Dissecting Regulatory Interactions of RNA and Protein [[electronic resource] ] : Combining Computation and High-throughput Experiments in Systems Biology / / by Marvin Jens |
Autore | Jens Marvin |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (115 p.) |
Disciplina | 574.873282 |
Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
Soggetto topico |
Computational intelligence
Systems biology Biological systems Gene expression Biochemistry Computational Intelligence Systems Biology Gene Expression Biochemistry, general |
ISBN | 3-319-07082-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Computational analysis of PAR-CLIP data -- Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR -- Binding site occupancy with competition interactions in equilibrium -- Circular RNAs are a large class of animal RNAs with regulatory potency -- Discussion -- Methods. |
Record Nr. | UNINA-9910299748203321 |
Jens Marvin | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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DNA Cloning: A Hands-on Approach [[electronic resource] /] / by Seok-Yong Choi, Hyunju Ro, Hankuil Yi |
Autore | Choi Seok-Yong |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (139 pages) |
Disciplina | 574.873282 |
Soggetto topico |
Gene expression
Genetic engineering Plant genetics Animal genetics Gene Expression Genetic Engineering Plant Genetics and Genomics Animal Genetics and Genomics |
ISBN | 94-024-1662-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I. What is cloning? -- Chapter 1.1 Definition of cloning -- Chapter 1.2 Discovering a new gene -- Chapter 1.3 Cloning in the past -- Chapter 1.4 Cloning in the present -- Part II. A prerequisite for cloning -- Chapter 2.1 Software useful for cloning design -- Chapter 2.2 Vector, plasmid, construct and the Kozak consensus sequence -- Chapter 2.3 Multiple cloning sites (MCS) -- Chapter 2.4 Restriction endonucleases and star activity -- Chapter 2.5 Agarose gel electrophoresis -- Chapter 2.6 Pouring LB agar plates -- Chapter 2.7 Competent cells -- Chapter 2.8 The conversion of DNA mass into molar concentration -- Chapter 2.9 Upon receiving new plasmids -- Chapter 2.10 cDNA library -- Part III. The first step in cloning -- Chapter 3.1 Cut & paste -- Chapter 3.2 DNA sequencing and direct sequencing -- Chapter 3.3 PCR and nested PCR -- Chapter 3.4 Fill-in (Full & Partial) -- Chapter 3.5 Compatible cohesive ends -- Chapter 3.6 Methylation -- Chapter 3.7 Three-piece ligation -- Chapter 3.8 Site-directed mutagenesis -- Chapter 3.9 Structure of plant transformation vectors -- Chapter 3.10 Transformation of R. radiobacter -- Part IV. The next step of cloning -- Chapter 4.1 How to insert a DNA fragment into a gene -- Chapter 4.2 How to delete an internal region of a gene -- Chapter 4.3 How to insert an epitope tag into a gene -- Chapter 4.4 Translational fusion vs. transcriptional fusion -- Part V. The last steps of cloning -- Chapter 5.1 Method for cloning similar genes in different species -- Chapter 5.2 RACE (rapid amplification of cDNA ends) -- Chapter 5.3 BAC recombineering -- Chapter 5.4 Old trick: partial digestion -- Chapter 5.5 Modification of a vector -- Chapter 5.6 When you notice a frame shift mutation upon cloning -- Chapter 5.7 Reality of cloning: an extremely unlucky case -- Part VI. Methods that make your cloning life easier -- Chapter 6.1 TA cloning and production of a T-vector -- Chapter 6.2 TOPO TA cloning -- Chapter 6.3 Gateway cloning -- Chapter 6.4 Golden Gate Assembly for a modular cloning -- Chapter 6.5 In-Fusion Sequence and Ligation-Independent Cloning (In-Fusion SLIC) -- Chapter 6.6 T4 DNA Polymerase Sequence-and Ligation-Independent Cloning (T4 DNA Pol SLIC) -- Chapter 6.7 Non-template PCR cloning -- Part VII. Advice to cloners -- Chapter 7.1 When cloning is not going well -- Chapter 7.2 Keep your cloning data organized -- Appendix 1. Further readings -- Appendix 2. Abbreviations -- Appendix 3. Index. |
Record Nr. | UNINA-9910337954003321 |
Choi Seok-Yong | ||
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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DNA Methyltransferases - Role and Function [[electronic resource] /] / edited by Albert Jeltsch, Renata Z. Jurkowska |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (VIII, 535 p. 61 illus., 57 illus. in color.) |
Disciplina | 572.86 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Cell biology
Gene expression Cytogenetics Cell Biology Gene Expression |
ISBN | 3-319-43624-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Mechanisms and biological roles of DNA methylation and DNA methyltransferases – from past achievements to future challenges -- DNA and RNA pyrimidine nucleobase alkylation at the carbon-5 position -- Bacterial DNA methylation and methylomes -- Domain structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA methyltransferases -- Enzymology of mammalian DNA methyltransferases -- Genetic studies on mammalian DNA methyltransferases -- The role of DNA methylation in cancer -- Structure and mechanism of plant DNA methyltransferases -- DNA methylation and gene regulation in honey bees: from genome-wide analyses to obligatory epi-alleles -- N6-methyladenine: a conserved and dynamic DNA mark -- Pathways of DNA demethylation -- Structure and function of TET enzymes -- Proteins that read DNA methylation -- DNA base flipping – a general mechanism for writing, reading, and erasing DNA modifications -- Current and emerging technologies for the analysis of the genome-wide and locus-specific DNA methylation patterns -- DNA methyltransferase inhibitors – development and applications -- Rewriting DNA methylation signatures at will: the curable genome within reach? -- Engineering and directed evolution of DNA methyltransferases -- DNA labeling using DNA methyltransferases. |
Record Nr. | UNINA-9910150454903321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]] |
Autore | Baldi Pierre |
Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2002 |
Descrizione fisica | 1 online resource (xvi, 213 pages) : digital, PDF file(s) |
Disciplina | 572.8/65 |
Soggetto topico |
DNA microarrays
Gene expression |
ISBN |
1-107-13017-4
1-280-16041-1 9786610160419 0-511-06321-0 0-511-11922-4 1-139-14694-7 0-511-05688-5 0-511-32267-4 0-511-54177-5 0-511-07167-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction,clustering,and regulatory regions; 7 The design, analysis,and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index |
Altri titoli varianti | DNA Microarrays & Gene Expression |
Record Nr. | UNINA-9910450497003321 |
Baldi Pierre | ||
Cambridge : , : Cambridge University Press, , 2002 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]] |
Autore | Baldi Pierre |
Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2002 |
Descrizione fisica | 1 online resource (xvi, 213 pages) : digital, PDF file(s) |
Disciplina | 572.8/65 |
Soggetto topico |
DNA microarrays
Gene expression |
ISBN |
1-107-13017-4
1-280-16041-1 9786610160419 0-511-06321-0 0-511-11922-4 1-139-14694-7 0-511-05688-5 0-511-32267-4 0-511-54177-5 0-511-07167-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction,clustering,and regulatory regions; 7 The design, analysis,and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index |
Altri titoli varianti | DNA Microarrays & Gene Expression |
Record Nr. | UNINA-9910783118803321 |
Baldi Pierre | ||
Cambridge : , : Cambridge University Press, , 2002 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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DNA microarrays and gene expression / / Pierre Baldi and G. Wesley Hatfield [[electronic resource]] |
Autore | Baldi Pierre |
Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , 2002 |
Descrizione fisica | 1 online resource (xvi, 213 pages) : digital, PDF file(s) |
Disciplina | 572.8/65 |
Soggetto topico |
DNA microarrays
Gene expression |
ISBN |
1-107-13017-4
1-280-16041-1 9786610160419 0-511-06321-0 0-511-11922-4 1-139-14694-7 0-511-05688-5 0-511-32267-4 0-511-54177-5 0-511-07167-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction,clustering,and regulatory regions; 7 The design, analysis,and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index |
Altri titoli varianti | DNA Microarrays & Gene Expression |
Record Nr. | UNINA-9910829175403321 |
Baldi Pierre | ||
Cambridge : , : Cambridge University Press, , 2002 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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DNA modifications in the brain : neuroepigenetic regulation of gene expression / / Timothy Bredy |
Autore | Bredy Timothy |
Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2017 |
Descrizione fisica | 1 online resource (182 pages) : illustrations, tables |
Disciplina | 574.87322 |
Soggetto topico | Gene expression |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- History and modern view on DNA modifications in the brain / B.F. Vanyushin and V.V. Ashapkin -- Approaches to detecting DNA base modification in the brain / X. Li and W. Wei -- Active DNA demethylation in neurodevelopment / Y. Kang, Z. Wang and P. Jin -- TET and 5hmC in neurodevelopment and the adult brain / M. Fasolino, S.A. Welsh and Z. Zhou -- Beyond mCG : DNA methylation in noncanonical sequence context / E.A. Mukamel and R. Lister -- DNA modifications and memory / J.J. Day -- Measuring CpG methylation by SMRT sequencing / Y. Suzuki, J. Korlach and S. Morishita -- Epigenetic modifications of DNA and drug addiction / J. Feng and E.J. Nestler -- What does the future hold for the study of nucleic acid modifications in the brain? / P.R. Marshall and T.W. Bredy. |
Record Nr. | UNINA-9910583314503321 |
Bredy Timothy | ||
Amsterdam, [Netherlands] : , : Academic Press, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Early Life Origins of Ageing and Longevity [[electronic resource] /] / edited by Alexander Vaiserman |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (313 pages) : illustrations |
Disciplina | 612.67 |
Collana | Healthy Ageing and Longevity |
Soggetto topico |
Aging
Developmental biology Gene expression Geriatrics Biogerontology Developmental Biology Gene Expression Geriatrics/Gerontology |
ISBN | 3-030-24958-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | SECTION I OVERVIEW -- Introductory chapter -- SECTION II EXPERIMENTAL STUDY OF DOHAD -- Early Life Programming of Aging in Genetically Long-Lived Mice -- Immunological Basis of In Utero Programming of Adult Disease -- Developmental Programming of the GH/IGF Axis and Long Term Health -- Programming of Stress Responses -- Early-life Nutritional Programming of Adult Health Status -- Effects of In-Utero Conditions on Adult Feeding Preferences -- IUGR-Related Programming of Metabolic Syndrome and Type 2 Diabetes -- Early-life Programming of Osteoporosis -- Developmental Epigenetic Programming of Skeletal Muscle Aging -- Effect of fetal and child health on kidney development and long-term risk of hypertension and kidney disease. -- Developmental Programming of Neuroimmune Function -- Epigenetics and neurodegeneration: role of early-life nutrition -- SECTION III EPIDEMIOLOGICAL EVIDENCE -- Prenatal Undernutrition and Ageing and Longevity -- Influence of Maternal Obesity on the Long-Term Health of Offspring -- Early Life Predictors of Women's Health and Ageing -- Early-Life Predictors of Exceptional Longevity -- Prenatal Undernutrition and Effects on Physical and Mental Health -- Ancestral and early origins of adult mortality - a multigenerational approach -- SECTION IV PERSPECTIVES AND IMPLICATIONS -- Social Policy and Public Health Perspectives of DOHaD: Implications for Policy Advocacy, Cross-Sectorial Collaboration and Health Promotion -- Index. |
Record Nr. | UNINA-9910349451603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Endometrial gene expression : an emerging paradigm for reproductive disorders / / Editor, Joanne Kwak-Kim |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2020] |
Descrizione fisica | 1 online resource (XIII, 220 p. 15 illus. in color.) |
Disciplina | 618.1 |
Soggetto topico |
Gynecology
Gene expression Reproductive health |
ISBN | 3-030-28584-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Endometrial Development and Its Fine Structure -- Molecular Biology Techniques for Endometrial Gene Expression: Recent Technological Advances -- T Cell-related Endometrial Gene Expression Abnormalities -- Role of Immunoregulatory Cytokine IL-15 in the Endometrium -- Endometrial Gene Expression in Women with Repeated Implantation Failure -- Endometrial Receptivity by ERA for Infertility -- Endometrium Gene Expression and Epigenetic Regulation in Reproductive Failure -- Endometrial Gene Expression for HHV6 -- Infection and Endometrial Gene Expression: HHV6 and Infertility -- Endometrial Immune Inflammatory Gene Signature in Endometriosis -- Gene Expression in Endometriosis -- MicroRNA and Endometriosis -- Metabolic and Nutritional Impact on Endometrial Gene Expression and Reproductive Disorders. |
Record Nr. | UNINA-9910369931503321 |
Cham, Switzerland : , : Springer, , [2020] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Epigenesis, Genetic [[electronic resource] /] / edited by Elisabetta Baldi, Monica Muratori |
Edizione | [2nd ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (216 pages) |
Disciplina | 573.21 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Gene expression
Medical genetics Human physiology Gene Expression Gene Function Human Physiology |
ISBN | 3-030-21664-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Genetic factors affecting sperm chromatin structure -- Mechanisms of origin of chromosome deletions and rearrangements in spermatozoa -- The sperm epigenome: implications for ART outcomes -- Epigenetic transgenerational inheritance -- Environmental genetic and epigenetic sperm alterations -- Sperm DNA fragmentation: mechanisms of origin -- Sperm DNA fragmentation: consequences for reproduction -- Oxidative damage to sperm DNA: attack and defence -- Interventions to prevent sperm DNA damage effects on reproduction.-Cryopreservation of sperm: effects on chromatin and strategies to prevent them -- Effect on sperm DNA quality following sperm selection for ART: new insights -- Sperm DNA damage in cancer patients -- Index. |
Record Nr. | UNINA-9910349454403321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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