Autore	Stephanos Joseph J.
Pubbl/distr/stampa	Hoboken, New Jersey : , : Wiley, , 2014
Descrizione fisica	1 online resource (451 p.)
Disciplina	572/.6076
Collana	Wiley Series in Protein and Peptide Science
Soggetto topico	Metalloproteins
ISBN	1-118-80152-0 1-118-80223-3 1-118-80149-0
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Chemistry of Metalloproteins: Problems and Solutions in Bioinorganic Chemistry; Contents; Preface; 1 Introduction; Proteins: Formation, Structures, and Metalloproteins; Organelles and Their Functions; Structure of DNA; Cell Growth and Division; Protein Synthesis; Common Natural α-Amino Acids; Peptide Chain Formation; Protein physiological functions; Structural Features of Proteins; Causes of Polypeptide Chain Folding; Metal Amino Acid Complexes; Comparison of P-O versus M-O Bond Scission Rates for Row 3 Elements; Redox Advantages: Sulfur versus Phosphorus; Bioenergetic Phosphate Derivatives References2 Alkali and Alkaline Earth Cations; References; 3 Nonredox Metalloenzymes; Carboxypeptidases; What are the main functions of carboxypeptidases?; What are the main types of carboxypeptidases?; What are the requirements to stimulate carboxypeptidase-A and carboxypeptidase-B?; What are the main structural features of carboxypeptidase-A and carboxypeptidase-B?; How can Zn2+ be extracted from carboxypeptidase-A and carboxypeptidase-B?What are the consequences of metal ion removal?; What are the spectral consequences when Zn2+ is replaced by Co2+ in carboxypeptidases? Describe the role of Zn2+ in carboxypeptidase-A and carboxypeptidase-B.Design models to mimic the role of the metal ion in carboxypeptidase-A and carboxypeptidase-B.; Carbonic Anhydrase; What are the main functions of carbonic anhydrase?; Conversion of carbonic acid to CO2 and H2O is a spontaneous process. Why is carbonic anhydrase needed?; What are the main structural and chemical features of carbonic anhydrase?; Describe the role of the metal ion in carbonic anhydrase.; What are the possible mechanisms that describe the action of carbonic anhydrase? Design models for the carbonic anhydrase, and what do they reveal?Rate Constants; Alcohol Dehydrogenase; What is the catalytic role and the structural features of the alcohol dehydrogenases?; What is the sequence of events during the reaction of alcohol dehydrogenase?; A number of model systems have been investigated to study the influence of Zn2+ on the reactivity of the carbonyl; give an example.; References; 4 Copper Proteins; Introduction; Electronic Spectra of Copper Ions; What are the structural and spectral features of copper(II)-peptide complexes in the visible region? ESR Spectra of Copper IonsHow can ESR spectra be used as a ``spectral probe ́ ́ to study copper enzymes?; Define; How do the nuclear-spin of Cu2+ ion and the attached ligands affect the ESR signal? How can the hyperfine and superhyperfine splitting be used as a ``spectral probe ́ ́ for studying the copper enzymes?; How may the spectrochemical series and the stereochemistry affect g-values of Cu2+ ion and what is the significance of All-gll trend?; Copper Proteins Identify the significant roles of copper in the biological process, classify, give examples, and explain their functions and main chemical properties.
Record Nr.	UNINA-9910132185603321

Pubbl/distr/stampa	Hoboken, New Jersey : , : Wiley, , [2015]
Descrizione fisica	1 online resource (434 p.)
Disciplina	616.07 616.07540154
Soggetto topico	Imaging systems Imaging systems in medicine Molecular probes
ISBN	1-118-85481-0 1-118-85475-6 1-118-85477-2
Classificazione	TEC015000
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	The Chemistry of Molecular Imaging; Copyright; Contents; Preface; List of Contributors; Chapter 1 An Introduction to Molecular Imaging; 1.1 Introduction; 1.2 What is Positron Emission Tomography (PET)?; 1.2.1 Basic Principles; 1.2.2 Advantages and Limitations; 1.3 What is Single Photon Emission Computed Tomography (SPECT)?; 1.3.1 Basic Principles; 1.3.2 Advantages and Limitations; 1.4 What is Computed Tomography (CT) or Computed Axial Tomography (CAT)?; 1.4.1 Basic Principles; 1.4.2 Advantages and Limitations; 1.5 What is Magnetic Resonance Imaging (MRI)?; 1.5.1 Basic Principles 1.5.2 Advantages and Limitations1.6 What is Optical Imaging?; 1.6.1 Basic Principles; 1.6.2 Conventional or Wide-Field Fluorescence Microscopy; 1.6.3 Confocal Microscopy or Confocal Laser Scanning Microscopy; 1.6.4 Advantages and Limitations; 1.7 What is Ultrasound (US)?; 1.7.1 Basic Principles; 1.7.2 Advantages and Limitations; 1.8 Conclusions; References; Chapter 2 Chemical Methodology for Labelling and Bioconjugation; 2.1 Introduction; 2.2 Chemical Methods; 2.2.1 Through Reactions with Aldehydes or Ketones; 2.2.2 Through Reactions with Azides; 2.2.3 Through Reactions with Alkenes 2.2.4 Cross-Coupling Reactions2.3 Site-Specific Modification of Proteins or Peptides; 2.3.1 N-terminal Cysteine; 2.3.2 Aromatic Residues; 2.3.3 N-terminus of Protein; 2.3.4 C-terminus of Protein; 2.3.5 Introduction of Chemical Tags for Site-Specific Labelling on Peptides or Proteins; 2.4 Conclusions; References; Chapter 3 Recent Developments in the Chemistry of [18F]Fluoride for PET; 3.1 Introduction; 3.2 Fluorine-18: The Starting Material; 3.3 Reactive [18F]Fluoride; 3.4 The Radiofluorination; 3.4.1 Electrophilic Reactions; 3.4.2 Nucleophilic Reactions 3.5 Labelling of Large Biological Molecules3.5.1 The Prosthetic Group Concept; 3.5.2 Prosthetic Entities with Fluorine-18 Bound to Aluminium, Boron, or Silicon; 3.5.3 Click Chemistry; 3.6 Conclusions; References; Chapter 4 Carbon-11, Nitrogen-13, and Oxygen-15 Chemistry: An Introduction to Chemistry with Short-Lived Radioisotopes; 4.1 Introduction; 4.2 Carbon-11 Chemistry; 4.2.1 Synthesis with [11C]Carbon Dioxide; 4.2.2 [11C]methylation Reactions; 4.2.3 [11C]Phosgene Reactions; 4.2.4 [11C]Cyanation Reactions; 4.2.5 [11C]Carbonylation Reactions; 4.3 Nitrogen-13 Chemistry 4.3.1 Synthesis of 13N-labelled Amines4.3.2 Enzymatic Synthesis of 13N-labelled Amino Acid; 4.3.3 Synthesis of [13N]cisplatin; 4.3.4 Synthesis of [13N] Carbamates and Ureas; 4.3.5 Other 13N-labelling Reactions; 4.4 Oxygen-15 Chemistry; 4.5 Conclusions; References; Chapter 5 The Chemistry of Inorganic Nuclides (86Y, 68Ga, 64Cu, 89Zr, 124I); 5.1 Introduction: Inorganic Nuclide-Based Radiopharmaceuticals; 5.2 Radiopharmaceutical Design; 5.3 Radiopharmaceutical Stability; 5.4 86Yttrium Radiometal Ion Properties; 5.4.1 Clinical Trials Based on 86Yttrium; 5.4.2 Recent 86Yttrium Work 5.4.3 Stability of 86Yttrium-Based Radiopharmaceuticals
Record Nr.	UNINA-9910140484103321

Autore	Akasaka Takeshi
Pubbl/distr/stampa	Chichester, West Sussex, : Wiley, 2010
Descrizione fisica	1 online resource (538 p.)
Disciplina	620/.5
Altri autori (Persone)	WudlFred NagaseShigeru
Soggetto topico	Nanotubes Fullerenes Nanodiamonds
ISBN	0-470-97577-6 1-283-13875-1 9786613138750 0-470-66018-X 0-470-66019-8
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Chemistry of Nanocarbons; Contents; Preface; Acknowledgements; Contributors; Abbreviations; 1 Noncovalent Functionalization of Carbon Nanotubes; 2 Supramolecular Assembly of Fullerenes and Carbon Nanotubes Hybrids; 3 Properties of Fullerene-Containing Dendrimers; 4 Novel Electron Donor Acceptor Nanocomposites; 5 Higher Fullerenes: Chirality and Covalent Adducts; 6 Application of Fullerenes to Nanodevices; 7 Supramolecular Chemistry of Fullerenes: Host Molecules for Fullerenes on the Basis of p-p Interaction; 8 Molecular Surgery toward Organic Synthesis of Endohedral Fullerenes 9 New Endohedral Metallofullerenes: Trimetallic Nitride Endohedral Fullerenes10 Recent Progress in Chemistry of Endohedral Metallofullerenes; 11 Gadonanostructures as Magnetic Resonance Imaging Contrast Agents; 12 Chemistry of Soluble Carbon Nanotubes: Fundamentals and Applications; 13 Functionalization of Carbon Nanotubes for Nanoelectronic and Photovoltaic Applications; 14 Dispersion and Separation of Single-walled Carbon Nanotubes; 15 Molecular Encapsulations into Interior Spaces of Carbon Nanotubes and Nanohorns; 16 Carbon Nanotube for Imaging of Single Molecules in Motion 17 Chemistry of Single-Nano Diamond Particles18 Properties of p-electrons in Graphene Nanoribbons and Nanographenes; 19 Carbon Nano Onions; Index; Colour Plates
Record Nr.	UNINA-9910140593403321

Pubbl/distr/stampa	[Place of publication not identified], : Wiley, 1994
Descrizione fisica	1 online resource (963 pages)
Disciplina	547/.0571
Collana	The Chemistry of functional groups The chemistry of organic arsenic, antimony, and bismuth compounds
Soggetto topico	Organoarsenic compounds Organoantimony compounds Organobismuth compounds Organic Chemistry Chemistry Physical Sciences & Mathematics
Soggetto genere / forma	Electronic books.
ISBN	0-470-77911-X 1-280-55435-5 9786610554355 0-470-77258-1 0-470-02347-3
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910146065803321

Autore	Patai Saul
Pubbl/distr/stampa	Chichester [England] ; ; New York, : Wiley, 1989
Descrizione fisica	1 online resource (2 v. (xvi, 1668 p.) ) : ill. ;
Disciplina	547/.08
Altri autori (Persone)	RappoportZvi PataiSaul ApeloigYitzhak
Collana	The Chemistry of functional groups The chemistry of organic silicon compounds The Chemistry of functional groups
Soggetto topico	Organosilicon compounds Composés organosiliciés
Soggetto genere / forma	Electronic books
Soggetto non controllato	Organic silicon compounds
ISBN	1-280-55441-X 9786610554416 0-470-02510-7
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	v. 1. 1989. [pt. 1.] Historical overview and comparison of silicon with carbon / Joyce Y. Corey -- Theoretical aspects of organosilicon compounds / Yitzhak Apeloig -- Structural chemistry of organic silicon compounds / W.S. Sheldrick -- Dynamic stereochemistry at silicon / Robert J.P. Corriu, Christian Guerin and Joel J.E. Moreau -- Thermochemistry / R. Walsh -- Analysis of organosilicon compounds / T.R. Crompton -- Positive and negative ion chemistry of silicon-containing molecules in the gas phase / Helmut Schwarz -- NMR spectroscopy of organosilicon compounds / Elizabeth A. Williams -- Photoelectron Spectra of Silicon Compounds / H. Bock and B. Solouki -- General synthetic pathways to organosilicon compounds / Leonhard Birkofer and Oskar Stuhl -- Recent synthetic applications of organosilanes / Gerald L. Larson -- Acidity, basicity and complex formation of organosilicon compounds / Alan R. Bassindale and Peter G. Taylor -- Reaction mechanisms of nucleophilic attack at silicon / Alan R. Bassindale and Peter G. Taylor -- [pt. 2.] Activating and directive effects of silicon / Alan R. Bassindale and Peter G. Taylor -- The photochemistry of organosilicon compounds / A.G. Brook -- Trivalent silyl ions / Joseph B. Lambert and W.J. Schulz -- Multiple bonds to silicon / Gerhard Raabe and Josef Michl -- Bioorganosilicon chemistry / Reinhold Tacke and Haryanto Linoh -- Polysilanes / Robert West -- Hypervalent silicon compounds / Robert J.P. Corriu and J. Colin Young -- Siloxane polymers and copolymers / T.C. Kendrick, B. Parbhoo and J.W. White -- Organosilicon derivatives of phosphorus, arsenic, antimony and bismuth / D.A. ("Fred") Armitage -- Chemistry of compounds with silicon-sulphur, silicon-selenium and silicon-tellurium bonds / D.A. ("Fred") Armitage -- Transition-metal silyl derivatives / T. Don Tilley -- The hydrosilylation reaction / Iwao Ojima. v. 2. 1998. [pt. 1.] Theoretical aspects and quantum mechanical calculations of silaaromatic compounds / Yitzhak Apeloig and Miriam Karni -- A molecular modeling of the bonded interactions of crystalline silica / G.V. Gibbs and M.B. Boisen -- Polyhedral silicon compounds / Akira Sekiguchi and Shigeru Nagase -- Thermochemistry / Rosa Becerra and Robin Walsh -- The structural chemistry of organosilicon compounds / Menahem Kaftory, Moshe Kapon and Mark Botoshansky -- ²⁹Si NMR spectroscopy of organosilicon compounds / Yoshito Takeuchi and Toshio Takayama -- Activating and directive effects of silicon / Alan R. Bassindale, Simon J. Glynn and Peter G. Taylor -- Steric effects of silyl groups / Jih Ru Hwu, Shwu-Chen Tsay and Buh-Luen Cheng -- Reaction mechanisms of nucleophilic attack at silicon / Alan R. Bassindale, Simon J. Glynn and Peter G. Taylor -- Silicenium ions : quantum chemical computations / Christoph Maerker and Paul von Ragué Schleyer -- Silicenium ions : experimental aspects / Paul D. Lickiss -- Silyl-substituted carbocations / Hans-Ullrich Siehl and Thomas Müller -- Silicon-substituted carbenes / Gerhard Maas -- Alkaline and alkaline earth silyl compounds preparation and structure / Johannes Belzner and Uwe Dehnert -- Mechanism and structures in alcohol addition reactions of disilenes and silenes / Hideki Sakurai -- [pt. 2.] Silicon-carbon and silicon-nitrogen multiply bonded compounds / Thomas Müller, Wolfgang Ziche and Norbert Auner -- Recent advances in the chemistry of silicon-heteroatom multiple bonds / Norihiro Tokitoh and Renji Okazaki -- Gas-phase ion chemistry of silicon-containing molecules / Norman Goldberg and Helmut Schwarz -- Matrix isolation studies of silicon compounds -- Günther Maier [and others] -- Electrochemistry of organosilicon compounds / Toshio Fuchigami -- The photochemistry of organosilicon compounds / A.G. Brook -- Mechanistic aspects of the photochemistry of organosilicon compounds / Mitsuo Kira and Takashi Miyazawa -- Hypervalent silicon compounds / Daniel Kost and Inna Kalikhman -- Silatranes and their tricyclic analogs / Vadim Pestunovich, Svetlana Kirpichenko and Mikhail Voronkov -- Tris(trimethylsilyl)silane in organic synthesis / C. Chatgilialoglu, C. Ferreri and T. Gimisis -- Recent advances in the direct process / Larry N. Lewis -- Acyl silanes / Philip C. Bulman Page, Michael J. McKenzie, Sukhbinder S. Klair and Stephen Rosenthal -- Recent synthetic applications of organosilicon reagents / Ernest W. Colvin -- Recent advances in the hydrosilylation and related reactions / Iwao Ojima, Zhaoyang Li and Jiawang Zhu -- [pt. 3.] Synthetic applications of allylsilanes and vinylsilanes / Tien-Yau Luh and Shiuh-Tzung Liu -- Chemistry of compounds with silicon-sulphur, silicon-selenium and silicon-tellurium bonds / D.A. ("Fred") Armitage -- Cyclic polychalcogenide compounds with silicon / Nami Choi and Wataru Ando -- Organosilicon derivatives of fullerenes / Wataru Ando and Takahiro Kusukawa -- Group 14 metalloles, ionic species and coordination compounds / Jacques Dubac, Christian Guérin and Philippe Meunier -- Transition-metal silyl complexes / Moris S. Eisen -- Cyclopentadienyl silicon compounds / Peter Jutzi -- Recent advances in the chemistry of cyclopolysilanes / Edwin Hengge and Harald Stüger -- Recent advances in the chemistry of siloxane polymers and copolymers / Robert Drake, Iain MacKinnon and Richard Taylor -- Si-containing ceramic precursors / R.M. Laine and A. Sellinger -- Organo-silica sol-gel materials / David Avnir, Lisa C. Klein, David Levy, Ulrich Schubert and Anna B. Wojcik -- Chirality in bioorganosilicon chemistry / Reinhold Tacke and Stephan A. Wagner -- Highly reactive small-ring monosilacycles and medium-ring oligosilacycles / Wataru Ando and Yoshio -- Silylenes / Peter P. Gaspar and Robert West. v. 3. 2001. Theoretical aspects of compounds containing Si, Ge, Sn and Pb / Miriam Karni, Yitzhak Apeloig, Jürgen Kapp and Paul von R. Schleyer -- (Helium I)-photoelectron spectra of silicon compounds : history and achievements concerning their molecular states / H. Bock and B. Solouki -- ²⁹Si NMR experiments in solutions of organosilicon compounds / Jan Schraml -- Silyl radicals / C. Chatgilialoglu and C.H. Schiesser -- Recent advances in the chemistry of silicon-silicon multiple bonds / Manfred Weidenbruch -- Recent developments in the chemistry of compounds with silicon-nitrogen bonds / Peter Neugebauer, Bettina Jaschke and Uwe Klingebiel -- Organosilicon halides : synthesis and properties / Uwe Herzog -- Synthesis of multiply bonded phosphorus compounds using silylphosphines and silylphosphides / Masaaki Yoshifuji and Kozo Toyota -- Polysilanes : conformations, chromotropism and conductivity / Robert West -- Nanostructured hybrid organic-inorganic solids : from molecules to materials / Bruno Boury and Robert J.P. Corriu -- Polysiloles and related silole-containing polymers / Shigehiro Yamaguchi and Kohei Tamao -- Polysilanols / Paul D. Lickiss -- Silicon-based dendrimers and hyperbranched polymers / David Y. Son -- Biotechnology reveals new routes to synthesis and structural control of silica and polysilsesquioxanes / Daniel E. Morse -- Chemistry on silicon surfaces / Cheol Ho Choi and Mark S. Gordon -- Silyl migrations / Mitsuo Kira and Takeaki Iwamoto -- Kinetic studies of the reactions of Si=C and Si=Si bonds / Tracy L. Morkin, Thomas R. Owens and William J. Leigh -- Ion-molecule reactions of silicon cations / Simonetta Fornarini.
Record Nr.	UNINA-9910146066303321