Regulation of Cytokine Gene Expression in Immunity and Diseases [[electronic resource] /] / edited by Xiaojing Ma |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (228 p.) |
Disciplina | 610 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Immunology
Gene expression Cytokines Growth factors Cell biology Gene Expression Cytokines and Growth Factors Cell Biology |
ISBN | 9789402409215 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Regulation of IFN-γ expression -- Regulation of The interleukin-1 family -- Regulation of IL-4 Expression in Immunity and Diseases -- Regulation of IL-6 in immunity and diseases -- Regulation of Interleukin-10 Expression -- Regulation of Interleukin-12 Production in Antigen-Presenting Cells -- Regulation of Interleukin-17 production -- Regulation of interleukin-23 expression in health and disease -- Regulation and immune function of IL-27 -- The immunobiology of Interleukin-35 and its regulation and gene expression. |
Record Nr. | UNINA-9910136605203321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Regulatory Nascent Polypeptides [[electronic resource] /] / edited by Koreaki Ito |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (313 p.) |
Disciplina |
547.75
572.65 |
Soggetto topico |
Biochemistry
Cell biology Human genetics Gene expression Biochemistry, general Cell Biology Human Genetics Gene Expression |
ISBN | 4-431-55052-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Preface; Contents; Part I: Introduction; Chapter 1: Biological Significance of Nascent Polypeptides That Stall the Ribosome; 1.1 Overview; 1.1.1 Importance of Nascent Peptidyl-tRNA in the ``Translation Concert ́ ́; 1.1.2 Nascent Polypeptides Can Modulate Progression of Their Own Translation; 1.1.3 Nascent Polypeptide-Mediated Translation Modulation Responds to Environmental Changes; 1.1.4 Regulatory Nascent Polypeptides Monitor and Control Cellular Physiology; 1.2 Concepts Characteristically Associated with Regulatory Nascent Polypeptides
1.2.1 The Exit Tunnel Is Not Necessarily ``Teflon Like ́ ́1.2.2 Ribosomes Cannot Readily Synthesize Proteins Representing All the Possible Amino Acid Sequences; 1.2.3 The Use of a Posttranslational Determinant to Control Ongoing Translation; 1.2.4 Proteins Can Function Before They Are Completely Formed; 1.2.5 Nascent Polypeptides Can Direct the Subcellular Localization of mRNA; 1.2.6 Arrest Sequences Are Divergent in Their Primary Sequences; 1.2.7 Is Polypeptide-Directed Translational Pausing Ubiquitous?; 1.2.8 Arrest Control by the Dynamic Behavior of the Nascent Chain 1.2.9 Quality Control Systems and Regulatory Nascent PolypeptidesReferences; Part II: The Ribosome and the Exit Tunnel; Chapter 2: Recent Progress in Ribosome Structure Studies; 2.1 Introduction; 2.2 Structure of the Ribosome; 2.3 Mechanism of Translation; 2.3.1 Initiation of Translation; 2.3.2 The Elongation Cycle; 2.3.3 Mechanism of Decoding: Preliminary Binding; 2.3.4 Mechanism of Decoding: Proofreading; 2.3.5 The Peptide Bond Formation; 2.3.6 Translocation; 2.3.7 Termination and Recycling; 2.3.8 Polypeptide Exit Tunnel; References Chapter 3: Structures of Nascent Polypeptide Chain-Dependent-Stalled Ribosome Complexes3.1 Introduction; 3.2 Cryo-EM Structure of the TnaC-SRC; 3.3 Cryo-EM Structure of the SecM-SRC; 3.4 Cryo-EM Structure of the CMV-SRC; 3.5 Cryo-EM Structure of the AAP-SRC; 3.6 Conclusions; References; Chapter 4: Tunnel Vision: Insights from Biochemical and Biophysical Studies; 4.1 Introduction; 4.2 The Physicochemical Properties of the Tunnel; 4.2.1 Tunnel Geometry; 4.2.2 Electrostatic Potentials in the Tunnel; 4.2.3 Effective Debye Length Along the Tunnel; 4.2.4 Water in the Tunnel; 4.2.5 pH in the Tunnel 4.2.6 Solvent-Accessible Volume4.3 The Peptide in the Tunnel; 4.3.1 Side-Chain Chemistry: A Couple of Questions; 4.3.2 Peptide Folding in the Tunnel; 4.3.2.1 Compaction in the Tunnel; 4.3.2.2 Tertiary Folding in the Tunnel; 4.3.2.3 A Folding Vestibule in the Tunnel; 4.3.3 Peptide Movement Along the Tunnel; 4.3.4 Rearrangements in the Tunnel: Regional Discrimination and Pathway; 4.4 Movement of Tunnel Wall Components; 4.5 Peptide-Tunnel Interactions: Relay Mechanisms; 4.6 A New View Going Forward; References Chapter 5: Nascent Peptide-Induced Signaling from the Exit Tunnel to the Outside of the Ribosome |
Record Nr. | UNINA-9910298351103321 |
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders [[electronic resource] /] / edited by Paul C. Guest |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (XIII, 328 p. 28 illus., 26 illus. in color.) |
Disciplina | 570 |
Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
Soggetto topico |
Systems biology
Proteomics Gene expression Systems Biology Gene Expression |
ISBN | 3-030-05542-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. The Potential of ‘Omics to Link Lipid Metabolism and Genetic and Comorbidity Risk Factors of Alzheimer’s Disease in African Americans -- 2. The Role of Biomarkers in Alzheimer’s Disease Drug Development -- 3. Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- 4. Lymphocytes, Platelets, Erythrocytes and Exosomes as Possible Biomarkers for Alzheimer's Disease Clinical Diagnosis -- 5. Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms -- 6. Neuroimaging Studies of Cognitive Function in Schizophrenia -- 7. The Role of Biomarkers in Psychiatry -- 8. Interactome Studies of Psychiatric Disorders -- 9. MicroRNAs in Major Depressive Disorder -- 10. Proteomic Markers for Depression -- 11. Advances in Biomarker Studies in Autism Spectrum Disorders -- 12. Proteomic Investigations of Autism Spectrum Disorder: Past Findings, Current Challenges and Future Prospects -- 13. Role of the Gut Microbiome in Autism Spectrum Disorders -- 14. Metabolomic Biomarkers in Mental Disorders: Bipolar Disorder and Schizophrenia -- 15. Early Detection and Treatment of Patients with Alzheimer’s Disease: Future Perspectives. |
Record Nr. | UNINA-9910337938103321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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RNA Activation [[electronic resource] /] / edited by Long-Cheng Li |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XIV, 239 p. 45 illus., 38 illus. in color.) |
Disciplina | 572.88 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Gene expression
Biochemistry Cell biology Molecular biology Cancer research Gene Expression Biochemistry, general Cell Biology Molecular Medicine Cancer Research |
ISBN | 981-10-4310-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | PART I Exogenous RNAa -- PART II Endogenous RNAa -- PART III RNA activation guided by other small RNAs -- PART IV Developing RNAa-based therapeutics -- . |
Record Nr. | UNINA-9910253908003321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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RNA Metabolism in Mitochondria [[electronic resource] /] / edited by Jorge Cruz-Reyes, Michael W. Gray |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (IX, 249 p. 39 illus., 37 illus. in color.) |
Disciplina | 572.84 |
Collana | Nucleic Acids and Molecular Biology |
Soggetto topico |
Nucleic acids
Gene expression Microbiology Nucleic Acid Chemistry Gene Expression Eukaryotic Microbiology |
ISBN | 3-319-78190-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | The mitochondrial transcription machinery -- Mitochondrial RNA turnover in Metazoa -- Mitochondrial RNase P complex in animals: mitochondrial tRNA processing and links to disease -- Intercompartment RNA trafficking in mitochondrial function and communication -- Control mechanisms of the holo-editosome in trypanosomes -- Mitochondrial RNA editing and processing in diplonemid protists -- Mechanisms and evolution of tRNA 5′-editing in mitochondria -- Editing of mitochondrial RNAs in Physarum polycephalum -- Requirement of various protein combinations for each C-to-U RNA editosome in plant organelles. . |
Record Nr. | UNINA-9910298428903321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Role of Capsaicin in Oxidative Stress and Cancer [[electronic resource] /] / edited by Sanjay K. Srivastava |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (178 p.) |
Disciplina | 616.994061 |
Collana | Diet and Cancer |
Soggetto topico |
Cancer research
Apoptosis Pharmacology Gene expression Cell biology Cancer Research Science, Humanities and Social Sciences, multidisciplinary Pharmacology/Toxicology Gene Expression Cell Biology |
ISBN | 94-007-6317-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910741200303321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The role of microRNAs in controlling protein expression noise / / von Diplom Biophysiker Jörn Matthias Schmiedel |
Autore | Schmiedel Jörn Matthias <1985-> |
Pubbl/distr/stampa | Berlin : , : Logos Verlag Berlin, , [2016] |
Descrizione fisica | 1 online resource (116 pages) : illustrations |
Disciplina | 572.865 |
Soggetto topico |
Gene expression
MicroRNA |
Soggetto genere / forma | Electronic books. |
ISBN | 3-8325-8802-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910467241203321 |
Schmiedel Jörn Matthias <1985-> | ||
Berlin : , : Logos Verlag Berlin, , [2016] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The role of microRNAs in controlling protein expression noise / / von Diplom Biophysiker Jörn Matthias Schmiedel |
Autore | Schmiedel Jörn Matthias <1985-> |
Pubbl/distr/stampa | Berlin : , : Logos Verlag Berlin, , [2016] |
Descrizione fisica | 1 online resource (116 pages) : illustrations |
Disciplina | 572.865 |
Soggetto topico |
Gene expression
MicroRNA |
ISBN | 3-8325-8802-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910793929103321 |
Schmiedel Jörn Matthias <1985-> | ||
Berlin : , : Logos Verlag Berlin, , [2016] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The role of microRNAs in controlling protein expression noise / / von Diplom Biophysiker Jörn Matthias Schmiedel |
Autore | Schmiedel Jörn Matthias <1985-> |
Pubbl/distr/stampa | Berlin : , : Logos Verlag Berlin, , [2016] |
Descrizione fisica | 1 online resource (116 pages) : illustrations |
Disciplina | 572.865 |
Soggetto topico |
Gene expression
MicroRNA |
ISBN | 3-8325-8802-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910809059703321 |
Schmiedel Jörn Matthias <1985-> | ||
Berlin : , : Logos Verlag Berlin, , [2016] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Role of Transcription Factors in Gastrointestinal Malignancies [[electronic resource] /] / edited by Ganji Purnachandra Nagaraju, Pallaval Veera Bramhachari |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (501 pages) |
Disciplina | 616.9943307 |
Soggetto topico |
Cancer research
Gene expression Cytokines Growth factors Oncology Cancer Research Gene Expression Cytokines and Growth Factors Oncology |
ISBN | 981-10-6728-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1.Overview of Transcription factors in gastrointestinal malignancies -- Chapter 2. YY1 and KLF4: their role in gastrointestinal malignancies -- Chapter 3. AP1: its role in gastrointestinal malignancies -- Chapter 4. Overview of Transcription factors in Esophagus cancer -- Chapter 5. Interplay of transcription factors NF-kB/STAT3 and non-coding RNAs in oesophageal squamous cell carcinoma -- Chapter 6. Hypoxia-Inducible Factor-1 (HIF-1): perspective in esophageal cancer -- Chapter 7. SP1 and AP1: their role in esophageal malignancy -- Chapter 8. Role and Regulation of Transcriptional Factors in Gastric Cancer -- Chapter 9. Role of STAT3 in Gastric cancer initiation, development and progression -- Chapter 10. Colorectal cancer: recent advances in targeting transcription factors and micro RNA -- Chapter 11. NF-B: Its role in colorectal cancer -- Chapter 12. Hypoxia-inducible factors (HIFs) role in the maintenance of stemness and malignancy of colorectal cancer -- Chapter 13. Role of STAT3 in Colorectal Cancer Development -- Chapter 14. E2F1: A Transcriptional Machinery in Colon Cancer -- Chapter 15. Role of Notch signaling in colorectal cancer -- Chapter 16. NF-B: Its role in Pancreatic cancer -- Chapter 17. Role of STAT-3 in pancreatic cancer -- Chapter 18. Role of hypoxia inducible factor (HIF) in pancreatic cancer and its therapeutic Inhibitors -- Chapter 19. Role of E2F1 in pancreatic cancer -- Chapter 20. Role of Arachidonic Acid pathway and its associated transcriptional factors in Pancreatic Cancer -- Chapter 21. Role of NF-kB in liver carcinogenesis -- Chapter 22. Role of hypoxia inducible factor (HIF) in liver cancer -- Chapter 23. Role of SP1 transcription factor in liver cancer -- Chapter 24. Targeting transcription factors in GI cancers and future prospective (Summary). . |
Record Nr. | UNINA-9910279576303321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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