Systems Biology of Tumor Microenvironment [[electronic resource] ] : Quantitative Modeling and Simulations / / edited by Katarzyna A. Rejniak |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (264 p.) |
Disciplina | 610 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Cancer research
Biomathematics Biophysics Biological physics Cancer Research Mathematical and Computational Biology Biological and Medical Physics, Biophysics |
ISBN | 9783319420233 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Foreword -- Preface -- List of Contributors -- Image Analysis of the Tumor Microenvironment -- Hypoxia in Gliomas: Opening Therapeutical Opportunities Using a Mathematical-Based Approach -- Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen -- Cell-ECM Interactions in Tumor Invasion -- Circulating Tumor Cells: When Solid tumor Meets Fluid Microenvironment -- Modeling Proteolytically Driven Tumor Lymphangiogenesis -- Positive feedback loops between inflammatory, bone and cancer cells during metastatic niche construction -- Microenvironmental Niches and Sanctuaries: a Route to Acquired Resistance -- The Tumor Microenvironment as a Barrier to Cancer Nanotherapy -- Microenvironment-Mediated Modeling of Tumor Response to Vascular-Targeting Drugs -- Optimizing Chemotherapeutic Anti-Cancer Treatment and the Tumor Microenvironment: An Analysis of Mathematical Models -- Progress towards computational 3-D multicellular systems biology -- Index. |
Record Nr. | UNINA-9910136620803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Systems Pharmacology and Pharmacodynamics [[electronic resource] /] / edited by Donald E. Mager, Holly H.C. Kimko |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (XIII, 511 p. 113 illus., 57 illus. in color.) |
Disciplina | 615.1 |
Collana | AAPS Advances in the Pharmaceutical Sciences Series |
Soggetto topico |
Pharmaceutical technology
Biomathematics Medical biochemistry Pharmaceutical Sciences/Technology Mathematical and Computational Biology Medical Biochemistry |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Role of Systems Modeling in Regulatory Drug Approval -- Quantitative Systems Pharmacology: Applications and Adoption in Drug Development -- Systems Pharmacology: An Overview -- Discrete dynamic modeling: a network approach for systems pharmacology -- Kinetic Models of Biochemical Signaling Networks -- Mechanistic Models of Physiological Control Systems -- Foundations of Pharmacodynamic Systems Analysis -- Direct, Indirect, and Signal Transduction Response Modeling -- Irreversible Pharmacodynamics -- Feedback Control Indirect Response Models -- Nonlinear Mixed Effects Modeling in Systems Pharmacology -- Detecting Pharmacokinetic and Pharmacodynamic Covariates From High-Dimensional Data -- Multi-Scale Modeling of Drug Action in the Nervous System -- Mechanistic Modeling of Inflammation -- Systems Pharmacology of Tyrosine Kinase Inhibitor-Associated Toxicities -- Translational Modeling of Antibacterial Agents -- Viral Dynamic Modeling of Hepatitis C Virus Infection: Past Successes and Future Challenges -- Using Systems Pharmacology to Advance Oncology Drug Development -- Systems Pharmacology Modeling in Type 2 Diabetes Mellitus. |
Record Nr. | UNINA-9910155327803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations [[electronic resource] /] / edited by Vishwesh V. Kulkarni, Guy-Bart Stan, Karthik Raman |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (338 p.) |
Disciplina | 570.285 |
Soggetto topico |
Medicine
Bioinformatics Systems biology Biomathematics Pharmaceutical technology Applied mathematics Engineering mathematics Biomedicine, general Computational Biology/Bioinformatics Systems Biology Mathematical and Computational Biology Pharmaceutical Sciences/Technology Mathematical and Computational Engineering |
ISBN | 94-017-9041-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1 On the Mathematics of the Law of Mass Action -- 2 Structural Analysis of Biological Networks -- 3 Guaranteeing Spatial Uniformity in Reaction-Diffusion Systems Using Weighted L2-norm Contractions -- 4 Robust Tunable Transcriptional Oscillators using Dynamic Inversion -- 5 Towards the Modular Decomposition of the Metabolic Network -- 6 An Optimal Control Approach to Seizure Detection in Drug-Resistant Epilepsy -- 7 Model Reduction of Genetic-Metabolic Networks via Time-Scale Separation -- 8 Networks, Metrics, and Systems Biology -- 9 Understanding and Predicting Biological Networks Using Linear System Identification -- 10 Model Checking in Biology -- 11 Computational Design of Informative Experiments in Systems Biology -- 12 Predicting Phenotype from Genotype through Reconstruction and Integrative Modeling of Metabolic and Regulatory Networks -- Index. |
Record Nr. | UNINA-9910298348503321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems [[electronic resource] /] / edited by Vishwesh V. Kulkarni, Guy-Bart Stan, Karthik Raman |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (304 p.) |
Disciplina | 570.285 |
Soggetto topico |
Medicine
Applied mathematics Engineering mathematics Bioinformatics Systems biology Biomathematics Pharmaceutical technology Biomedicine, general Mathematical and Computational Engineering Computational Biology/Bioinformatics Systems Biology Mathematical and Computational Biology Pharmaceutical Sciences/Technology |
ISBN | 94-017-9047-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1 Network Biomarker Construction for Molecular Investigation and Diagnosis of Lung Cancervia Microarray Data -- 2 The Impact of Next Generation Sequencing Technology on Bacterial Genomics -- 3 Sensitivity Analysis of Circadian Entrainment in the Space of Phase Response Curves -- 4 Modelling and Analysis of Feedback Control Mechanisms Underlying Osmoregulation in Yeast -- 5 Analysis of Synchronizing Biochemical Networks via Incremental Dissipativity -- 6 Robustness Model Validation of Bistability in Biomolecular Systems -- 7 Meta-DNA: A DNA-Based Approach to Synthetic Biology -- 8 Towards Modeling Automation for Synthetic Biology -- 9 An Investigation of Signal Transduction and Irreversible Decision Making through Monostable and Bistable Switches -- 10 From Specification to Parameters: A Linearization Approach -- 11 Simplified Computational Design of Digital Synthetic Gene Circuits -- 12 Synthetic Biochemical Devices for Programmable Dynamic Behavior -- Index. |
Record Nr. | UNINA-9910298350503321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Targeted Cancer Treatment in Silico [[electronic resource] ] : Small Molecule Inhibitors and Oncolytic Viruses / / by Natalia L. Komarova, Dominik Wodarz |
Autore | Komarova Natalia L |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Birkhäuser, , 2014 |
Descrizione fisica | 1 online resource (XV, 227 p. 71 illus., 26 illus. in color.) : online resource |
Disciplina | 616.99406 |
Collana | Modeling and Simulation in Science, Engineering and Technology |
Soggetto topico |
Biomathematics
Cancer research Oncology Applied mathematics Engineering mathematics Physiological, Cellular and Medical Topics Cancer Research Mathematical and Computational Biology Oncology Genetics and Population Dynamics Applications of Mathematics |
ISBN | 1-4614-8301-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Background and Scope of the Book -- Part I Treatment of Cancer with Small Molecule Inhibitors -- An Introduction to Small Molecule Inhibitors and Chronic Myeloid Leukemia -- Basic Dynamics of Chronic Myeloid Leukemia During Imatinib Treatment -- Stochastic Modeling of Cellular Growth, Treatment, and Resistance Generation -- Evolutionary Dynamics of Drug Resistant Mutants in Targeted Treatment of CML -- Effect of Cellular Quiescence on the Evolution of Drug Resistance in CML -- Combination Therapies: Short term versus Long term Strategies -- Cross Resistance: Treatment and Modeling -- Mathematical Modeling of Cyclic Cancer Treatments -- Part II Treatment of Cancer with Oncolytic Viruses -- Introduction to Oncolytic Viruses -- Basic Dynamics of Oncolytic Viruses -- Mitotic Virus Transmission and Immune Responses -- Axiomatic Approaches to Oncolytic Virus Modeling -- Spatial Oncolytic Virus Dynamics -- Oncolytic Viruses and the Eradication of Drug-resistant Tumor Cells. |
Record Nr. | UNINA-9910299975303321 |
Komarova Natalia L | ||
New York, NY : , : Springer New York : , : Imprint : Birkhäuser, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Temporal network epidemiology / / Naoki Masuda, Petter Holme, editors |
Pubbl/distr/stampa | Singapore : , : Springer, , [2017] |
Descrizione fisica | 1 online resource (vi, 342 pages) : 121 illustrations, 83 illustrations in color |
Disciplina | 570.285 |
Collana | Theoretical biology |
Soggetto topico |
Biomathematics
Bioinformatics Computational biology Epidemiology Medical microbiology Systems biology Biological systems |
ISBN | 981-10-5287-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910254288403321 |
Singapore : , : Springer, , [2017] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Theoretical Molecular Biophysics [[electronic resource] /] / by Philipp O.J. Scherer, Sighart F. Fischer |
Autore | Scherer Philipp O.J |
Edizione | [2nd ed. 2017.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XVI, 513 p. 226 illus., 27 illus. in color.) |
Disciplina | 572.8 |
Collana | Biological and Medical Physics, Biomedical Engineering |
Soggetto topico |
Biophysics
Biological physics Biomathematics Biomedical engineering Proteins Biochemical engineering Biological and Medical Physics, Biophysics Mathematical and Computational Biology Biomedical Engineering and Bioengineering Protein Science Biochemical Engineering |
ISBN | 3-662-55671-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Statistical Mechanics of Biopolymers -- Protein Electrostatics and Solvation -- Reaction Kinetics -- Transport Processes -- Reaction Rate Theory -- Elementary Photophysics -- Elementary Photoinduced Processes -- Molecular Motor Models. |
Record Nr. | UNINA-9910254586403321 |
Scherer Philipp O.J | ||
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Theory and Applications of Difference Equations and Discrete Dynamical Systems [[electronic resource] ] : ICDEA, Muscat, Oman, May 26 - 30, 2013 / / edited by Ziyad AlSharawi, Jim M. Cushing, Saber Elaydi |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (229 p.) |
Disciplina | 512.94 |
Collana | Springer Proceedings in Mathematics & Statistics |
Soggetto topico |
Difference equations
Functional equations Dynamics Ergodic theory Biomathematics Applied mathematics Engineering mathematics Mathematical models Difference and Functional Equations Dynamical Systems and Ergodic Theory Genetics and Population Dynamics Applications of Mathematics Mathematical Modeling and Industrial Mathematics |
ISBN | 3-662-44140-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Papers by Invited Speakers: Competitive exclusion through discrete time models: Azmy S. Ackleh and Paul L. Salceanu -- Benford solutions of linear difference equations: Arno Berger and Gideon Eshun -- Harvesting and dynamics in some one-dimensional population models: Eduardo Liz and Frank M. Hilker -- Chaos and wild chaos in Lorenz-type systems: Hinke M. Osinga, Bernd Krauskopf and Stefanie Hittmeyer -- Contributed Papers: Almost automorphic sequences and their application to a model of cellular neural network: Syed Abbas -- Advances in periodic difference equations with open problems: Ziyad AlSharawi, Jose S. Canovas and Antonio Linero -- An Evolutionary Beverton-Holt Model: J. M. Cushing -- The periodic decomposition problem: Balint Farkas and Szilard Gy. Revesz -- Existence of periodic and almost periodic solutions of discrete Ricker delay models: Yoshihiro Hamaya -- Generalized Lagrange identity for discrete symplectic systems and applications in Weyl-Titchmarsh Theory: Roman Simon Hilscher and Petr Zemanek -- Dynamic selection systems and replicator equations: Zdenek Pospsil -- Asymptotic equivalence of difference equations in Banach Space: Andrejs Reinfelds. |
Record Nr. | UNINA-9910299968703321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems [[electronic resource] /] / by Marc Thiriet |
Autore | Thiriet Marc |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (975 p.) |
Disciplina | 612.1 |
Collana | Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems |
Soggetto topico |
Biophysics
Biological physics Biomedical engineering Biomathematics Systems biology Fluid mechanics Cardiology Biological and Medical Physics, Biophysics Biomedical Engineering and Bioengineering Mathematical and Computational Biology Systems Biology Engineering Fluid Dynamics |
ISBN |
1-299-19734-5
1-4614-5966-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- Chapter 1: Blood -- Chapter 2: Hematopoiesis -- Chapter 3: Blood Cells -- Chapter 4: Lymph Drainage -- Chapter 5: Cardiomyocytes -- Chapter 6: Heart Wall -- Chapter 7: Vessel Wall -- Chapter 8: Smooth Myocytes -- Chapter 9: Vascular Endothelium -- Chapter 10: Vascular Growth -- Chapter 11: Tissue Development, Repair, and Remodeling -- Chapter 12: Airway Surface Liquid and Respiratory Mucus -- Chapter 13: Surfactant -- Chapter 14: Conclusion -- References -- List of Currently Used Prefixes and Suffixes -- List of Aliases -- Complementary Lists of Notations -- Index. |
Record Nr. | UNINA-9910437983103321 |
Thiriet Marc | ||
New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Topics in Mathematical Biology [[electronic resource] /] / by Karl Peter Hadeler |
Autore | Hadeler Karl Peter |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XIV, 353 p. 28 illus., 2 illus. in color.) |
Disciplina | 570.151 |
Collana | Lecture Notes on Mathematical Modelling in the Life Sciences |
Soggetto topico |
Biomathematics
Mathematical and Computational Biology |
ISBN | 3-319-65621-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- 1.Coupling and quiescence -- 2.Delay and age -- 3.Lotka-Volterra and replicator systems -- 4.Ecology -- 5.Homogeneous systems -- 6.Epidemic models -- 7.Coupled movements -- 8.Traveling fronts -- Index. |
Record Nr. | UNINA-9910254297503321 |
Hadeler Karl Peter | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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