, S. Mkrtchian, A. Ebberyd, L. I. Eriksson, M. J. Fagerlund -- 44 The Carotid Body Does Not Mediate The Acute Ventilatory Effects Of Leptin, E. Olea, M.J. Ribeiro, T.Gallego-Martin,  S. Yubero, R. Rigual,  JF. Masa, A. Obeso, S. V. Conde, C. Gonzalez -- 45 Concluding Remarks, E. Gauda -- Index.
Record Nr. UNINA-9910298459303321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
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Bacteriophage Applications - Historical Perspective and Future Potential [[electronic resource] /] / by Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev
Bacteriophage Applications - Historical Perspective and Future Potential [[electronic resource] /] / by Jessica Nicastro, Shirley Wong, Zahra Khazaei, Peggy Lam, Jonathan Blay, Roderick A. Slavcev
Autore Nicastro Jessica
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (VII, 82 p.)
Disciplina 576.6482
Collana SpringerBriefs in Biochemistry and Molecular Biology
Soggetto topico Biochemical engineering
Combinatorial chemistry
Gene expression
Biochemical Engineering
Combinatorial Libraries
Gene Expression
ISBN 9783319457918
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Introduction: What are Bacteriophage: a. Discovery and early phage work (including work with bacterial genetics, phage display, and phage therapy) -- b. Bacteriophage pathogenesis and host range -- c. Bacteriophage growth dynamics -- d. Bacteriophage pharmacokinetics( including mammalian host tolerance ) -- 2. Applications with Bacteriophage: a. Phage Therapy -- i. Past – why phage therapy was unsuccessful in the past and what can (and is currently) being done to improve the system -- ii. Present /Future – current research objectives and future considerations -- Host range and how it can be expanded -- Lethal agent delivery systems (bacteriocidial) -- Lethality without lysis -- b. Phage Vaccines and Phage Immunostimulation -- i. Mammalian immune response to phage -- ii. Phage vaccine delivery vehicles -- iii. Phage Immunotherapy -- c. Phage as Delivery Vehicles: i. Phage for gene delivery -- Phage display for specific cell targeting -- Considerations for use and benefits in comparison to current systems -- ii. Phage as Drug Carriers -- Selectivity and cell attachment -- Phage T2 as a potential cancer therapeutic -- Phage for delivery to the brain and CNS (including current work with Alzheimer’s and drug addictions ) -- d. Phage for Bacterial Detection: i. History of Phage bacterial detection -- ii. Methods (replication assays, conjugation with bioluminescence, labelling etc. ) -- iii. Potential uses in healthcare and industry -- e. Phage for the targeting of Biofilms -- i. Phage candidates and important bacterial targets -- ii. History and potential uses in healthcare and industry -- f. Phage device coatings: i. Current phage coating practices and research -- ii. Callenges (notably phage orientation) -- iii. methods to overcome these challenges.
Record Nr. UNINA-9910254050703321
Nicastro Jessica  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
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Basics of Bioinformatics [[electronic resource] ] : Lecture Notes of the Graduate Summer School on Bioinformatics of China / / edited by Rui Jiang, Xuegong Zhang, Michael Q. Zhang
Basics of Bioinformatics [[electronic resource] ] : Lecture Notes of the Graduate Summer School on Bioinformatics of China / / edited by Rui Jiang, Xuegong Zhang, Michael Q. Zhang
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (410 p.)
Disciplina 570.285
Soggetto topico Bioinformatics
Gene expression
Data mining
Statistics 
Computational Biology/Bioinformatics
Gene Expression
Data Mining and Knowledge Discovery
Statistics for Life Sciences, Medicine, Health Sciences
ISBN 3-642-38951-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Basics for Bioinformatics -- Basic Statistics for Bioinformatics -- Topics in Computational Genomics -- Statistical Methods in Bioinformatics -- Algorithms in Computational Biology -- Multivariate Statistical Methods in Bioinformatics Research -- Association Analysis for Human Diseases: Methods and Examples -- Data Mining and Knowledge Discovery Methods with Case Examples -- Applied Bioinformatics Tools -- Foundations for the Study of Structure and Function of Proteins -- Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine -- Advanced Topics in Bioinformatics and Computational Biology.
Record Nr. UNINA-9910437581403321
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
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Basics of Human Andrology [[electronic resource] ] : A Textbook / / edited by Anand Kumar, Mona Sharma
Basics of Human Andrology [[electronic resource] ] : A Textbook / / edited by Anand Kumar, Mona Sharma
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XIX, 536 p. 160 illus., 110 illus. in color.)
Disciplina 612.61
Soggetto topico Human physiology
Cell biology
Endocrinology 
Andrology
Gene expression
Human Physiology
Cell Biology
Endocrinology
Gene Expression
ISBN 981-10-3695-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. The Human Y Chromosome -- Chapter 2. Development of Gonads and Accessory Sex Glands -- Chapter 3. The Testis -- Chapter 4 -- Prostate -- Chapter 5. Seminal Vesicles -- Chapter 6. Genital Ducts & Other Accessory Sex Glands -- Chapter 7. Neurovascular Supply and Lymphatic Drainage of Male Reproductive Organs -- Chapter 8 -- Hypothalamo-Hypophyseal Testicular Axis -- Chapter 9. Testicular Hormones -- Chapter 10. Spermatogenesis. Chapter 11 -- The Human Semen. Chapter 12 -- The Basis of Sperm Function Tests -- Chapter 13 -- Male Puberty -- Chapter 14 -- Male Sexual Function. Chapter 15 -- Brain Areas Regulating Behavior -- Chapter 16. Neural Pathways of Behavior -- Chapter 17. Brain Sexual Dimorphism -- Chapter 18. Immunology of Male Reproductive System -- Chapter 19. Male Ageing and Andropause -- Chapter 20. Primary Testicular Failure -- Chapter 21. Biology of Male Hermaphrodite and Intersex -- Chapter 22. Thyroid and Male Reproduction -- Chapter 23. Metabolic Disorders and Male Reproduction -- Chapter 24. Gynecomastia -- Chapter 25. Male Contraception and Endocrine Disrupters.
Record Nr. UNINA-9910253930603321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017
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The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level [[electronic resource] /] / edited by Mary Ann Asson-Batres, Cécile Rochette-Egly
The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level [[electronic resource] /] / edited by Mary Ann Asson-Batres, Cécile Rochette-Egly
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (233 p.)
Disciplina 615.5
Collana Subcellular Biochemistry
Soggetto topico Medicine
Gene expression
Nutrition   
Medicine 
Health
Biomedicine, general
Gene Expression
Science, Humanities and Social Sciences, multidisciplinary
Nutrition
Medicine/Public Health, general
Popular Science in Medicine and Health
ISBN 94-017-9050-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Forward -- History of Retinoic Acid Receptors -- Architecture of DNA Bound RAR Heterodimers -- Retinoic Acid Receptors: Structural Basis for Coregulator Interaction and Exchange -- Evolution of Retinoic Acid Receptors and Retinoic Acid Signaling -- RXRs: Collegial Partners -- Nuclear and Extra-Nuclear Effects of Retinoic Acid Receptors: How they are interconnected- The Roles of Retinoic Acid and Retinoic Acid Receptors in Inducing Epigenetic Changes -- RARs and micro RNAs -- Integrative genomics to dissect retinoids functions -- Complexity of the RAR‐Mediated Transcriptional Regulatory Programs -- Index.
Record Nr. UNINA-9910298344403321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Materiale a stampa
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