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Systems Biology of Tumor Microenvironment [[electronic resource] ] : Quantitative Modeling and Simulations / / edited by Katarzyna A. Rejniak
Systems Biology of Tumor Microenvironment [[electronic resource] ] : Quantitative Modeling and Simulations / / edited by Katarzyna A. Rejniak
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (264 p.)
Disciplina 610
Collana Advances in Experimental Medicine and Biology
Soggetto topico Cancer research
Biomathematics
Biophysics
Biological physics
Cancer Research
Mathematical and Computational Biology
Biological and Medical Physics, Biophysics
ISBN 9783319420233
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Foreword -- Preface -- List of Contributors -- Image Analysis of the Tumor Microenvironment -- Hypoxia in Gliomas: Opening Therapeutical Opportunities Using a Mathematical-Based Approach -- Computer Simulations of the Tumor Vasculature: Applications to Interstitial Fluid Flow, Drug Delivery, and Oxygen -- Cell-ECM Interactions in Tumor Invasion -- Circulating Tumor Cells: When Solid tumor Meets Fluid Microenvironment -- Modeling Proteolytically Driven Tumor Lymphangiogenesis -- Positive feedback loops between inflammatory, bone and cancer cells during metastatic niche construction -- Microenvironmental Niches and Sanctuaries: a Route to Acquired Resistance -- The Tumor Microenvironment as a Barrier to Cancer Nanotherapy -- Microenvironment-Mediated Modeling of Tumor Response to Vascular-Targeting Drugs -- Optimizing Chemotherapeutic Anti-Cancer Treatment and the Tumor Microenvironment: An Analysis of Mathematical Models -- Progress towards computational 3-D multicellular systems biology -- Index.
Record Nr. UNINA-9910136620803321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Systems Pharmacology and Pharmacodynamics [[electronic resource] /] / edited by Donald E. Mager, Holly H.C. Kimko
Systems Pharmacology and Pharmacodynamics [[electronic resource] /] / edited by Donald E. Mager, Holly H.C. Kimko
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (XIII, 511 p. 113 illus., 57 illus. in color.)
Disciplina 615.1
Collana AAPS Advances in the Pharmaceutical Sciences Series
Soggetto topico Pharmaceutical technology
Biomathematics
Medical biochemistry
Pharmaceutical Sciences/Technology
Mathematical and Computational Biology
Medical Biochemistry
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Role of Systems Modeling in Regulatory Drug Approval -- Quantitative Systems Pharmacology: Applications and Adoption in Drug Development -- Systems Pharmacology: An Overview -- Discrete dynamic modeling: a network approach for systems pharmacology -- Kinetic Models of Biochemical Signaling Networks -- Mechanistic Models of Physiological Control Systems -- Foundations of Pharmacodynamic Systems Analysis -- Direct, Indirect, and Signal Transduction Response Modeling -- Irreversible Pharmacodynamics -- Feedback Control Indirect Response Models -- Nonlinear Mixed Effects Modeling in Systems Pharmacology -- Detecting Pharmacokinetic and Pharmacodynamic Covariates From High-Dimensional Data -- Multi-Scale Modeling of Drug Action in the Nervous System -- Mechanistic Modeling of Inflammation -- Systems Pharmacology of Tyrosine Kinase Inhibitor-Associated Toxicities -- Translational Modeling of Antibacterial Agents -- Viral Dynamic Modeling of Hepatitis C Virus Infection: Past Successes and Future Challenges -- Using Systems Pharmacology to Advance Oncology Drug Development -- Systems Pharmacology Modeling in Type 2 Diabetes Mellitus.
Record Nr. UNINA-9910155327803321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations [[electronic resource] /] / edited by Vishwesh V. Kulkarni, Guy-Bart Stan, Karthik Raman
A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations [[electronic resource] /] / edited by Vishwesh V. Kulkarni, Guy-Bart Stan, Karthik Raman
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (338 p.)
Disciplina 570.285
Soggetto topico Medicine
Bioinformatics
Systems biology
Biomathematics
Pharmaceutical technology
Applied mathematics
Engineering mathematics
Biomedicine, general
Computational Biology/Bioinformatics
Systems Biology
Mathematical and Computational Biology
Pharmaceutical Sciences/Technology
Mathematical and Computational Engineering
ISBN 94-017-9041-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1 On the Mathematics of the Law of Mass Action -- 2 Structural Analysis of Biological Networks -- 3 Guaranteeing Spatial Uniformity in Reaction-Diffusion Systems Using Weighted L2-norm Contractions -- 4 Robust Tunable Transcriptional Oscillators using Dynamic Inversion -- 5 Towards the Modular Decomposition of the Metabolic Network -- 6 An Optimal Control Approach to Seizure Detection in Drug-Resistant Epilepsy -- 7 Model Reduction of Genetic-Metabolic Networks via Time-Scale Separation -- 8 Networks, Metrics, and Systems Biology -- 9 Understanding and Predicting Biological Networks Using Linear System Identification -- 10 Model Checking in Biology -- 11 Computational Design of Informative Experiments in Systems Biology -- 12 Predicting Phenotype from Genotype through Reconstruction and Integrative Modeling of Metabolic and Regulatory Networks -- Index.
Record Nr. UNINA-9910298348503321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems [[electronic resource] /] / edited by Vishwesh V. Kulkarni, Guy-Bart Stan, Karthik Raman
A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems [[electronic resource] /] / edited by Vishwesh V. Kulkarni, Guy-Bart Stan, Karthik Raman
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (304 p.)
Disciplina 570.285
Soggetto topico Medicine
Applied mathematics
Engineering mathematics
Bioinformatics
Systems biology
Biomathematics
Pharmaceutical technology
Biomedicine, general
Mathematical and Computational Engineering
Computational Biology/Bioinformatics
Systems Biology
Mathematical and Computational Biology
Pharmaceutical Sciences/Technology
ISBN 94-017-9047-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1 Network Biomarker Construction for Molecular Investigation and Diagnosis of Lung Cancervia Microarray Data -- 2 The Impact of Next Generation Sequencing Technology on Bacterial Genomics -- 3 Sensitivity Analysis of Circadian Entrainment in the Space of Phase Response Curves -- 4 Modelling and Analysis of Feedback Control Mechanisms Underlying Osmoregulation in Yeast -- 5 Analysis of Synchronizing Biochemical Networks via Incremental Dissipativity -- 6 Robustness Model Validation of Bistability in Biomolecular Systems -- 7 Meta-DNA: A DNA-Based Approach to Synthetic Biology -- 8 Towards Modeling Automation for Synthetic Biology -- 9 An Investigation of Signal Transduction and Irreversible Decision Making through Monostable and Bistable Switches -- 10 From Specification to Parameters: A Linearization Approach -- 11 Simplified Computational Design of Digital Synthetic Gene Circuits -- 12 Synthetic Biochemical Devices for Programmable Dynamic Behavior -- Index.
Record Nr. UNINA-9910298350503321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Targeted Cancer Treatment in Silico [[electronic resource] ] : Small Molecule Inhibitors and Oncolytic Viruses / / by Natalia L. Komarova, Dominik Wodarz
Targeted Cancer Treatment in Silico [[electronic resource] ] : Small Molecule Inhibitors and Oncolytic Viruses / / by Natalia L. Komarova, Dominik Wodarz
Autore Komarova Natalia L
Edizione [1st ed. 2014.]
Pubbl/distr/stampa New York, NY : , : Springer New York : , : Imprint : Birkhäuser, , 2014
Descrizione fisica 1 online resource (XV, 227 p. 71 illus., 26 illus. in color.) : online resource
Disciplina 616.99406
Collana Modeling and Simulation in Science, Engineering and Technology
Soggetto topico Biomathematics
Cancer research
Oncology  
Applied mathematics
Engineering mathematics
Physiological, Cellular and Medical Topics
Cancer Research
Mathematical and Computational Biology
Oncology
Genetics and Population Dynamics
Applications of Mathematics
ISBN 1-4614-8301-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Background and Scope of the Book -- Part I Treatment of Cancer with Small Molecule Inhibitors -- An Introduction to Small Molecule Inhibitors and Chronic Myeloid Leukemia -- Basic Dynamics of Chronic Myeloid Leukemia During Imatinib Treatment -- Stochastic Modeling of Cellular Growth, Treatment, and Resistance Generation -- Evolutionary Dynamics of Drug Resistant Mutants in Targeted Treatment of CML -- Effect of Cellular Quiescence on the Evolution of Drug Resistance in CML -- Combination Therapies: Short term versus Long term Strategies -- Cross Resistance: Treatment and Modeling -- Mathematical Modeling of Cyclic Cancer Treatments -- Part II Treatment of Cancer with Oncolytic Viruses -- Introduction to Oncolytic Viruses -- Basic Dynamics of Oncolytic Viruses -- Mitotic Virus Transmission and Immune Responses -- Axiomatic Approaches to Oncolytic Virus Modeling -- Spatial Oncolytic Virus Dynamics -- Oncolytic Viruses and the Eradication of Drug-resistant Tumor Cells.
Record Nr. UNINA-9910299975303321
Komarova Natalia L  
New York, NY : , : Springer New York : , : Imprint : Birkhäuser, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Temporal network epidemiology / / Naoki Masuda, Petter Holme, editors
Temporal network epidemiology / / Naoki Masuda, Petter Holme, editors
Pubbl/distr/stampa Singapore : , : Springer, , [2017]
Descrizione fisica 1 online resource (vi, 342 pages) : 121 illustrations, 83 illustrations in color
Disciplina 570.285
Collana Theoretical biology
Soggetto topico Biomathematics
Bioinformatics 
Computational biology 
Epidemiology
Medical microbiology
Systems biology
Biological systems
ISBN 981-10-5287-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910254288403321
Singapore : , : Springer, , [2017]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Theoretical Molecular Biophysics [[electronic resource] /] / by Philipp O.J. Scherer, Sighart F. Fischer
Theoretical Molecular Biophysics [[electronic resource] /] / by Philipp O.J. Scherer, Sighart F. Fischer
Autore Scherer Philipp O.J
Edizione [2nd ed. 2017.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XVI, 513 p. 226 illus., 27 illus. in color.)
Disciplina 572.8
Collana Biological and Medical Physics, Biomedical Engineering
Soggetto topico Biophysics
Biological physics
Biomathematics
Biomedical engineering
Proteins 
Biochemical engineering
Biological and Medical Physics, Biophysics
Mathematical and Computational Biology
Biomedical Engineering and Bioengineering
Protein Science
Biochemical Engineering
ISBN 3-662-55671-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Statistical Mechanics of Biopolymers -- Protein Electrostatics and Solvation -- Reaction Kinetics -- Transport Processes -- Reaction Rate Theory -- Elementary Photophysics -- Elementary Photoinduced Processes -- Molecular Motor Models.
Record Nr. UNINA-9910254586403321
Scherer Philipp O.J  
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Theory and Applications of Difference Equations and Discrete Dynamical Systems [[electronic resource] ] : ICDEA, Muscat, Oman, May 26 - 30, 2013 / / edited by Ziyad AlSharawi, Jim M. Cushing, Saber Elaydi
Theory and Applications of Difference Equations and Discrete Dynamical Systems [[electronic resource] ] : ICDEA, Muscat, Oman, May 26 - 30, 2013 / / edited by Ziyad AlSharawi, Jim M. Cushing, Saber Elaydi
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (229 p.)
Disciplina 512.94
Collana Springer Proceedings in Mathematics & Statistics
Soggetto topico Difference equations
Functional equations
Dynamics
Ergodic theory
Biomathematics
Applied mathematics
Engineering mathematics
Mathematical models
Difference and Functional Equations
Dynamical Systems and Ergodic Theory
Genetics and Population Dynamics
Applications of Mathematics
Mathematical Modeling and Industrial Mathematics
ISBN 3-662-44140-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Papers by Invited Speakers: Competitive exclusion through discrete time models: Azmy S. Ackleh and Paul L. Salceanu -- Benford solutions of linear difference equations: Arno Berger and Gideon Eshun -- Harvesting and dynamics in some one-dimensional population models: Eduardo Liz and Frank M. Hilker -- Chaos and wild chaos in Lorenz-type systems: Hinke M. Osinga, Bernd Krauskopf and Stefanie Hittmeyer -- Contributed Papers: Almost automorphic sequences and their application to a model of cellular neural network: Syed Abbas -- Advances in periodic difference equations with open problems: Ziyad AlSharawi, Jose S. Canovas and Antonio Linero -- An Evolutionary Beverton-Holt Model: J. M. Cushing -- The periodic decomposition problem: Balint Farkas and Szilard Gy. Revesz -- Existence of periodic and almost periodic solutions of discrete Ricker delay models: Yoshihiro Hamaya -- Generalized Lagrange identity for discrete symplectic systems and applications in Weyl-Titchmarsh Theory: Roman Simon Hilscher and Petr Zemanek -- Dynamic selection systems and replicator equations: Zdenek Pospsil -- Asymptotic equivalence of difference equations in Banach Space: Andrejs Reinfelds.
Record Nr. UNINA-9910299968703321
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems [[electronic resource] /] / by Marc Thiriet
Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems [[electronic resource] /] / by Marc Thiriet
Autore Thiriet Marc
Edizione [1st ed. 2013.]
Pubbl/distr/stampa New York, NY : , : Springer New York : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (975 p.)
Disciplina 612.1
Collana Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems
Soggetto topico Biophysics
Biological physics
Biomedical engineering
Biomathematics
Systems biology
Fluid mechanics
Cardiology
Biological and Medical Physics, Biophysics
Biomedical Engineering and Bioengineering
Mathematical and Computational Biology
Systems Biology
Engineering Fluid Dynamics
ISBN 1-299-19734-5
1-4614-5966-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Chapter 1: Blood -- Chapter 2: Hematopoiesis -- Chapter 3: Blood Cells -- Chapter 4: Lymph Drainage -- Chapter 5: Cardiomyocytes -- Chapter 6: Heart Wall -- Chapter 7: Vessel Wall -- Chapter 8: Smooth Myocytes -- Chapter 9: Vascular Endothelium -- Chapter 10: Vascular Growth -- Chapter 11: Tissue Development, Repair, and Remodeling -- Chapter 12: Airway Surface Liquid and Respiratory Mucus -- Chapter 13: Surfactant -- Chapter 14: Conclusion -- References -- List of Currently Used Prefixes and Suffixes -- List of Aliases -- Complementary Lists of Notations -- Index.
Record Nr. UNINA-9910437983103321
Thiriet Marc  
New York, NY : , : Springer New York : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Topics in Mathematical Biology [[electronic resource] /] / by Karl Peter Hadeler
Topics in Mathematical Biology [[electronic resource] /] / by Karl Peter Hadeler
Autore Hadeler Karl Peter
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XIV, 353 p. 28 illus., 2 illus. in color.)
Disciplina 570.151
Collana Lecture Notes on Mathematical Modelling in the Life Sciences
Soggetto topico Biomathematics
Mathematical and Computational Biology
ISBN 3-319-65621-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- 1.Coupling and quiescence -- 2.Delay and age -- 3.Lotka-Volterra and replicator systems -- 4.Ecology -- 5.Homogeneous systems -- 6.Epidemic models -- 7.Coupled movements -- 8.Traveling fronts -- Index.
Record Nr. UNINA-9910254297503321
Hadeler Karl Peter  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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